PL386174A1 - Sposób wiązania lipopolisacharydów bakteryjnych do fazy stałej - Google Patents
Sposób wiązania lipopolisacharydów bakteryjnych do fazy stałejInfo
- Publication number
- PL386174A1 PL386174A1 PL386174A PL38617408A PL386174A1 PL 386174 A1 PL386174 A1 PL 386174A1 PL 386174 A PL386174 A PL 386174A PL 38617408 A PL38617408 A PL 38617408A PL 386174 A1 PL386174 A1 PL 386174A1
- Authority
- PL
- Poland
- Prior art keywords
- solid phase
- bonding
- lipopolysaccharides
- purification
- subject
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Gram-negative bacteria
- C07K16/1228—Enterobacterales (O), e.g. Citrobacter (G), Serratia (G), Proteus (G), Providencia (G), Morganella (G) or Yersinia (G)
- C07K16/1232—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Przedmiotem wynalazku jest sposób otrzymywania złóż do chromatografii powinowactwa ze związanymi w niekowalencyjny i trwały sposób cząsteczkami lipopolisacharydu bakteryjnego. Uzyskane według wynalazku złoże może być wykorzystane w chromatografii powinowactwa do oczyszczania przeciwciał przeciwko lipopolisacharydom. Szczególnie przydatne jest do oczyszczania przeciwciał skierowanych przeciwko labilnym epitopom lipopolisacharydów, które ulegały degradacji w dotąd używanych warunkach kowalencyjnego wiązania cząsteczek lipopolisacharydu do fazy stałej.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL386174A PL217758B1 (pl) | 2008-09-29 | 2008-09-29 | Sposób otrzymywania złoża do chromatografii powinowactwa i zastosowanie otrzymanego tym sposobem złoża |
| US13/059,539 US8426221B2 (en) | 2008-09-29 | 2009-09-27 | Method of binding bacterial lipopolysaccharides to a solid phase |
| PCT/PL2009/050026 WO2010036133A1 (en) | 2008-09-29 | 2009-09-27 | A method of binding bacterial lipopolysaccharides to a solid phase |
| ES09752002.7T ES2560779T3 (es) | 2008-09-29 | 2009-09-27 | Un procedimiento de unión de lipopolisacáridos bacterianos a una fase sólida |
| EP09752002.7A EP2328927B1 (en) | 2008-09-29 | 2009-09-27 | A method of binding bacterial lipopolysaccharides to a solid phase |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL386174A PL217758B1 (pl) | 2008-09-29 | 2008-09-29 | Sposób otrzymywania złoża do chromatografii powinowactwa i zastosowanie otrzymanego tym sposobem złoża |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL386174A1 true PL386174A1 (pl) | 2010-04-12 |
| PL217758B1 PL217758B1 (pl) | 2014-08-29 |
Family
ID=41531725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL386174A PL217758B1 (pl) | 2008-09-29 | 2008-09-29 | Sposób otrzymywania złoża do chromatografii powinowactwa i zastosowanie otrzymanego tym sposobem złoża |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8426221B2 (pl) |
| EP (1) | EP2328927B1 (pl) |
| ES (1) | ES2560779T3 (pl) |
| PL (1) | PL217758B1 (pl) |
| WO (1) | WO2010036133A1 (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2848223B1 (fr) * | 2002-12-09 | 2005-02-25 | Centre Nat Rech Scient | Nouveau procede d'isolement des endotoxines. |
| WO2017042303A1 (en) * | 2015-09-08 | 2017-03-16 | Danmarks Tekniske Universitet | Binding of hydrophobic antigens to surfaces |
| WO2023007456A1 (en) * | 2021-07-30 | 2023-02-02 | Biovetika Spółka Z Ograniczoną Odpowiedzialnością | A method for producing complexes of proteins with bacterial lipopolysaccharides, the use thereof, a vaccine comprising an lps/protein immunogenic complex and a method for producing the vaccine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2660197B1 (fr) | 1990-04-03 | 1994-10-21 | Fondation Nale Transfusion San | Anticorps purifies specifiquement diriges contre les lipopolysaccharides (lps) des bacteries gram negatif. |
| HK1043622A1 (zh) | 1998-12-15 | 2002-09-20 | Exiqon A/S | 報道基因基團導入細菌脂多醣衍生的碳水化合物及隨後使該衍生物偶合至固體表面上的方法 |
-
2008
- 2008-09-29 PL PL386174A patent/PL217758B1/pl unknown
-
2009
- 2009-09-27 WO PCT/PL2009/050026 patent/WO2010036133A1/en not_active Ceased
- 2009-09-27 EP EP09752002.7A patent/EP2328927B1/en not_active Not-in-force
- 2009-09-27 US US13/059,539 patent/US8426221B2/en not_active Expired - Fee Related
- 2009-09-27 ES ES09752002.7T patent/ES2560779T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20110230648A1 (en) | 2011-09-22 |
| ES2560779T3 (es) | 2016-02-22 |
| EP2328927B1 (en) | 2015-12-23 |
| US8426221B2 (en) | 2013-04-23 |
| EP2328927A1 (en) | 2011-06-08 |
| WO2010036133A1 (en) | 2010-04-01 |
| PL217758B1 (pl) | 2014-08-29 |
| ES2560779T8 (es) | 2016-03-08 |
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