PL394619A1 - Sposób proteolizy, peptydaza, kompozycja do stosowania jako srodek bakteriostatyczny lub bakteriobójczy, zestaw oraz zastosowania aktywnej formy LytM z S. aureus lub jej pochodnej - Google Patents

Sposób proteolizy, peptydaza, kompozycja do stosowania jako srodek bakteriostatyczny lub bakteriobójczy, zestaw oraz zastosowania aktywnej formy LytM z S. aureus lub jej pochodnej

Info

Publication number
PL394619A1
PL394619A1 PL394619A PL39461911A PL394619A1 PL 394619 A1 PL394619 A1 PL 394619A1 PL 394619 A PL394619 A PL 394619A PL 39461911 A PL39461911 A PL 39461911A PL 394619 A1 PL394619 A1 PL 394619A1
Authority
PL
Poland
Prior art keywords
lytm
bactericide
peptidase
proteolysis
aureus
Prior art date
Application number
PL394619A
Other languages
English (en)
Inventor
Izabela Sabala
Matthias Bochtler
Original Assignee
Miedzynarodowy Instytut Biologii Molekularnej I Komórkowej
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miedzynarodowy Instytut Biologii Molekularnej I Komórkowej filed Critical Miedzynarodowy Instytut Biologii Molekularnej I Komórkowej
Priority to PL394619A priority Critical patent/PL394619A1/pl
Priority to ES12722933.4T priority patent/ES2537701T3/es
Priority to AU2012246763A priority patent/AU2012246763B2/en
Priority to JP2014506359A priority patent/JP6022544B2/ja
Priority to EP12722933.4A priority patent/EP2699254B1/en
Priority to PL12722933T priority patent/PL2699254T3/pl
Priority to PCT/PL2012/000026 priority patent/WO2012144912A1/en
Priority to CA2833335A priority patent/CA2833335C/en
Priority to DK12722933.4T priority patent/DK2699254T3/da
Publication of PL394619A1 publication Critical patent/PL394619A1/pl
Priority to US14/056,432 priority patent/US9487771B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24075—Lysostaphin (3.4.24.75)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Environmental Sciences (AREA)
  • Virology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Enzymes And Modification Thereof (AREA)
PL394619A 2011-04-19 2011-04-19 Sposób proteolizy, peptydaza, kompozycja do stosowania jako srodek bakteriostatyczny lub bakteriobójczy, zestaw oraz zastosowania aktywnej formy LytM z S. aureus lub jej pochodnej PL394619A1 (pl)

Priority Applications (10)

Application Number Priority Date Filing Date Title
PL394619A PL394619A1 (pl) 2011-04-19 2011-04-19 Sposób proteolizy, peptydaza, kompozycja do stosowania jako srodek bakteriostatyczny lub bakteriobójczy, zestaw oraz zastosowania aktywnej formy LytM z S. aureus lub jej pochodnej
ES12722933.4T ES2537701T3 (es) 2011-04-19 2012-04-18 Un método de hidrólisis de péptidos, uso de una composición como agente bacteriostático y bactericida y los usos de la forma activa de LytM de S. aureus
AU2012246763A AU2012246763B2 (en) 2011-04-19 2012-04-18 A method of peptide hydrolysis, peptidase, the composition for use as a bacteriostatic and bactericidal agent, a kit and the uses of the active form of LytM from S. aureus or derivatives thereof
JP2014506359A JP6022544B2 (ja) 2011-04-19 2012-04-18 ペプチド加水分解の方法、ペプチダーゼ、静菌剤および殺菌剤としての使用のための組成物、黄色ブドウ球菌からのＬｙｔＭの活性型またはその誘導体のキットおよび使用
EP12722933.4A EP2699254B1 (en) 2011-04-19 2012-04-18 A method of peptide hydrolysis, use of a composition as a bacteriostatic and bactericidal agent and the uses of the active form of lytm from s. aureus
PL12722933T PL2699254T3 (pl) 2011-04-19 2012-04-18 Sposób proteolizy, zastosowanie kompozycji jako środka bakteriostatycznego lub bakteriobójczego oraz zastosowania aktywnej formy LytM z S. aureus
PCT/PL2012/000026 WO2012144912A1 (en) 2011-04-19 2012-04-18 A method of peptide hydrolysis, peptidase, the composition for use as a bacteriostatic and bactericidal agent, a kit and the uses of the active form of lytm from s. aureus or derivatives thereof
CA2833335A CA2833335C (en) 2011-04-19 2012-04-18 A method of peptide hydrolysis, peptidase, the composition for use as a bacteriostatic and bactericidal agent, a kit and the uses of the active form of lytm from s. aureus or derivatives thereof
DK12722933.4T DK2699254T3 (da) 2011-04-19 2012-04-18 Fremgangsmåde til peptidhydrolyse, anvendelse af en sammensætning som et bakteriostatisk og bakteriedræbende mide4l og anvendelserne af den aktive form af LytM fra S. Aureus
US14/056,432 US9487771B2 (en) 2011-04-19 2013-10-17 Method of peptide hydrolysis, peptidase, the composition for use as a bacteriostatic and bactericidal agent, a kit and the uses of the active form of LytM from S. aureus or derivatives thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL394619A PL394619A1 (pl) 2011-04-19 2011-04-19 Sposób proteolizy, peptydaza, kompozycja do stosowania jako srodek bakteriostatyczny lub bakteriobójczy, zestaw oraz zastosowania aktywnej formy LytM z S. aureus lub jej pochodnej

Publications (1)

Publication Number Publication Date
PL394619A1 true PL394619A1 (pl) 2012-10-22

Family

ID=46147662

Family Applications (2)

Application Number Title Priority Date Filing Date
PL394619A PL394619A1 (pl) 2011-04-19 2011-04-19 Sposób proteolizy, peptydaza, kompozycja do stosowania jako srodek bakteriostatyczny lub bakteriobójczy, zestaw oraz zastosowania aktywnej formy LytM z S. aureus lub jej pochodnej
PL12722933T PL2699254T3 (pl) 2011-04-19 2012-04-18 Sposób proteolizy, zastosowanie kompozycji jako środka bakteriostatycznego lub bakteriobójczego oraz zastosowania aktywnej formy LytM z S. aureus

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL12722933T PL2699254T3 (pl) 2011-04-19 2012-04-18 Sposób proteolizy, zastosowanie kompozycji jako środka bakteriostatycznego lub bakteriobójczego oraz zastosowania aktywnej formy LytM z S. aureus

Country Status (9)

Country Link
US (1) US9487771B2 (pl)
EP (1) EP2699254B1 (pl)
JP (1) JP6022544B2 (pl)
AU (1) AU2012246763B2 (pl)
CA (1) CA2833335C (pl)
DK (1) DK2699254T3 (pl)
ES (1) ES2537701T3 (pl)
PL (2) PL394619A1 (pl)
WO (1) WO2012144912A1 (pl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111329830A (zh) * 2020-03-06 2020-06-26 重庆雅素生物科技有限公司 一种微球菌属细菌发酵溶胞液的获取方法及其在抗衰老中的应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL243304B1 (pl) 2021-07-09 2023-07-31 Miedzynarodowy Inst Biologii Molekularnej I Komorkowej W Warszawie Hydrolaza peptydoglikanowa, kompozycje ją obejmujące, jej zastosowania oraz sposób hydrolizy ją wykorzystujący
CN115851667B (zh) * 2023-01-17 2026-01-30 陕西科技大学 一种调控重组核酸酶活性的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US5270176A (en) * 1987-11-20 1993-12-14 Hoechst Aktiengesellschaft Method for the selective cleavage of fusion proteins with lysostaphin
WO2007113499A1 (en) * 2006-03-31 2007-10-11 The University Court Of The University Of St Andrews Anti-microbial compositions comprising a cationic peptide and a glycylglycine endopeptidase
CN103436507B (zh) * 2006-05-05 2016-04-20 冈戈根股份有限公司 噬菌体衍生的抗微生物活性剂
GB0902316D0 (en) * 2009-02-12 2009-04-01 Univ Nottingham Pathogen detector assay, method and kit
US8932809B2 (en) * 2010-01-19 2015-01-13 Opgen, Inc. Methods and kits for isolating nucleic acid from an organism

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111329830A (zh) * 2020-03-06 2020-06-26 重庆雅素生物科技有限公司 一种微球菌属细菌发酵溶胞液的获取方法及其在抗衰老中的应用
CN111329830B (zh) * 2020-03-06 2022-08-30 重庆雅素生物科技有限公司 一种微球菌属细菌发酵溶胞液的获取方法及其在抗衰老中的应用

Also Published As

Publication number Publication date
DK2699254T3 (da) 2015-05-11
EP2699254B1 (en) 2015-04-22
EP2699254A1 (en) 2014-02-26
AU2012246763B2 (en) 2015-05-21
WO2012144912A8 (en) 2013-11-14
WO2012144912A1 (en) 2012-10-26
US9487771B2 (en) 2016-11-08
AU2012246763A1 (en) 2013-11-21
PL2699254T3 (pl) 2015-08-31
CA2833335A1 (en) 2012-10-26
ES2537701T3 (es) 2015-06-11
JP6022544B2 (ja) 2016-11-09
JP2014514319A (ja) 2014-06-19
US20140044698A1 (en) 2014-02-13
CA2833335C (en) 2016-11-15

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