PL3982924T3 - Mieszanina ekstraktów roślinnych do stosowania w profilaktyce i/lub leczeniu przewlekłych chorób zapalnych jelit - Google Patents

Mieszanina ekstraktów roślinnych do stosowania w profilaktyce i/lub leczeniu przewlekłych chorób zapalnych jelit

Info

Publication number
PL3982924T3
PL3982924T3 PL20734655.2T PL20734655T PL3982924T3 PL 3982924 T3 PL3982924 T3 PL 3982924T3 PL 20734655 T PL20734655 T PL 20734655T PL 3982924 T3 PL3982924 T3 PL 3982924T3
Authority
PL
Poland
Prior art keywords
prevention
treatment
inflammatory bowel
plant extract
chronic inflammatory
Prior art date
Application number
PL20734655.2T
Other languages
English (en)
Inventor
Sébastien PELTIER
Pascal SIRVENT
Yolanda OTERO
Original Assignee
Valbiotis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valbiotis filed Critical Valbiotis
Publication of PL3982924T3 publication Critical patent/PL3982924T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL20734655.2T 2019-06-11 2020-06-11 Mieszanina ekstraktów roślinnych do stosowania w profilaktyce i/lub leczeniu przewlekłych chorób zapalnych jelit PL3982924T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1906165A FR3097122B1 (fr) 2019-06-11 2019-06-11 Melange d’extraits de plantes pour son utilisation dans la prevention et/ou le traitement des maladies chroniques inflammatoires de l’intestin
PCT/EP2020/066164 WO2020249657A1 (fr) 2019-06-11 2020-06-11 Melange d'extraits de plantes pour son utilisation dans la prevention et/ou le traitement des maladies chroniques inflammatoires de l'intestin

Publications (1)

Publication Number Publication Date
PL3982924T3 true PL3982924T3 (pl) 2023-12-27

Family

ID=67441498

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20734655.2T PL3982924T3 (pl) 2019-06-11 2020-06-11 Mieszanina ekstraktów roślinnych do stosowania w profilaktyce i/lub leczeniu przewlekłych chorób zapalnych jelit

Country Status (23)

Country Link
US (1) US20220257685A1 (pl)
EP (1) EP3982924B1 (pl)
JP (1) JP2022535964A (pl)
KR (1) KR20220027950A (pl)
CN (1) CN114502141A (pl)
AU (1) AU2020292586A1 (pl)
BR (1) BR112021025056A2 (pl)
CA (1) CA3142860A1 (pl)
CL (1) CL2021003291A1 (pl)
DK (1) DK3982924T3 (pl)
ES (1) ES2963639T3 (pl)
FI (1) FI3982924T3 (pl)
FR (1) FR3097122B1 (pl)
HR (1) HRP20231360T1 (pl)
HU (1) HUE064209T2 (pl)
IL (1) IL288882A (pl)
MX (1) MX2021015256A (pl)
PH (1) PH12021553108A1 (pl)
PL (1) PL3982924T3 (pl)
PT (1) PT3982924T (pl)
SI (1) SI3982924T1 (pl)
WO (1) WO2020249657A1 (pl)
ZA (1) ZA202110225B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202100002735A1 (it) * 2021-02-08 2022-08-08 Phytoitalia Srl Metodo di estrazione e arricchimento di flavonoidi monoglicosilati da chrysanthellum indicum per il trattamento di patologie poliartritiche su base infiammatoria, per l'uso in dispositivi cosmetici, nutraceutici, medici e applicazioni farmaceutiche
CN115120604A (zh) * 2021-03-24 2022-09-30 陕西凤丹正元生物科技有限公司 芹菜素7-o-葡萄糖苷作为降尿酸和痛风性关节炎制剂的应用
CN114903910A (zh) * 2022-05-09 2022-08-16 淮阴师范学院 芹菜素-7-O-β-D-葡萄糖苷在制备炎症性肠病治疗药物中的应用
CN115645429B (zh) * 2022-12-12 2023-05-16 汤臣倍健股份有限公司 一种花色苷组合物及其应用
CN116942689A (zh) * 2023-07-28 2023-10-27 陕西秦岭特色生物资源产业技术研究院有限公司 木犀草苷在制备治疗mtx诱导的肠道炎症药物中的应用
SE547351C2 (en) * 2023-09-13 2025-07-08 Lewa Of Sweden Ab Permeable pouch comprising a moist non-tobacco composition
CN117017871B (zh) * 2023-09-19 2026-04-03 广州市科能化妆品科研有限公司 一种发用防脱组合物及其制备方法和应用
CN118275573B (zh) * 2024-04-07 2025-12-09 四川新绿色药业科技发展有限公司 一种檀香药材、饮片、标准汤剂、配方颗粒含量的测定方法
EP4635300A1 (en) * 2024-04-18 2025-10-22 ITALFEED S.r.l. - Società Unipersonale Compositions based on plant ingredients, probiotics and immunoglobulins and their use in the zootechnical field
CN121731292A (zh) * 2026-02-27 2026-03-27 浙江大学医学院附属第二医院 菜蓟苦素在治疗急性呼吸窘迫综合征和抑制nlrp3炎症小体中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744161A (en) * 1995-02-24 1998-04-28 Sabinsa Corporation Use of piperine as a bioavailability enhancer
CN1646093A (zh) * 2002-02-13 2005-07-27 克雷农业公司 治疗炎症和与aids关联的神经紊乱的方法和组合物
JP4585227B2 (ja) * 2003-05-12 2010-11-24 株式会社ファンケル 痩身用キット
ITMI20051347A1 (it) * 2005-07-14 2007-01-15 Indena Spa Estratti di cynara scolimus loro uso e formulazioni che li contengono
WO2013070898A1 (en) * 2011-11-09 2013-05-16 Master Holdings Llc Extracts
CA2916972A1 (en) * 2013-07-18 2015-01-22 Amino Up Chemical Co., Ltd. A composition having a prebiotic effect
JP6727126B2 (ja) * 2013-08-20 2020-07-22 シュバイツァー モウドゥイ インターナショナル インコーポレイテッド 植物を含む、医薬用途、化粧用途、着色用途、又は皮膚用途のための製品
FR3027228B1 (fr) * 2014-10-20 2016-12-09 Valbiotis Composition comprenant un melange d'extraits vegetaux et utilisation pour agir sur le metabolisme glucidique et/ou lipidique
WO2016156527A1 (fr) * 2015-03-31 2016-10-06 International Nutrition Research Company Composition pour le traitement d'un etat metabolique pathogene du microbiote intestinal et des maladies derivees
FR3042413B1 (fr) * 2015-10-20 2019-07-12 Valbiotis Composition comprenant un melange de molecules extraites de chrysanthellum indicum et de cynara scolymus et utilisation pour agir sur le metabolisme glucidique et/ou lipidique
FR3042411B1 (fr) * 2015-10-20 2019-07-12 Valbiotis Composition comprenant un melange de molecules particulieres et utilisation pour agir sur le metabolisme glucidique et/ou lipidique
KR20190079641A (ko) * 2016-10-27 2019-07-05 엔에스이 프로덕츠, 인크. 장 건강 촉진 조성물

Also Published As

Publication number Publication date
BR112021025056A2 (pt) 2022-02-22
HUE064209T2 (hu) 2024-03-28
EP3982924A1 (fr) 2022-04-20
SI3982924T1 (sl) 2023-12-29
FI3982924T3 (en) 2023-11-02
KR20220027950A (ko) 2022-03-08
ZA202110225B (en) 2022-07-27
HRP20231360T1 (hr) 2024-02-16
AU2020292586A1 (en) 2022-01-20
CL2021003291A1 (es) 2023-02-03
CA3142860A1 (fr) 2020-12-17
PH12021553108A1 (en) 2022-08-01
DK3982924T3 (da) 2023-10-30
JP2022535964A (ja) 2022-08-10
FR3097122B1 (fr) 2021-06-18
FR3097122A1 (fr) 2020-12-18
ES2963639T3 (es) 2024-04-01
IL288882A (en) 2022-02-01
US20220257685A1 (en) 2022-08-18
WO2020249657A1 (fr) 2020-12-17
EP3982924B1 (fr) 2023-07-26
CN114502141A (zh) 2022-05-13
PT3982924T (pt) 2023-11-29
MX2021015256A (es) 2022-04-12

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