PL3828203T3 - Compositions and methods for treating fatty tissue buildup - Google Patents

Compositions and methods for treating fatty tissue buildup

Info

Publication number
PL3828203T3
PL3828203T3 PL20203790.9T PL20203790T PL3828203T3 PL 3828203 T3 PL3828203 T3 PL 3828203T3 PL 20203790 T PL20203790 T PL 20203790T PL 3828203 T3 PL3828203 T3 PL 3828203T3
Authority
PL
Poland
Prior art keywords
compositions
methods
fatty tissue
treating fatty
tissue buildup
Prior art date
Application number
PL20203790.9T
Other languages
Polish (pl)
Inventor
Michael M. Wolfe
Michael O. Boylan
Original Assignee
Mhs Care - Innovation Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mhs Care - Innovation Llc filed Critical Mhs Care - Innovation Llc
Publication of PL3828203T3 publication Critical patent/PL3828203T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
PL20203790.9T 2013-12-17 2014-12-17 Compositions and methods for treating fatty tissue buildup PL3828203T3 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361917136P 2013-12-17 2013-12-17
US201461974660P 2014-04-03 2014-04-03
US201462007255P 2014-06-03 2014-06-03
US201462045189P 2014-09-03 2014-09-03
US201462074234P 2014-11-03 2014-11-03
US201462074225P 2014-11-03 2014-11-03
US201462074227P 2014-11-03 2014-11-03

Publications (1)

Publication Number Publication Date
PL3828203T3 true PL3828203T3 (en) 2024-10-21

Family

ID=52278851

Family Applications (2)

Application Number Title Priority Date Filing Date
PL20203790.9T PL3828203T3 (en) 2013-12-17 2014-12-17 Compositions and methods for treating fatty tissue buildup
PL14822035T PL3083683T3 (en) 2013-12-17 2014-12-17 Compositions and methods for treating fatty tissue buildup

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL14822035T PL3083683T3 (en) 2013-12-17 2014-12-17 Compositions and methods for treating fatty tissue buildup

Country Status (15)

Country Link
US (3) US9771422B2 (en)
EP (3) EP4410833A3 (en)
JP (3) JP6328769B2 (en)
CN (2) CN113633768B (en)
AU (1) AU2014364768B2 (en)
BR (1) BR112016014042A2 (en)
CA (1) CA2934004C (en)
DK (2) DK3083683T3 (en)
ES (2) ES2984113T3 (en)
HU (1) HUE067414T2 (en)
IL (1) IL246269B (en)
MX (1) MX382215B (en)
PL (2) PL3828203T3 (en)
RU (1) RU2711478C2 (en)
WO (1) WO2015095354A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11066467B2 (en) 2013-12-17 2021-07-20 Mhs Care-Innovation Llc Compositions and methods for treating ischemic heart disease
RU2711478C2 (en) 2013-12-17 2020-01-17 ЭмЭйчЭс КЕА-ИННОВЕЙШН ЭлЭлСи Compositions and methods for controlling accumulation of adipose tissue
US10548951B2 (en) 2013-12-17 2020-02-04 Mhs Care-Innovation Llc Compositions and methods for treating obesity and hyperphagia
UA127495C2 (en) 2015-12-23 2023-09-13 Амджен Інк. Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
WO2018102654A1 (en) * 2016-12-01 2018-06-07 Mhs Care-Innovation Llc Compositions and methods for treating obesity and hyperphagia
IL313587A (en) 2017-01-17 2024-08-01 Amgen Inc Method for treating or ameliorating metabolic disorders using GLP-1 receptor agonists conjugated to gastric inhibitory peptide receptor antagonists
EA201992502A1 (en) * 2017-06-20 2020-04-22 Эмджен Инк. METHOD FOR TREATING OR REDUCING THE INTENSITY OF METABOLIC DISORDERS WITH APPLICATION OF PROTEINS BINDING THE GASTROINhibitor PEPTIDE RECEPTOR (GIPR) IN COMBINATION WITH GL 1 AGONISTS
EP3642238A1 (en) 2017-06-21 2020-04-29 Amgen Inc. Method of treating or ameliorating metabolic disorders using antagonistic binding proteins for gastric inhibitory peptide receptor (gipr)/glp-1 receptor agonist fusion proteins
EP4058482A2 (en) * 2019-11-07 2022-09-21 Amgen Inc. Method of treating or ameliorating cushing's syndrome using binding proteins for gastric inhibitory peptide receptor (gipr)
WO2021196225A1 (en) * 2020-04-03 2021-10-07 Hjb (Hangzhou) Co., Ltd. Molecular antagonist of gastric inhibitory polypeptide, compositions comprising molecular antagoist of gastric inhibitory polypeptide, and method for treatment of diseases using the same
EP4687947A1 (en) 2023-04-05 2026-02-11 Antag Therapeutics ApS Gip activity modulators and orthostatic intolerance
WO2025226312A1 (en) * 2024-04-25 2025-10-30 Incregen Therapeutics Llc Fc-null anti-gip antibodies

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WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US5646253A (en) * 1994-03-08 1997-07-08 Memorial Sloan-Kettering Cancer Center Recombinant human anti-LK26 antibodies
US5229137A (en) 1992-05-06 1993-07-20 Brigham And Women's Hospital, Inc. Methods and pharmaceutical compositions for treating episodic heartburn
US7091183B1 (en) 1996-12-03 2006-08-15 Boston Medical Center Corporation Specific antagonists for glucose-dependent insulinotropic polypeptide (GIP)
WO2003103697A2 (en) 2002-06-11 2003-12-18 Cell Therapeutics Scandinavia Ab Use of compounds having gip activity for the treatment of disorders associated with abnormal loss of cells and/or for the treatment of obesity
US20040146512A1 (en) 2002-10-09 2004-07-29 Arnon Rosenthal Methods of treating Alzheimer's disease using antibodies directed against amyloid beta peptide and compositions thereof
RU2339398C2 (en) * 2002-10-22 2008-11-27 Уэйрейта Фармасьютиклз, Инк. Diabetes treatment
AU2005298689A1 (en) * 2004-10-25 2006-05-04 Cytos Biotechnology Ag Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof
US20060275288A1 (en) 2005-01-20 2006-12-07 Grihalde Nelson D GLP-1 receptor agonist and allosteric modulator monoclonal antibodies and uses thereof
EP2441838A3 (en) * 2006-01-24 2013-07-10 Domantis Limited Fusion proteins that contain natural junctions
US8226949B2 (en) 2006-06-23 2012-07-24 Aegis Therapeutics Llc Stabilizing alkylglycoside compositions and methods thereof
CN101610780A (en) * 2006-09-13 2009-12-23 纽约市哥伦比亚大学托管会 Undercarboxylated/uncarboxylated osteocalcin enhances β-cell proliferation, insulin secretion, insulin sensitivity, glucose tolerance and reduces fat mass
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WO2012092539A2 (en) * 2010-12-31 2012-07-05 Takeda Pharmaceutical Company Limited Antibodies to dll4 and uses thereof
JP2014508165A (en) * 2011-03-02 2014-04-03 モルフォテック、インク. Co-administration of eribulin and farletuzumab for the treatment of breast cancer
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RU2711478C2 (en) 2013-12-17 2020-01-17 ЭмЭйчЭс КЕА-ИННОВЕЙШН ЭлЭлСи Compositions and methods for controlling accumulation of adipose tissue

Also Published As

Publication number Publication date
US20170044254A1 (en) 2017-02-16
CN106068125B (en) 2021-08-31
US10538586B2 (en) 2020-01-21
DK3083683T3 (en) 2021-01-25
WO2015095354A2 (en) 2015-06-25
HUE067414T2 (en) 2024-10-28
ES2984113T3 (en) 2024-10-28
MX382215B (en) 2025-03-13
JP2017501165A (en) 2017-01-12
CN106068125A (en) 2016-11-02
PL3083683T3 (en) 2021-08-02
JP2018076376A (en) 2018-05-17
MX2016008102A (en) 2017-05-12
AU2014364768A1 (en) 2016-07-07
CN113633768B (en) 2025-11-11
EP3083683B1 (en) 2020-10-28
CA2934004C (en) 2023-07-04
US9771422B2 (en) 2017-09-26
IL246269B (en) 2021-10-31
US10196441B2 (en) 2019-02-05
DK3828203T3 (en) 2024-07-15
JP2019214607A (en) 2019-12-19
CN113633768A (en) 2021-11-12
EP4410833A3 (en) 2024-10-23
IL246269A0 (en) 2016-07-31
ES2846099T3 (en) 2021-07-28
RU2711478C2 (en) 2020-01-17
EP3083683A2 (en) 2016-10-26
JP6633108B2 (en) 2020-01-22
JP6328769B2 (en) 2018-05-23
EP4410833A2 (en) 2024-08-07
US20150166657A1 (en) 2015-06-18
AU2014364768B2 (en) 2020-05-28
HK1225640A1 (en) 2017-09-15
WO2015095354A3 (en) 2015-08-13
EP3828203B1 (en) 2024-04-24
EP3828203A1 (en) 2021-06-02
US20180030133A1 (en) 2018-02-01
CA2934004A1 (en) 2015-06-25
BR112016014042A2 (en) 2017-12-05

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