PL378326A1 - Pochodne pirydyny użyteczne do inhibitowania układu wymiany sód/wapń - Google Patents

Pochodne pirydyny użyteczne do inhibitowania układu wymiany sód/wapń

Info

Publication number
PL378326A1
PL378326A1 PL378326A PL37832604A PL378326A1 PL 378326 A1 PL378326 A1 PL 378326A1 PL 378326 A PL378326 A PL 378326A PL 37832604 A PL37832604 A PL 37832604A PL 378326 A1 PL378326 A1 PL 378326A1
Authority
PL
Poland
Prior art keywords
exchange system
pyridine derivatives
derivatives useful
calcium exchange
inhibiting sodium
Prior art date
Application number
PL378326A
Other languages
English (en)
Inventor
Leena Otsomaa
Tuula Koskelainen
Arto Karjalainen
Sirpa Rasku
Piero Pollesello
Jouko Levijoki
Original Assignee
Orion Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8565286&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL378326(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orion Corporation filed Critical Orion Corporation
Publication of PL378326A1 publication Critical patent/PL378326A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL378326A 2003-01-09 2004-01-09 Pochodne pirydyny użyteczne do inhibitowania układu wymiany sód/wapń PL378326A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20030030A FI20030030A0 (fi) 2003-01-09 2003-01-09 Uusia yhdisteitä

Publications (1)

Publication Number Publication Date
PL378326A1 true PL378326A1 (pl) 2006-03-20

Family

ID=8565286

Family Applications (1)

Application Number Title Priority Date Filing Date
PL378326A PL378326A1 (pl) 2003-01-09 2004-01-09 Pochodne pirydyny użyteczne do inhibitowania układu wymiany sód/wapń

Country Status (22)

Country Link
US (1) US7482340B2 (pl)
EP (1) EP1583759A1 (pl)
JP (1) JP2006516271A (pl)
KR (1) KR20050095601A (pl)
CN (1) CN100457752C (pl)
AR (1) AR042733A1 (pl)
AU (1) AU2004203943B2 (pl)
BR (1) BRPI0406669A (pl)
CA (1) CA2512184A1 (pl)
EA (1) EA008539B1 (pl)
FI (1) FI20030030A0 (pl)
HR (1) HRP20050703A2 (pl)
IL (1) IL169435A0 (pl)
IS (1) IS7969A (pl)
MX (1) MXPA05007435A (pl)
NO (1) NO20053730L (pl)
NZ (1) NZ541087A (pl)
PL (1) PL378326A1 (pl)
RS (1) RS20050528A (pl)
UA (1) UA81941C2 (pl)
WO (1) WO2004063191A1 (pl)
ZA (1) ZA200505461B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20011507A0 (fi) * 2001-07-10 2001-07-10 Orion Corp Uusia yhdisteitä
KR101233223B1 (ko) * 2004-12-21 2013-02-14 제이엔씨 석유 화학 주식회사 크로만환을 가지는 액정 화합물, 액정 조성물 및 이 액정조성물을 함유하는 액정 표시소자
JP2010519267A (ja) * 2007-02-22 2010-06-03 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 新規殺微生物剤
EP2649066B1 (en) * 2010-12-06 2015-10-21 Autifony Therapeutics Limited Hydantoin derivatives useful as kv3 inhibitors
EP2524908A1 (en) * 2011-05-20 2012-11-21 LEK Pharmaceuticals d.d. Process for the preparation of alfa-substituted ketones and their application in synthesis of pharmaceutically active compounds
US8912224B2 (en) 2011-09-12 2014-12-16 Sanofi Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals
JP5941637B2 (ja) * 2011-09-12 2016-06-29 サノフイ 置換２−（クロマン−６−イルオキシ）−チアゾール及び医薬としてのその使用
SG11201400518RA (en) 2011-09-12 2014-04-28 Sanofi Sa Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals
RS53748B1 (sr) * 2011-09-12 2015-06-30 Sanofi Supstituisani 2-(hroman-6-iloksi)-tiazoli i njihova upotreba kao farmaceutskih sredstava
WO2013144191A1 (de) * 2012-03-29 2013-10-03 Bayer Intellectual Property Gmbh Substituierte 2 -amino - 3 - cyanopyridine als inhibitoren des natrium calcium austausches und ihre verwendung bei kardiovaskulären erkrankungen
TWI633095B (zh) * 2013-03-08 2018-08-21 賽諾菲公司 經取代－６－基氧基－環烷類及其作為醫藥品之用途
GB201416186D0 (en) 2014-09-12 2014-10-29 Redx Pharma Ltd Compounds
EP3265445B1 (en) 2015-03-06 2021-05-05 Pharmakea, Inc. Lysyl oxidase-like 2 inhibitors and uses thereof
AU2016229268B2 (en) 2015-03-06 2020-09-10 Pharmakea, Inc. Fluorinated lysyl oxidase-like 2 inhibitors and uses thereof
WO2017030169A1 (ja) * 2015-08-19 2017-02-23 日産化学工業株式会社 液晶配向剤などに用いられる新規なイミド系重合体
CA3036064A1 (en) 2016-09-07 2018-03-15 Pharmakea, Inc. Crystalline forms of a lysyl oxidase-like 2 inhibitor and methods of making
WO2018048942A1 (en) 2016-09-07 2018-03-15 Pharmakea, Inc. Uses of a lysyl oxidase-like 2 inhibitor
WO2019175464A1 (en) 2018-03-14 2019-09-19 Orion Corporation Compounds useful as inhibitors of sodium-calcium exchanger (ncx)
EP4188552A2 (en) 2020-07-28 2023-06-07 Jazz Pharmaceuticals Ireland Limited Fused bicyclic raf inhibitors and methods for use thereof
CN115850258B (zh) * 2022-12-27 2024-09-24 东北林业大学 一种马赛替尼的合成方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2820817A (en) * 1954-02-04 1958-01-21 Mcneilab Inc Oxygenated indan compounds and method of making the same
US3862232A (en) * 1963-07-03 1975-01-21 Upjohn Co 1-(p-hydroxyphenyl)-2-phenyl-6-(2-diethylaminoethoxy)-3,4-dihydronaphthalene and the salts thereof
BE650081A (pl) 1963-07-03
GB1154119A (en) 1968-05-20 1969-06-04 Merck Ag E 3-Alkyl-Flavanones
JPH04113839A (ja) * 1990-09-05 1992-04-15 Mitsubishi Petrochem Co Ltd ポリカーボネート樹脂積層物
FR2733685B1 (fr) * 1995-05-05 1997-05-30 Adir Utilisation des derives du benzopyrane pour l'obtention de compositions pharmaceutiques destinees au traitement des pathologies liees a l'echangeur c1-/hc03-, na+ independant
JPH0967336A (ja) 1995-09-04 1997-03-11 Kanebo Ltd 新規なイソチオウレア誘導体
DE69810606T2 (de) 1997-03-27 2003-10-09 Taisho Pharmaceutical Co., Ltd. 2-phenoxyanilinderivate
JPH1149752A (ja) * 1997-08-05 1999-02-23 Taisho Pharmaceut Co Ltd フェノキシピリジン誘導体
DE19742508A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen
DK1031556T3 (da) 1997-10-20 2003-02-24 Taisho Pharmaceutical Co Ltd 2-phenoxyanilinderivater
JPH11302235A (ja) 1998-04-15 1999-11-02 Taisho Pharmaceut Co Ltd フェノキシアルキルアミン誘導体
JP2002542291A (ja) 1999-04-23 2002-12-10 ブリストル−マイヤーズ スクイブ カンパニー ジ環式アシルグアニジン・ナトリウム／プロトン交換抑制剤および方法
CA2383583C (en) * 1999-09-17 2009-04-07 Nissan Chemical Industries, Ltd. Benzopyran derivative
FI20011507A0 (fi) 2001-07-10 2001-07-10 Orion Corp Uusia yhdisteitä

Also Published As

Publication number Publication date
NO20053730L (no) 2005-10-07
KR20050095601A (ko) 2005-09-29
JP2006516271A (ja) 2006-06-29
HRP20050703A2 (en) 2005-10-31
AU2004203943B2 (en) 2009-09-17
FI20030030A0 (fi) 2003-01-09
UA81941C2 (uk) 2008-02-25
MXPA05007435A (es) 2005-09-12
BRPI0406669A (pt) 2005-12-20
CN1745078A (zh) 2006-03-08
ZA200505461B (en) 2006-03-29
NO20053730D0 (no) 2005-08-03
EA008539B1 (ru) 2007-06-29
RS20050528A (sr) 2007-06-04
IS7969A (is) 2005-08-02
US20060241147A1 (en) 2006-10-26
EA200501104A1 (ru) 2005-12-29
WO2004063191A1 (en) 2004-07-29
CN100457752C (zh) 2009-02-04
EP1583759A1 (en) 2005-10-12
AU2004203943A1 (en) 2004-07-29
NZ541087A (en) 2008-04-30
CA2512184A1 (en) 2004-07-29
IL169435A0 (en) 2007-07-04
AR042733A1 (es) 2005-06-29
US7482340B2 (en) 2009-01-27

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