PL401493A1 - Kompleksy wanadu z hydrazydohydrazonami, sposób ich otrzymywania, preparaty farmaceutyczne oraz zastosowanie - Google Patents

Kompleksy wanadu z hydrazydohydrazonami, sposób ich otrzymywania, preparaty farmaceutyczne oraz zastosowanie

Info

Publication number
PL401493A1
PL401493A1 PL401493A PL40149312A PL401493A1 PL 401493 A1 PL401493 A1 PL 401493A1 PL 401493 A PL401493 A PL 401493A PL 40149312 A PL40149312 A PL 40149312A PL 401493 A1 PL401493 A1 PL 401493A1
Authority
PL
Poland
Prior art keywords
complexes
vanadium
group
vanadium complexes
hydrazones
Prior art date
Application number
PL401493A
Other languages
English (en)
Other versions
PL231079B1 (pl
Inventor
Ryszard Gryboś
Janusz Szklarzewicz
Dariusz Matoga
Grzegorz Kazek
Marek Stępniewski
Mirosław Krośniak
Grzegorz Nowak
Patrycja Paciorek
Piotr Zabierowski
Original Assignee
Uniwersytet Jagielloński
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Jagielloński filed Critical Uniwersytet Jagielloński
Priority to PL401493A priority Critical patent/PL231079B1/pl
Priority to PCT/PL2013/000114 priority patent/WO2014073992A1/en
Publication of PL401493A1 publication Critical patent/PL401493A1/pl
Publication of PL231079B1 publication Critical patent/PL231079B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/005—Compounds of elements of Group 5 of the Periodic Table without metal-carbon linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Przedmiotem wynalazku są kompleksy wanadu o wzorze ogólnym M[VX(ONO)y(L)n] mS, gdzie X oznacza atom tlenu lub jest nieobecny, L oznacza L1 lub L2, przy czym L1 oznacza anion fluorowca lub obojętną lub zdeprotonowaną cząsteczkę rozpuszczalnika wybranego z grupy zawierającej alkohole C1-C12 i/lub wodę, a L2 oznacza obojętny lub anionowy ligand NN, NO lub OO-donorowy wybrany z grupy zawierającej: polipirydyny, 1,10-fenantrolinę, pirony, chinoliny lub kwasy pirydynokarboksylowe, S oznacza obojętną cząsteczkę rozpuszczalnika wybranego z grupy zawierającej alkohole C1-C4, wodę lub kwas siarkowy, M może być nieobecny, a gdy jest obecny to oznacza jednododatni kation metalu alkalicznego, kation amonowy, kation alkiloamoniowy, a litery O i N oznaczają atom, przez który wiązany jest ligand do wanadu. Wynalazek obejmuje także sposób wytwarzania kompleksów wanadu, preparaty farmaceutyczne zawierające te kompleksy oraz ich zastosowanie.
PL401493A 2012-11-07 2012-11-07 Kompleksy wanadu z hydrazydohydrazonami, preparaty farmaceutyczne oraz zastosowanie kompleksów wanadu z hydrazydohydrazonami PL231079B1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL401493A PL231079B1 (pl) 2012-11-07 2012-11-07 Kompleksy wanadu z hydrazydohydrazonami, preparaty farmaceutyczne oraz zastosowanie kompleksów wanadu z hydrazydohydrazonami
PCT/PL2013/000114 WO2014073992A1 (en) 2012-11-07 2013-09-10 Vanadium complexes with hydrazide-hydrazones, process for their preparation, pharmaceutical formulations and the use of thereof.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL401493A PL231079B1 (pl) 2012-11-07 2012-11-07 Kompleksy wanadu z hydrazydohydrazonami, preparaty farmaceutyczne oraz zastosowanie kompleksów wanadu z hydrazydohydrazonami

Publications (2)

Publication Number Publication Date
PL401493A1 true PL401493A1 (pl) 2014-05-12
PL231079B1 PL231079B1 (pl) 2019-01-31

Family

ID=49486638

Family Applications (1)

Application Number Title Priority Date Filing Date
PL401493A PL231079B1 (pl) 2012-11-07 2012-11-07 Kompleksy wanadu z hydrazydohydrazonami, preparaty farmaceutyczne oraz zastosowanie kompleksów wanadu z hydrazydohydrazonami

Country Status (2)

Country Link
PL (1) PL231079B1 (pl)
WO (1) WO2014073992A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106432354B (zh) * 2016-09-30 2018-08-24 山西大学 一种席夫碱钯配合物及其制备方法和应用
CN106749393A (zh) * 2017-01-09 2017-05-31 山西大学 皮考啉腙酸衍生物双氧钒（v）配合物及其制备方法
CN108623625A (zh) * 2018-07-11 2018-10-09 山东理工大学 具有类胰岛素活性的有机钒配合物及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB328157A (en) 1929-06-17 1930-04-24 Ernest Edward Palmer Improvements in and relating to manifolding books
CA1277599C (en) 1986-10-16 1990-12-11 Barry I. Posner Vanadium - peroxide compositions as insulin mimickers
US5155031A (en) 1990-06-07 1992-10-13 Posner Barry I Use of pervanadate as an inhibitor of phosphotyrosine phosphatase
FR2678622B1 (fr) 1991-07-03 1994-11-18 Adir Nouveaux complexes de vanadium, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
IL99666A (en) 1991-10-07 1996-09-12 Yeda Res & Dev Vanadyl complexes of hydroxamate chelators and pharmaceutical compositions comprising them
US5565491A (en) 1994-01-31 1996-10-15 Bristol-Myers Squibb Company Use of phosphotyrosine phospatase inhibitors for controlling cellular proliferation
NL1006681C2 (nl) 1997-07-29 1999-02-08 Gho St Holding Bv Toepassing van fysiologisch acceptabele vanadiumverbindingen, -zouten en -complexen.
IL121748A0 (en) 1997-09-11 1998-02-22 Yeda Res & Dev Vanadium complexes of hydroxamates and pharmaceutical compositions comprising them
US6432941B1 (en) 1998-01-20 2002-08-13 Parker Hughes Institute Vanadium compounds for treating cancer
GB0328157D0 (en) 2003-12-04 2004-01-07 Imp College Innovations Ltd Compounds
US8008035B2 (en) 2007-01-25 2011-08-30 Roche Diagnostics Operations, Inc. Enhancement of vanadium-containing phosphatase inhibitors
US8242092B2 (en) 2008-02-05 2012-08-14 Brent Townshend Protein tyrosine phosphatase inhibitors

Also Published As

Publication number Publication date
WO2014073992A1 (en) 2014-05-15
PL231079B1 (pl) 2019-01-31

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