PL3986419T3 - BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS - Google Patents
BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONSInfo
- Publication number
- PL3986419T3 PL3986419T3 PL20827883.8T PL20827883T PL3986419T3 PL 3986419 T3 PL3986419 T3 PL 3986419T3 PL 20827883 T PL20827883 T PL 20827883T PL 3986419 T3 PL3986419 T3 PL 3986419T3
- Authority
- PL
- Poland
- Prior art keywords
- acid derivatives
- boronic acid
- therapeutic applications
- therapeutic
- applications
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962863752P | 2019-06-19 | 2019-06-19 | |
| PCT/US2020/038171 WO2020257306A1 (en) | 2019-06-19 | 2020-06-17 | Boronic acid derivatives and therapeutic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3986419T3 true PL3986419T3 (en) | 2025-09-08 |
Family
ID=74040882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20827883.8T PL3986419T3 (en) | 2019-06-19 | 2020-06-17 | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230144152A1 (en) |
| EP (2) | EP3986419B1 (en) |
| CN (1) | CN114340639A (en) |
| DK (1) | DK3986419T3 (en) |
| ES (1) | ES3036963T3 (en) |
| FI (1) | FI3986419T3 (en) |
| HR (1) | HRP20250815T1 (en) |
| HU (1) | HUE072159T2 (en) |
| LT (1) | LT3986419T (en) |
| PL (1) | PL3986419T3 (en) |
| PT (1) | PT3986419T (en) |
| SI (1) | SI3986419T1 (en) |
| WO (1) | WO2020257306A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX389349B (en) | 2016-06-30 | 2025-03-20 | Qpex Biopharma Inc | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES. |
| EP3781576B1 (en) | 2018-04-20 | 2024-06-12 | Qpex Biopharma, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| AU2021266715A1 (en) | 2020-05-05 | 2022-11-17 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis, polymorphic forms, and therapeutic uses thereof |
| JP2024512793A (en) * | 2021-04-05 | 2024-03-19 | キューペックス バイオファーマ, インコーポレイテッド | Ceftibuten dosing regimen |
| JP2026504522A (en) * | 2023-02-08 | 2026-02-05 | キューペックス バイオファーマ, インコーポレイテッド | Methods for determining siderophore beta-lactam susceptibility |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4783443A (en) | 1986-03-03 | 1988-11-08 | The University Of Chicago | Amino acyl cephalosporin derivatives |
| US7271186B1 (en) | 2002-12-09 | 2007-09-18 | Northwestern University | Nanomolar β-lactamase inhibitors |
| CA2705393A1 (en) | 2007-11-13 | 2009-05-22 | Protez Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| EP3139930B1 (en) * | 2014-05-05 | 2024-08-14 | Melinta Therapeutics, Inc. | Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof |
| AU2015264418A1 (en) | 2014-05-19 | 2016-11-10 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| WO2017100537A1 (en) * | 2015-12-10 | 2017-06-15 | VenatoRx Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| MX389349B (en) * | 2016-06-30 | 2025-03-20 | Qpex Biopharma Inc | BORONIC ACID DERIVATIVES AND THEIR THERAPEUTIC USES. |
| WO2018075084A1 (en) | 2016-10-20 | 2018-04-26 | Symbol Technologies, Llc | Mobile device with edge activation |
| US11286270B2 (en) * | 2017-10-11 | 2022-03-29 | Qpex Biopharma, Inc. | Boronic acid derivatives and synthesis thereof |
-
2020
- 2020-06-17 EP EP20827883.8A patent/EP3986419B1/en active Active
- 2020-06-17 ES ES20827883T patent/ES3036963T3/en active Active
- 2020-06-17 SI SI202030640T patent/SI3986419T1/en unknown
- 2020-06-17 HR HRP20250815TT patent/HRP20250815T1/en unknown
- 2020-06-17 LT LTEPPCT/US2020/038171T patent/LT3986419T/en unknown
- 2020-06-17 US US17/619,752 patent/US20230144152A1/en active Pending
- 2020-06-17 DK DK20827883.8T patent/DK3986419T3/en active
- 2020-06-17 FI FIEP20827883.8T patent/FI3986419T3/en active
- 2020-06-17 PT PT208278838T patent/PT3986419T/en unknown
- 2020-06-17 PL PL20827883.8T patent/PL3986419T3/en unknown
- 2020-06-17 HU HUE20827883A patent/HUE072159T2/en unknown
- 2020-06-17 CN CN202080059598.5A patent/CN114340639A/en active Pending
- 2020-06-17 EP EP25175312.5A patent/EP4599892A3/en active Pending
- 2020-06-17 WO PCT/US2020/038171 patent/WO2020257306A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3986419A1 (en) | 2022-04-27 |
| EP3986419A4 (en) | 2023-07-12 |
| HUE072159T2 (en) | 2025-10-28 |
| EP4599892A3 (en) | 2025-09-10 |
| EP3986419B1 (en) | 2025-05-14 |
| ES3036963T3 (en) | 2025-09-25 |
| TW202114706A (en) | 2021-04-16 |
| SI3986419T1 (en) | 2025-09-30 |
| WO2020257306A1 (en) | 2020-12-24 |
| HRP20250815T1 (en) | 2025-09-12 |
| EP4599892A2 (en) | 2025-08-13 |
| LT3986419T (en) | 2025-08-25 |
| CN114340639A (en) | 2022-04-12 |
| FI3986419T3 (en) | 2025-07-24 |
| DK3986419T3 (en) | 2025-08-04 |
| PT3986419T (en) | 2025-07-31 |
| US20230144152A1 (en) | 2023-05-11 |
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