PL378291A1 - Wytwarzanie komórek dendrytycznych z monocytarnych prekursorów komórek dendrytycznych z zastosowaniem GM-CSF w nieobecności dodatkowych cytokin - Google Patents
Wytwarzanie komórek dendrytycznych z monocytarnych prekursorów komórek dendrytycznych z zastosowaniem GM-CSF w nieobecności dodatkowych cytokinInfo
- Publication number
- PL378291A1 PL378291A1 PL378291A PL37829104A PL378291A1 PL 378291 A1 PL378291 A1 PL 378291A1 PL 378291 A PL378291 A PL 378291A PL 37829104 A PL37829104 A PL 37829104A PL 378291 A1 PL378291 A1 PL 378291A1
- Authority
- PL
- Poland
- Prior art keywords
- cells
- csf
- dendritic
- monocytes
- dendritic cells
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/70—Undefined extracts
- C12N2500/72—Undefined extracts from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/70—Non-animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/10—Mineral substrates
- C12N2533/12—Glass
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45101503P | 2003-02-27 | 2003-02-27 | |
| PCT/US2004/006119 WO2004076651A2 (en) | 2003-02-27 | 2004-02-27 | Generation of dendritic cells from monocytic dendritic precursor cells with gm-csf in the absence of additional cytokines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL378291A1 true PL378291A1 (pl) | 2006-03-20 |
| PL209998B1 PL209998B1 (pl) | 2011-11-30 |
Family
ID=32927693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL378291A PL209998B1 (pl) | 2003-02-27 | 2004-02-27 | Sposób in vitro lub ex vivo różnicowania monocytarnych prekursorów komórek dendrytycznych w niedojrzale komórki dendrytyczne |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US8389278B2 (pl) |
| EP (1) | EP1604016B1 (pl) |
| JP (1) | JP4762887B2 (pl) |
| KR (2) | KR101201875B1 (pl) |
| CN (1) | CN1784488B (pl) |
| AT (1) | ATE420946T1 (pl) |
| AU (2) | AU2004214896A1 (pl) |
| BR (1) | BRPI0407900A (pl) |
| CA (1) | CA2517295C (pl) |
| CY (1) | CY1109099T1 (pl) |
| DE (1) | DE602004019057D1 (pl) |
| DK (1) | DK1604016T3 (pl) |
| ES (1) | ES2321939T3 (pl) |
| IL (1) | IL170512A (pl) |
| MX (1) | MXPA05009178A (pl) |
| NZ (1) | NZ542071A (pl) |
| PL (1) | PL209998B1 (pl) |
| RU (1) | RU2364625C2 (pl) |
| TW (1) | TW200506061A (pl) |
| WO (1) | WO2004076651A2 (pl) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040057935A1 (en) * | 2002-09-20 | 2004-03-25 | Cedars-Sinai Medical Center | Intratumoral delivery of dendritic cells |
| CN102600461B (zh) * | 2002-12-06 | 2017-07-14 | 西北生物治疗药物公司 | 给予体外部分成熟的树突细胞治疗肿瘤 |
| EP1670513B1 (en) * | 2003-10-06 | 2013-01-23 | Cedars-Sinai Medical Center | Cox-2 inhibitors and dendritic cells for use in the treatment of cancer. |
| JP5015601B2 (ja) * | 2003-10-21 | 2012-08-29 | セダーズ−シナイ メディカル センター | 中枢神経系の癌を含む癌の処置のための系および方法 |
| US7790039B2 (en) * | 2003-11-24 | 2010-09-07 | Northwest Biotherapeutics, Inc. | Tangential flow filtration devices and methods for stem cell enrichment |
| JP5020935B2 (ja) | 2005-04-08 | 2012-09-05 | アルゴス セラピューティクス,インコーポレイティド | 樹状細胞組成物および方法 |
| KR20220113543A (ko) * | 2005-12-08 | 2022-08-12 | 노쓰웨스트 바이오써라퓨틱스, 인크. | 미성숙 단핵구성 수지상 세포의 활성화를 유도하기 위한 조성물 및 방법 |
| EP1806395A1 (en) * | 2006-01-06 | 2007-07-11 | Stichting Sanquin Bloedvoorziening | Maturation of dendritic cells |
| CA2700573C (en) | 2006-09-26 | 2016-11-22 | Cedars-Sinai Medical Center | Cancer stem cell antigen vaccines and methods |
| CA2700436C (en) | 2006-09-28 | 2017-04-18 | John S. Yu | Cancer vaccines and vaccination methods |
| PL1920781T3 (pl) * | 2006-11-10 | 2015-06-30 | Glycotope Gmbh | Kompozycje zawierające core-1-dodatnie mikroorganizmy i ich zastosowanie w leczeniu lub profilaktyce nowotworów |
| KR100896747B1 (ko) | 2007-05-30 | 2009-05-11 | 동아대학교 산학협력단 | 후코이단 또는 그 유사체를 함유하는 수지상 세포의 성숙화유도용 조성물 |
| US8728465B2 (en) * | 2008-06-17 | 2014-05-20 | Cedars-Sinai Medical Center | Use of toll-like receptor ligands as adjuvants to vaccination therapy for brain tumors |
| PL2328923T3 (pl) | 2008-09-02 | 2016-06-30 | Cedars Sinai Medical Center | Epitopy CD133 |
| JP2010063404A (ja) * | 2008-09-10 | 2010-03-25 | Olympus Corp | 幹細胞の分離方法 |
| FR2940451B1 (fr) * | 2008-12-18 | 2014-09-12 | Proteus | Procede d'evaluation de l'immunogenicite des proteines |
| EP2427485B1 (en) * | 2009-05-07 | 2016-12-07 | ImmunoCellular Therapeutics, Ltd. | Cd133 epitopes |
| WO2011011688A2 (en) * | 2009-07-24 | 2011-01-27 | Rhode Island Hospital | DENDRITIC CELL VACCINES FOR ASPARAGINYL- β - HYDROXYLASE EXPRESSING TUMORS |
| CA2777400C (en) | 2009-10-12 | 2018-11-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Granulysin in immunotherapy |
| RU2575978C2 (ru) * | 2010-03-15 | 2016-02-27 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Система и способ получения и хранения активированных зрелых дендритных клеток |
| RU2458985C1 (ru) * | 2011-03-18 | 2012-08-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт клинической иммунологии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИКИ" СО РАМН) | Способ генерации антиген-специфических цитотоксических клеток с противоопухолевой активностью |
| DE13746292T1 (de) * | 2012-02-10 | 2014-10-30 | Hakushinkouseikai Foundation | Proliferationsmittel für monozyten, kulturmedium zur proliferation von monozyten, verfahren zur herstellung von monozyten, verfahren zur herstellung dendritischer zellen und verfahren zur herstellung eines impfstoffs mit dendritischen zellen |
| ES2662333T3 (es) | 2013-02-14 | 2018-04-06 | Immunocellular Therapeutics Ltd. | Vacunas contra el cáncer y métodos de vacunación |
| WO2016011878A1 (zh) * | 2014-07-23 | 2016-01-28 | 国家纳米科学中心 | 一种抑制肿瘤转移和治疗白血病的多肽和多肽复合物、其制备方法及其应用 |
| CN104098652B (zh) * | 2014-07-23 | 2016-11-09 | 国家纳米科学中心 | 一种抑制肿瘤转移的多肽和多肽复合物、其制备方法及其应用 |
| IL256522B2 (en) * | 2015-06-30 | 2024-10-01 | Northwest Biotherapeutics Inc | Optimally activated dendritic cells that result in an enhanced or enhanced antitumor immune response |
| RU2749610C2 (ru) * | 2015-09-15 | 2021-06-16 | Нортвест Байотерапьютикс, Инк. | Способы, относящиеся к композициям активированных дендритных клеток и к иммунотерапевтическому лечению индивидуумов с прогрессирующим раком |
| CN105483084A (zh) * | 2016-01-04 | 2016-04-13 | 英普乐孚生物技术(上海)有限公司 | 肿瘤抗原靶向性dc细胞的制备方法 |
| EP3810641A4 (en) | 2018-06-19 | 2022-07-13 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | ONCOLYTIC VIRUS OR ANTIGEN PRESENT CELL MEDIATED CANCER THERAPY USING TYPE I INTERFERON AND CD40 LIGAND |
| KR102159766B1 (ko) * | 2018-11-12 | 2020-09-24 | 조선대학교산학협력단 | 홍조류추출물을 이용한 미성숙수지상세포 분화유도용 배지조성물 및 미성숙수지상세포 분화유도방법 |
| EP3945815A4 (en) * | 2019-04-03 | 2023-04-19 | Akron Biotechnology, LLC | CRYOPRESERVATION AND CELL CULTURE MEDIA |
| US20220273709A1 (en) * | 2019-07-12 | 2022-09-01 | Kyushu University, National University Corporation | Development of therapy for improving myocardial contraction and method for inhibiting cardiomyocyte death |
| EP4061423A4 (en) * | 2019-11-18 | 2023-12-06 | Children's Medical Center Corporation | HYPERACTIVE DENDRITIC CELLS FOR PERMANENT ANTITUMOR EFFECT ON ADOPTIONAL CELL TRANSFER BASIS |
| KR102904431B1 (ko) * | 2021-05-07 | 2025-12-26 | (주)나노팬텍 | 수지상 세포의 배양 방법 |
| US20240207308A1 (en) * | 2021-05-07 | 2024-06-27 | NANOFAENTECH CO., Ltd. | Method for culturing dendritic cells |
| CN113881632B (zh) * | 2021-09-29 | 2023-09-29 | 四川省医学科学院·四川省人民医院 | 一种提高dc细胞活性的细胞培养基及培养方法 |
| US12584107B2 (en) * | 2022-01-20 | 2026-03-24 | 3T Biosciences, Inc. | T cell receptor (TCR) compositions and methods for optimizing antigen reactive T-cells |
| US20230287080A1 (en) * | 2022-01-20 | 2023-09-14 | 3T Biosciences, Inc. | T cell receptor (tcr) compositions and methods for optimizing antigen reactive t-cells |
| GB2624871A (en) * | 2022-11-29 | 2024-06-05 | Alv B As | Process for preparing a population of dendritic cells and immunotherapy using the same |
| CN118389430A (zh) * | 2024-04-12 | 2024-07-26 | 广东壹加再生医学研究院有限公司 | 一种高抗肿瘤特异性dc-cik细胞的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3683956D1 (de) * | 1985-06-11 | 1992-04-02 | Us Commerce | In einem serumfreien medium in suspension kultivierte humane monozyten. |
| US5162504A (en) * | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
| DE69333433T2 (de) | 1992-04-01 | 2004-12-02 | The Rockefeller University | Verfahren zur in vitro kultivierung dendritischer vorläuferzellen und deren verwendung zur immunogen herstellung |
| US6010905A (en) * | 1995-01-27 | 2000-01-04 | The United States Of America As Represented By The Department Of Health & Human Services | Method for inducing monocytes to exhibit the phenotype of activated myeloid dendritic cells |
| US5788963A (en) * | 1995-07-31 | 1998-08-04 | Pacific Northwest Cancer Foundation | Isolation and/or preservation of dendritic cells for prostate cancer immunotherapy |
| US7659119B2 (en) * | 1996-02-12 | 2010-02-09 | Argos Therapeutics, Inc. | Method and compositions for obtaining mature dendritic cells |
| US20020094545A1 (en) | 2000-11-30 | 2002-07-18 | Harris Paul E. | Growth of human dendritic cells for cancer immunotherapy in closed system using microcarrier beads |
| AU2002326463A1 (en) * | 2001-07-25 | 2003-02-17 | Northwest Biotherapeutics, Inc. | Methods and apparatus for enrichment and culture of monocytic dendritic cell precursors |
| CA2459713C (en) * | 2001-09-06 | 2015-08-18 | Northwest Biotherapeutics, Inc. | Compositions and methods for priming monocytic dendritic cells and t cells for th-1 response |
| CN1713951B (zh) * | 2002-06-19 | 2010-05-26 | 西北生物治疗药物公司 | 切向流过滤设备和白细胞富集方法 |
| MXPA05008486A (es) * | 2003-02-10 | 2005-11-17 | Northwest Biotherapeutics Inc | Celulas presentadoras de antigeno cd14+ cultivadas. |
-
2004
- 2004-02-27 RU RU2005129561/13A patent/RU2364625C2/ru active
- 2004-02-27 JP JP2006503922A patent/JP4762887B2/ja not_active Expired - Fee Related
- 2004-02-27 PL PL378291A patent/PL209998B1/pl unknown
- 2004-02-27 KR KR1020057016059A patent/KR101201875B1/ko not_active Expired - Fee Related
- 2004-02-27 TW TW093105079A patent/TW200506061A/zh unknown
- 2004-02-27 ES ES04715780T patent/ES2321939T3/es not_active Expired - Lifetime
- 2004-02-27 NZ NZ542071A patent/NZ542071A/en not_active IP Right Cessation
- 2004-02-27 BR BRPI0407900-0A patent/BRPI0407900A/pt not_active Application Discontinuation
- 2004-02-27 MX MXPA05009178A patent/MXPA05009178A/es active IP Right Grant
- 2004-02-27 US US10/789,807 patent/US8389278B2/en not_active Expired - Fee Related
- 2004-02-27 DK DK04715780T patent/DK1604016T3/da active
- 2004-02-27 CA CA2517295A patent/CA2517295C/en not_active Expired - Lifetime
- 2004-02-27 EP EP04715780A patent/EP1604016B1/en not_active Expired - Lifetime
- 2004-02-27 CN CN2004800105421A patent/CN1784488B/zh not_active Expired - Fee Related
- 2004-02-27 AT AT04715780T patent/ATE420946T1/de not_active IP Right Cessation
- 2004-02-27 DE DE602004019057T patent/DE602004019057D1/de not_active Expired - Lifetime
- 2004-02-27 WO PCT/US2004/006119 patent/WO2004076651A2/en not_active Ceased
- 2004-02-27 KR KR1020117021421A patent/KR20110106474A/ko not_active Ceased
- 2004-02-27 AU AU2004214896A patent/AU2004214896A1/en not_active Abandoned
-
2005
- 2005-08-25 IL IL170512A patent/IL170512A/en active IP Right Grant
-
2009
- 2009-04-14 CY CY20091100437T patent/CY1109099T1/el unknown
-
2010
- 2010-04-01 AU AU2010201319A patent/AU2010201319B2/en not_active Ceased
-
2013
- 2013-03-05 US US13/786,208 patent/US9102917B2/en not_active Expired - Lifetime
-
2015
- 2015-07-30 US US14/814,315 patent/US10731130B2/en not_active Expired - Fee Related
-
2020
- 2020-08-03 US US16/983,300 patent/US11827903B2/en not_active Expired - Lifetime
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