PL3781558T3 - Inhibitory funkcji płytek krwi i sposoby ich zastosowania - Google Patents

Inhibitory funkcji płytek krwi i sposoby ich zastosowania

Info

Publication number
PL3781558T3
PL3781558T3 PL19722359.7T PL19722359T PL3781558T3 PL 3781558 T3 PL3781558 T3 PL 3781558T3 PL 19722359 T PL19722359 T PL 19722359T PL 3781558 T3 PL3781558 T3 PL 3781558T3
Authority
PL
Poland
Prior art keywords
inhibitors
methods
same
platelet function
platelet
Prior art date
Application number
PL19722359.7T
Other languages
English (en)
Inventor
Michael Holinstat
Reheman Adili
Andrew White
Theodore R. Holman
Original Assignee
The Regents Of The University Of Michigan
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of Michigan, The Regents Of The University Of California filed Critical The Regents Of The University Of Michigan
Publication of PL3781558T3 publication Critical patent/PL3781558T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL19722359.7T 2018-04-17 2019-04-17 Inhibitory funkcji płytek krwi i sposoby ich zastosowania PL3781558T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862659024P 2018-04-17 2018-04-17
PCT/US2019/027881 WO2019204447A1 (en) 2018-04-17 2019-04-17 Inhibitors of platelet function and methods for use of the same

Publications (1)

Publication Number Publication Date
PL3781558T3 true PL3781558T3 (pl) 2023-05-02

Family

ID=66429584

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19722359.7T PL3781558T3 (pl) 2018-04-17 2019-04-17 Inhibitory funkcji płytek krwi i sposoby ich zastosowania

Country Status (9)

Country Link
US (3) US11498905B2 (pl)
EP (1) EP3781558B1 (pl)
CN (1) CN113015725B (pl)
CA (1) CA3134447A1 (pl)
DK (1) DK3781558T3 (pl)
ES (1) ES2942214T3 (pl)
HU (1) HUE062236T2 (pl)
PL (1) PL3781558T3 (pl)
WO (1) WO2019204447A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026085283A1 (en) 2024-10-16 2026-04-23 Regents Of The University Of Michigan Cs585 (5-((4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butyl)thio)-2,4-dihydro-3h-1,2,4-triazol-3-one) for use in treating inflammatory and autoimmune disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5504259B2 (ja) 2008-05-19 2014-05-28 メルク・シャープ・アンド・ドーム・コーポレーション 第ixa因子阻害剤としての複素環式化合物
TW201319068A (zh) * 2011-08-05 2013-05-16 必治妥美雅史谷比公司 作為xia因子抑制劑之環狀p1接合劑
CN107849026B (zh) * 2015-07-29 2021-01-01 百时美施贵宝公司 携带烷基或环烷基p2′部分的因子xia大环抑制剂
EP3475442B1 (en) 2016-06-23 2024-10-23 The Regents of The University of Michigan 12(s)-hydroxyeicosatrienoic acid compounds and their use as therapeutic agents

Also Published As

Publication number Publication date
HUE062236T2 (hu) 2023-10-28
US20260035352A1 (en) 2026-02-05
DK3781558T3 (da) 2023-04-03
CA3134447A1 (en) 2019-10-24
US12269805B2 (en) 2025-04-08
ES2942214T3 (es) 2023-05-30
WO2019204447A1 (en) 2019-10-24
CN113015725A (zh) 2021-06-22
CN113015725B (zh) 2024-08-13
EP3781558A1 (en) 2021-02-24
EP3781558B1 (en) 2023-03-01
US20210363113A1 (en) 2021-11-25
US20230140210A1 (en) 2023-05-04
US11498905B2 (en) 2022-11-15

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