PL399176A1 - Method for treatment of obesity and overweight, and diseases gastro-oesophageal reflux - Google Patents
Method for treatment of obesity and overweight, and diseases gastro-oesophageal refluxInfo
- Publication number
- PL399176A1 PL399176A1 PL399176A PL39917612A PL399176A1 PL 399176 A1 PL399176 A1 PL 399176A1 PL 399176 A PL399176 A PL 399176A PL 39917612 A PL39917612 A PL 39917612A PL 399176 A1 PL399176 A1 PL 399176A1
- Authority
- PL
- Poland
- Prior art keywords
- adrc
- cells
- stomach
- overweight
- gastric
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 206010033307 Overweight Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 235000020824 obesity Nutrition 0.000 title abstract 2
- 208000021302 gastroesophageal reflux disease Diseases 0.000 title 1
- 101710163391 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase Proteins 0.000 abstract 3
- 210000002784 stomach Anatomy 0.000 abstract 3
- 230000002496 gastric effect Effects 0.000 abstract 2
- 230000001172 regenerating effect Effects 0.000 abstract 2
- 210000000577 adipose tissue Anatomy 0.000 abstract 1
- 238000007681 bariatric surgery Methods 0.000 abstract 1
- 210000002318 cardia Anatomy 0.000 abstract 1
- 238000013110 gastrectomy Methods 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000004899 motility Effects 0.000 abstract 1
- 230000003387 muscular Effects 0.000 abstract 1
- 230000011514 reflex Effects 0.000 abstract 1
- 230000036186 satiety Effects 0.000 abstract 1
- 235000019627 satiety Nutrition 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Prostheses (AREA)
Abstract
Sposób leczenia otylosci i nadwagi oraz choroby refleksowej zoladkowo-przelykowej (GERD) polega na tym, ze komórki macierzyste i regeneracyjne wyodrebnione z wlasnej tkanki tluszczowej (ADRC - Adipose Derived Regenerative Cells) wstrzykuje sie w tkanke podsluzowa lub miesniowa, zoladka w okolicach wpustu i dna zoladka. Wyodrebnione komórki ADRC podaje sie w procedurach endoskopowych lub chirurgicznych otwartych lub laparoskopowych. Wyodrebnione komórki ADRC wzbogaca sie dodatkiem graftu tluszczowego w ilosci minimum 5 ml i nie wiecej niz 25 ml. Sposób stanowi uzupelnienie innych procedur bariatrycznych ograniczajacych wielkosc zoladka, jak regulowana opaska zoladkowa, czesciowa resekcja rekawowa zoladka lub wypelniajacych zoladek, jak implanty wewnatrzzoladkowe lub wplywajacych na motoryke albo wywolanie uczucia sytosci poprzez elektrostymulacje (neurostymulatory).The method of treating obesity and overweight and gastroesophageal reflex disease (GERD) is that stem and regenerative cells separated from their own adipose tissue (ADRC - Adipose Derived Regenerative Cells) are injected into the submucous or muscular tissue, the stomach around the cardia and fundus stomach. Separated ADRC cells are administered in open or laparoscopic endoscopic or surgical procedures. The isolated ADRC cells are enriched with a minimum of 5 ml fat graft and no more than 25 ml. The method complements other bariatric procedures limiting the size of the stomach, such as an adjustable gastric band, partial gastrectomy or gastric filling, such as intra-gastric implants or affecting motility or inducing satiety through electrostimulation).
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL399176A PL399176A1 (en) | 2012-05-14 | 2012-05-14 | Method for treatment of obesity and overweight, and diseases gastro-oesophageal reflux |
| PCT/PL2013/000063 WO2013172724A1 (en) | 2012-05-14 | 2013-05-14 | Method for treating obesity and overweight and gastro-oesophageal reflux disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL399176A PL399176A1 (en) | 2012-05-14 | 2012-05-14 | Method for treatment of obesity and overweight, and diseases gastro-oesophageal reflux |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL399176A1 true PL399176A1 (en) | 2013-11-25 |
Family
ID=48949200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL399176A PL399176A1 (en) | 2012-05-14 | 2012-05-14 | Method for treatment of obesity and overweight, and diseases gastro-oesophageal reflux |
Country Status (2)
| Country | Link |
|---|---|
| PL (1) | PL399176A1 (en) |
| WO (1) | WO2013172724A1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5393119B2 (en) * | 2008-12-05 | 2014-01-22 | 日本メナード化粧品株式会社 | Method for inducing differentiation of stem cells into brown adipocytes |
| US20100160995A1 (en) | 2008-12-18 | 2010-06-24 | Jerome Dargent | Method for treating obesity |
| KR101967492B1 (en) * | 2011-05-19 | 2019-04-09 | 메소블라스트, 아이엔씨. | Methods for treating obesity and/or metabolic syndrome |
| AU2012275335B2 (en) * | 2011-06-29 | 2017-04-20 | Biorestorative Therapies, Inc. | Brown fat cell compositions and methods |
-
2012
- 2012-05-14 PL PL399176A patent/PL399176A1/en unknown
-
2013
- 2013-05-14 WO PCT/PL2013/000063 patent/WO2013172724A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013172724A1 (en) | 2013-11-21 |
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