PL3880168T3 - Aqueous paediatric retinol formulations - Google Patents

Aqueous paediatric retinol formulations

Info

Publication number
PL3880168T3
PL3880168T3 PL19808595.3T PL19808595T PL3880168T3 PL 3880168 T3 PL3880168 T3 PL 3880168T3 PL 19808595 T PL19808595 T PL 19808595T PL 3880168 T3 PL3880168 T3 PL 3880168T3
Authority
PL
Poland
Prior art keywords
paediatric
aqueous
retinol formulations
retinol
formulations
Prior art date
Application number
PL19808595.3T
Other languages
Polish (pl)
Inventor
Philipp NOVAK
Christian Seliger
Jochen Bauer
Original Assignee
Orphanix Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orphanix Gmbh filed Critical Orphanix Gmbh
Publication of PL3880168T3 publication Critical patent/PL3880168T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL19808595.3T 2018-11-26 2019-11-26 Aqueous paediatric retinol formulations PL3880168T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18208340 2018-11-26
PCT/EP2019/082510 WO2020109272A1 (en) 2018-11-26 2019-11-26 Aqueous paediatric retinol formulations

Publications (1)

Publication Number Publication Date
PL3880168T3 true PL3880168T3 (en) 2024-12-16

Family

ID=64477035

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19808595.3T PL3880168T3 (en) 2018-11-26 2019-11-26 Aqueous paediatric retinol formulations

Country Status (18)

Country Link
US (1) US12576046B2 (en)
EP (2) EP4483870B1 (en)
JP (1) JP7774292B2 (en)
KR (1) KR102887267B1 (en)
CN (1) CN113056260A (en)
AU (1) AU2019386241B2 (en)
BR (1) BR112021009781A2 (en)
CA (1) CA3117767A1 (en)
DK (1) DK3880168T3 (en)
ES (2) ES2988763T3 (en)
FI (1) FI3880168T3 (en)
IL (1) IL282833A (en)
MX (1) MX2021005950A (en)
PL (1) PL3880168T3 (en)
PT (1) PT3880168T (en)
SG (1) SG11202104149VA (en)
WO (1) WO2020109272A1 (en)
ZA (1) ZA202104321B (en)

Family Cites Families (43)

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US3708583A (en) 1970-04-03 1973-01-02 Vitamin Premixers Of Omaha Inc Stabilized vitamin a additive
GB1464797A (en) 1973-08-02 1977-02-16 American Cyanamid Co Injectable liquid vitamin preparation
US4022913A (en) 1973-09-13 1977-05-10 Hoffmann-La Roche Inc. High potency vitamin A compositions
DE2526938C2 (en) 1975-02-14 1982-04-22 F. Hoffmann-La Roche & Co. AG, 4002 Basel Vitamin preparations
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AU5861396A (en) 1995-05-19 1996-11-29 Abbott Laboratories Stable aqueous formulations of 1alpha,25-dihydroxycholecalci ferol for parenteral administration
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US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US5935556A (en) 1998-07-30 1999-08-10 The Procter & Gamble Company Sunscreen compositions
PL356968A1 (en) * 1999-04-13 2004-07-12 Leo Pharmaceutical Products Ltd.A/S Solubilized pharmaceutical composition for parenteral administration
KR20010055736A (en) 1999-12-13 2001-07-04 이규현 Composition of microemulsified propofol
JP3903061B2 (en) 2003-12-24 2007-04-11 株式会社Lttバイオファーマ Nanoparticles containing drug, method for producing the same, and preparation for parenteral administration comprising the nanoparticles
RU2294651C1 (en) 2005-05-31 2007-03-10 Виктор Александрович Быков Method for production of water-soluble preparation enriched with vitamin components, obtained preparation (variants)
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CN104706643A (en) * 2013-12-16 2015-06-17 天津迈迪瑞康生物医药科技有限公司 Fat-soluble vitamin injection concentrated solution (I), preparation method and application thereof
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Also Published As

Publication number Publication date
EP4483870A3 (en) 2025-04-02
SG11202104149VA (en) 2021-05-28
CA3117767A1 (en) 2020-06-04
ES3064237T3 (en) 2026-04-23
NZ775488A (en) 2025-05-02
DK3880168T3 (en) 2024-10-28
EP4483870C0 (en) 2026-02-18
ES2988763T3 (en) 2024-11-21
KR20210096093A (en) 2021-08-04
FI3880168T3 (en) 2024-10-31
AU2019386241A1 (en) 2021-05-27
EP3880168B1 (en) 2024-08-21
CN113056260A (en) 2021-06-29
WO2020109272A1 (en) 2020-06-04
JP7774292B2 (en) 2025-11-21
EP4483870B1 (en) 2026-02-18
AU2019386241B2 (en) 2024-10-17
JP2022509196A (en) 2022-01-20
EP4483870A2 (en) 2025-01-01
MX2021005950A (en) 2021-07-06
KR102887267B1 (en) 2025-11-17
ZA202104321B (en) 2023-10-25
IL282833A (en) 2021-06-30
EP3880168A1 (en) 2021-09-22
US12576046B2 (en) 2026-03-17
US20220000802A1 (en) 2022-01-06
BR112021009781A2 (en) 2021-08-17
PT3880168T (en) 2024-10-07

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