PL401600A1 - Trisubstituted isoxazolines and a process for their preparation - Google Patents
Trisubstituted isoxazolines and a process for their preparationInfo
- Publication number
- PL401600A1 PL401600A1 PL401600A PL40160012A PL401600A1 PL 401600 A1 PL401600 A1 PL 401600A1 PL 401600 A PL401600 A PL 401600A PL 40160012 A PL40160012 A PL 40160012A PL 401600 A1 PL401600 A1 PL 401600A1
- Authority
- PL
- Poland
- Prior art keywords
- isoxazolines
- trisubstituted
- preparation
- compounds
- substrates
- Prior art date
Links
- 150000002547 isoxazolines Chemical class 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 125000006017 1-propenyl group Chemical group 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000006352 cycloaddition reaction Methods 0.000 abstract 1
- 238000006317 isomerization reaction Methods 0.000 abstract 1
- 150000002545 isoxazoles Chemical class 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Przedmiotem wynalazku są izoksazoliny trójpodstawione, przedstawione wzorem ogólnym 1 oraz sposób ich otrzymywania, charakteryzujący się tym, że substraty w postaci związków allilowych typu QCH2CH=CH2 jako łatwo dostępne reagenty poddaje się sekwencji następujących po sobie reakcji: izomeryzacji do związków 1-propenylowych, homometatezy związków 1-propenylowych i cykloaddycji dipolarnej tlenków nitryli do produktów homometatezy. Otrzymane takim sposobem trójpodstawione izoksazoliny mogą być wykorzystane w syntezie organicznej jako substraty do otrzymywania innych związków na przykład izoksazoli, aminoalkoholi lub aminokwasów.The subject of the invention are trisubstituted isoxazolines, represented by the general formula 1, and the method of their preparation, characterized in that substrates in the form of allyl compounds of the QCH2CH=CH2 type as readily available reagents are subjected to a sequence of the following reactions: isomerization to 1-propenyl compounds, homometathesis of 1-propenyl and dipolar cycloaddition of nitrile oxides to homometathesis products. The trisubstituted isoxazolines obtained in this way can be used in organic synthesis as substrates for the preparation of other compounds, for example isoxazoles, amino alcohols or amino acids.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL401600A PL224926B1 (en) | 2012-11-13 | 2012-11-13 | Trisubstituted isoxazolines and a process for their preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL401600A PL224926B1 (en) | 2012-11-13 | 2012-11-13 | Trisubstituted isoxazolines and a process for their preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL401600A1 true PL401600A1 (en) | 2014-05-26 |
| PL224926B1 PL224926B1 (en) | 2017-02-28 |
Family
ID=50771798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL401600A PL224926B1 (en) | 2012-11-13 | 2012-11-13 | Trisubstituted isoxazolines and a process for their preparation |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL224926B1 (en) |
-
2012
- 2012-11-13 PL PL401600A patent/PL224926B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL224926B1 (en) | 2017-02-28 |
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