PL3897655T3 - 3beta-(benzyloksy)-17alfa-metylo-pregn-5-en-20-on do stosowania w leczeniu zaburzeń poznawczych - Google Patents

3beta-(benzyloksy)-17alfa-metylo-pregn-5-en-20-on do stosowania w leczeniu zaburzeń poznawczych

Info

Publication number
PL3897655T3
PL3897655T3 PL19831675.4T PL19831675T PL3897655T3 PL 3897655 T3 PL3897655 T3 PL 3897655T3 PL 19831675 T PL19831675 T PL 19831675T PL 3897655 T3 PL3897655 T3 PL 3897655T3
Authority
PL
Poland
Prior art keywords
17alpha
3beta
pregn
benzyloxy
methyl
Prior art date
Application number
PL19831675.4T
Other languages
English (en)
Inventor
Pier-Vincenzo Piazza
Sandy FABRE
Stéphanie MONLEZUN
Mathilde METNA
Monique VALLEE
Jean-Michel REVEST
Daniela COTA
Giovanni Marsicano
Aline MARIGHETTO
Andrés OZAITA
Rafael MALDONADO
Original Assignee
Aelis Farma
Universite de Bordeaux
Institut National De La Sante Et De La Recherche Medicale (Inserm)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aelis Farma, Universite de Bordeaux, Institut National De La Sante Et De La Recherche Medicale (Inserm) filed Critical Aelis Farma
Publication of PL3897655T3 publication Critical patent/PL3897655T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/009Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by only one oxygen atom doubly bound
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL19831675.4T 2018-12-18 2019-12-18 3beta-(benzyloksy)-17alfa-metylo-pregn-5-en-20-on do stosowania w leczeniu zaburzeń poznawczych PL3897655T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18306716.4A EP3669876A1 (en) 2018-12-18 2018-12-18 3béta-(benzyloxy)-17alpha-methyl-pregn-5-en-20-one for use in the treatment of cognitive disorders
PCT/EP2019/085927 WO2020127468A1 (en) 2018-12-18 2019-12-18 3β-(BENZYLOXY)-17α-METHYL-PREGN-5-EN-20-ONE FOR USE IN THE TREATMENT OF COGNITIVE DISORDERS

Publications (1)

Publication Number Publication Date
PL3897655T3 true PL3897655T3 (pl) 2025-01-13

Family

ID=65278139

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19831675.4T PL3897655T3 (pl) 2018-12-18 2019-12-18 3beta-(benzyloksy)-17alfa-metylo-pregn-5-en-20-on do stosowania w leczeniu zaburzeń poznawczych

Country Status (25)

Country Link
EP (2) EP3669876A1 (pl)
JP (1) JP7515480B2 (pl)
KR (1) KR102845328B1 (pl)
CN (1) CN113260366B (pl)
AU (1) AU2019409912B2 (pl)
BR (1) BR112021011654A2 (pl)
CA (1) CA3118210C (pl)
CL (1) CL2021001458A1 (pl)
DK (1) DK3897655T3 (pl)
ES (1) ES2987823T3 (pl)
FI (1) FI3897655T3 (pl)
HR (1) HRP20241376T1 (pl)
HU (1) HUE068626T2 (pl)
IL (1) IL284032B2 (pl)
LT (1) LT3897655T (pl)
MA (1) MA54518B1 (pl)
MD (1) MD3897655T2 (pl)
MX (1) MX2021006904A (pl)
PL (1) PL3897655T3 (pl)
PT (1) PT3897655T (pl)
RS (1) RS66013B1 (pl)
SI (1) SI3897655T1 (pl)
SM (1) SMT202400425T1 (pl)
WO (1) WO2020127468A1 (pl)
ZA (1) ZA202103284B (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024085245A1 (ja) 2022-10-21 2024-04-25 国立大学法人高知大学 術後せん妄の抑制薬

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE453620T1 (de) * 2003-05-01 2010-01-15 Vernalis Res Ltd Azetidincarboxamid-derivate zur verwendung zur behandlung von cb1-rezeptor-vermittelten krankheiten
EP2044029B1 (en) * 2006-07-14 2011-01-26 Pfizer Products Inc. Tartrate salt of (7s)-7-[(5-fluoro-2-methyl-benzyl)oxy]-2-[(2r)-2-methylpiperazin-1-yl]-6,7-dihydro-5h-cyclopenta[b]pyridine
CN101790521A (zh) * 2007-06-28 2010-07-28 英特维特国际股份有限公司 作为cb1拮抗剂的取代哌嗪
PT2709631T (pt) * 2011-05-20 2017-04-19 Inserm - Inst Nat De La Santé Et De La Rech Médicale Antagonistas de receptor de cb1
DK2925770T3 (en) * 2012-11-28 2017-04-10 Univ Bordeaux 3- (4'-SUBSTITUTED) -BENZYL-ETHER DERIVATIVES OF PREGNENOLONE
SMT202000164T1 (it) * 2013-03-19 2020-05-08 Univ Pompeu Fabra Antagonisti del recettore cannabinoide cb1 per uso nel trattamento di malattie associate con anomalie dendritiche neuronali

Also Published As

Publication number Publication date
EP3669876A1 (en) 2020-06-24
LT3897655T (lt) 2024-10-10
WO2020127468A1 (en) 2020-06-25
IL284032B2 (en) 2025-05-01
CA3118210C (en) 2024-05-21
US20220017562A1 (en) 2022-01-20
JP7515480B2 (ja) 2024-07-12
RS66013B1 (sr) 2024-10-31
SI3897655T1 (sl) 2025-04-30
ZA202103284B (en) 2024-09-25
AU2019409912A1 (en) 2021-05-27
EP3897655A1 (en) 2021-10-27
IL284032A (en) 2021-08-31
PT3897655T (pt) 2024-10-14
CA3118210A1 (en) 2020-06-25
HUE068626T2 (hu) 2025-01-28
ES2987823T3 (es) 2024-11-18
KR102845328B1 (ko) 2025-08-12
SMT202400425T1 (it) 2024-11-15
KR20210124962A (ko) 2021-10-15
IL284032B1 (en) 2025-01-01
HRP20241376T1 (hr) 2024-12-20
BR112021011654A2 (pt) 2021-09-08
CL2021001458A1 (es) 2022-01-21
DK3897655T3 (da) 2024-09-23
AU2019409912B2 (en) 2025-02-20
MD3897655T2 (ro) 2024-12-31
EP3897655B1 (en) 2024-07-17
FI3897655T3 (fi) 2024-09-17
CN113260366B (zh) 2024-03-08
JP2022515373A (ja) 2022-02-18
MA54518A (fr) 2022-02-16
MA54518B1 (fr) 2024-11-29
MX2021006904A (es) 2021-09-30
CN113260366A (zh) 2021-08-13
AU2019409912A8 (en) 2021-06-17

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