PL3833786T3 - Konstrukt rekombinowanego kwasu nukleinowego - Google Patents
Konstrukt rekombinowanego kwasu nukleinowegoInfo
- Publication number
- PL3833786T3 PL3833786T3 PL19749727.4T PL19749727T PL3833786T3 PL 3833786 T3 PL3833786 T3 PL 3833786T3 PL 19749727 T PL19749727 T PL 19749727T PL 3833786 T3 PL3833786 T3 PL 3833786T3
- Authority
- PL
- Poland
- Prior art keywords
- nucleic acid
- acid construct
- recombinant nucleic
- recombinant
- construct
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18188489.1A EP3608426A1 (en) | 2018-08-10 | 2018-08-10 | Recombinant nucleic acid construct |
| EP18194023 | 2018-09-12 | ||
| EP18248243 | 2018-12-28 | ||
| PCT/EP2019/071173 WO2020030672A1 (en) | 2018-08-10 | 2019-08-07 | Recombinant nucleic acid construct |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3833786T3 true PL3833786T3 (pl) | 2024-05-06 |
Family
ID=67544260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19749727.4T PL3833786T3 (pl) | 2018-08-10 | 2019-08-07 | Konstrukt rekombinowanego kwasu nukleinowego |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US12516348B2 (pl) |
| EP (1) | EP3833786B1 (pl) |
| JP (1) | JP7663494B2 (pl) |
| KR (1) | KR102811229B1 (pl) |
| CN (1) | CN112567053A (pl) |
| AU (1) | AU2019319035A1 (pl) |
| BR (1) | BR112021002333A2 (pl) |
| DK (1) | DK3833786T5 (pl) |
| ES (1) | ES2970185T3 (pl) |
| FI (1) | FI3833786T3 (pl) |
| HU (1) | HUE066311T2 (pl) |
| IL (1) | IL280157A (pl) |
| MX (1) | MX2021001547A (pl) |
| PL (1) | PL3833786T3 (pl) |
| SG (1) | SG11202100455WA (pl) |
| WO (1) | WO2020030672A1 (pl) |
| ZA (1) | ZA202100242B (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3865122A1 (en) * | 2020-02-11 | 2021-08-18 | Pantherna Therapeutics GmbH | Lipid composition and use thereof for delivery of a therapeutically active agent to endothelium |
| WO2022106072A1 (en) | 2020-11-18 | 2022-05-27 | Aplicacion Y Suministros Textiles, S.A.U. | Textile stone washing process |
| WO2022110010A1 (zh) * | 2020-11-27 | 2022-06-02 | 苏州吉玛基因股份有限公司 | 免疫激活剂、抗原和抗体在制备预防、治疗肿瘤产品中的应用 |
| WO2026033123A1 (en) * | 2024-08-08 | 2026-02-12 | Sanofi Pasteur Inc. | Lipid nanoparticle formulations for mrna delivery |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5318299A (en) | 1998-07-27 | 2000-02-21 | Valentis, Inc. | Anti-angiogenesis plasmids and delivery systems, and methods of making and using the same |
| GB9905498D0 (en) | 1999-03-11 | 1999-05-05 | Glaxo Group Ltd | Expression |
| US7098192B2 (en) * | 1999-04-08 | 2006-08-29 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of STAT3 expression |
| US8039261B2 (en) | 2000-11-17 | 2011-10-18 | Vascular Biogenics Ltd. | Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis |
| MX2011013457A (es) | 2009-06-15 | 2012-05-08 | Biokine Therapeutics Ltd | Polipeptidos que enlazan quimioquina novedosos capaces de inhibir el curso de autoinmunidad, inflamacion y cancer. |
| EP2496700B1 (en) | 2009-11-04 | 2017-03-01 | The University Of British Columbia | Nucleic acid-containing lipid particles and related methods |
| JP6415977B2 (ja) * | 2011-04-15 | 2018-10-31 | ジェネラックス・コーポレイションGenelux Corporation | 弱毒化ワクシニアウイルスのクローン株およびその使用方法 |
| MX372790B (es) | 2013-12-30 | 2020-07-03 | CureVac SE | Moleculas artificiales de acido nucleico. |
| EP3230458B1 (en) * | 2014-12-12 | 2020-02-19 | CureVac AG | Artificial nucleic acid molecules for improved protein expression |
| KR102645398B1 (ko) * | 2015-08-28 | 2024-03-07 | 큐어백 에스이 | 신규 인공 핵산 분자 |
| WO2017100551A1 (en) | 2015-12-09 | 2017-06-15 | Alexion Pharmaceuticals, Inc. | HETEROLOGOUS UTR SEQUENCES FOR ENHANCED mRNA EXPRESSION |
| US20190298657A1 (en) * | 2016-05-18 | 2019-10-03 | Modernatx, Inc. | Polynucleotides Encoding Acyl-CoA Dehydrogenase, Very Long-Chain for the Treatment of Very Long-Chain Acyl-CoA Dehydrogenase Deficiency |
| WO2018115525A1 (en) * | 2016-12-23 | 2018-06-28 | Curevac Ag | Lassa virus vaccine |
-
2019
- 2019-08-07 PL PL19749727.4T patent/PL3833786T3/pl unknown
- 2019-08-07 DK DK19749727.4T patent/DK3833786T5/da active
- 2019-08-07 SG SG11202100455WA patent/SG11202100455WA/en unknown
- 2019-08-07 KR KR1020217006630A patent/KR102811229B1/ko active Active
- 2019-08-07 EP EP19749727.4A patent/EP3833786B1/en active Active
- 2019-08-07 HU HUE19749727A patent/HUE066311T2/hu unknown
- 2019-08-07 JP JP2021531184A patent/JP7663494B2/ja active Active
- 2019-08-07 ES ES19749727T patent/ES2970185T3/es active Active
- 2019-08-07 WO PCT/EP2019/071173 patent/WO2020030672A1/en not_active Ceased
- 2019-08-07 MX MX2021001547A patent/MX2021001547A/es unknown
- 2019-08-07 CN CN201980053544.5A patent/CN112567053A/zh active Pending
- 2019-08-07 FI FIEP19749727.4T patent/FI3833786T3/fi active
- 2019-08-07 AU AU2019319035A patent/AU2019319035A1/en not_active Abandoned
- 2019-08-07 BR BR112021002333-0A patent/BR112021002333A2/pt not_active IP Right Cessation
-
2021
- 2021-01-13 ZA ZA2021/00242A patent/ZA202100242B/en unknown
- 2021-01-13 IL IL280157A patent/IL280157A/en unknown
- 2021-02-10 US US17/173,109 patent/US12516348B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3108670A1 (en) | 2020-02-13 |
| CN112567053A (zh) | 2021-03-26 |
| BR112021002333A2 (pt) | 2021-05-04 |
| WO2020030672A1 (en) | 2020-02-13 |
| ZA202100242B (en) | 2022-05-25 |
| JP2021533821A (ja) | 2021-12-09 |
| MX2021001547A (es) | 2021-06-23 |
| SG11202100455WA (en) | 2021-02-25 |
| DK3833786T3 (da) | 2024-03-04 |
| AU2019319035A1 (en) | 2021-02-04 |
| HUE066311T2 (hu) | 2024-07-28 |
| DK3833786T5 (da) | 2024-08-19 |
| EP3833786A1 (en) | 2021-06-16 |
| IL280157A (en) | 2021-03-01 |
| JP7663494B2 (ja) | 2025-04-16 |
| US20210261980A1 (en) | 2021-08-26 |
| US12516348B2 (en) | 2026-01-06 |
| KR20210044240A (ko) | 2021-04-22 |
| ES2970185T3 (es) | 2024-05-27 |
| FI3833786T3 (fi) | 2024-03-15 |
| KR102811229B1 (ko) | 2025-05-21 |
| EP3833786B1 (en) | 2023-12-27 |
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