PL405040A1 - Nowe pochodne N-[(fenoksy)etoksy]alkiloaminoalkanoli oraz ich zastosowanie do wytwarzania leków - Google Patents

Nowe pochodne N-[(fenoksy)etoksy]alkiloaminoalkanoli oraz ich zastosowanie do wytwarzania leków

Info

Publication number
PL405040A1
PL405040A1 PL405040A PL40504013A PL405040A1 PL 405040 A1 PL405040 A1 PL 405040A1 PL 405040 A PL405040 A PL 405040A PL 40504013 A PL40504013 A PL 40504013A PL 405040 A1 PL405040 A1 PL 405040A1
Authority
PL
Poland
Prior art keywords
phenoxy
ethoxy
amino
alkanols
alkylamino
Prior art date
Application number
PL405040A
Other languages
English (en)
Other versions
PL225258B1 (pl
Inventor
Anna Maria Waszkielewicz
Agnieszka Gunia
Henryk Marona
Original Assignee
Uniwersytet Jagielloński
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Jagielloński filed Critical Uniwersytet Jagielloński
Priority to PL405040A priority Critical patent/PL225258B1/pl
Priority to PCT/PL2014/050047 priority patent/WO2015020545A2/en
Publication of PL405040A1 publication Critical patent/PL405040A1/pl
Publication of PL225258B1 publication Critical patent/PL225258B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Przedmiotem wynalazku sąnowe pochodne N-[(fe noksy) etoksy]alkiloaminoalkanoli o ogólnym wzorze 1, w którym R1 oznacza (CH3)2, (CH3)3 lub Cl i CH3, a R2 oznacza aminoalkanol wybrany z grupy obejmującej (R,S)-2-aminopropan-1-ol; (R)-2-aminopropan-1-ol; (S)-2-aminopropan-1-ol; (R,S)-2-aminobutanl-ol; (R)-2-aminobutan1-ol; (S)-2-aminobutan1-ol; trans-(D,L)-2-aminocykloheksanol; trans-4-aminocykloheksanol (R,S)-2-amino-1-fenyloetanol; 4-hydroksypiperydynę, a także ich dopuszczone do stosowania w lecznictwie sole i leki prekursorowi. Ujawniono również zastosowanie pochodnych N-[(fenoksy)etoksy]alkiloaminoalkanoli o ogólnym wzorze 1 do wytwarzania leku stosowanego w leczeniu i profilaktyce schorzeń lub symptomów o podłożu neurologicznym, zwłaszcza padaczki i lub bólu.
PL405040A 2013-08-09 2013-08-09 Nowe pochodne N-[(fenoksy)etoksy]alkiloaminoalkanoli oraz ich zastosowanie do wytwarzania leków PL225258B1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL405040A PL225258B1 (pl) 2013-08-09 2013-08-09 Nowe pochodne N-[(fenoksy)etoksy]alkiloaminoalkanoli oraz ich zastosowanie do wytwarzania leków
PCT/PL2014/050047 WO2015020545A2 (en) 2013-08-09 2014-08-07 New derivatives of n-[(phenoxy)ethoxy]alkylaminoalkanols and their use for preparation of drugs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL405040A PL225258B1 (pl) 2013-08-09 2013-08-09 Nowe pochodne N-[(fenoksy)etoksy]alkiloaminoalkanoli oraz ich zastosowanie do wytwarzania leków

Publications (2)

Publication Number Publication Date
PL405040A1 true PL405040A1 (pl) 2015-02-16
PL225258B1 PL225258B1 (pl) 2017-03-31

Family

ID=51541274

Family Applications (1)

Application Number Title Priority Date Filing Date
PL405040A PL225258B1 (pl) 2013-08-09 2013-08-09 Nowe pochodne N-[(fenoksy)etoksy]alkiloaminoalkanoli oraz ich zastosowanie do wytwarzania leków

Country Status (2)

Country Link
PL (1) PL225258B1 (pl)
WO (1) WO2015020545A2 (pl)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071552A (en) 1976-05-19 1978-01-31 Ayerst Mckenna And Harrison Ltd. Aryloxy aminobutanols, their preparation and use thereof
PL126478B1 (en) 1978-12-19 1983-08-31 Inst Maszyn Spozywczych Temperature and humidity control system in particulary for smoking and steaming chambers
PL212489A1 (pl) 1978-12-29 1980-07-01 Zaklady Urzadzen Chem
SI1809273T1 (sl) 2004-09-16 2010-08-31 Janssen Pharmaceutica Nv Uporaba 2-fenil-1,2-etandiol-(di)karbamatov za zdravljenje epileptogeneze
WO2009086303A2 (en) * 2007-12-21 2009-07-09 University Of Rochester Method for altering the lifespan of eukaryotic organisms
PL212489B1 (pl) * 2008-01-22 2012-10-31 Univ Jagiellonski Pochodne fenoksyalkiloaminoalkanoli i ich zastosowania
PL220733B1 (pl) 2012-11-07 2015-12-31 Univ Jagielloński Nowe alkanoloamidowe pochodne kwasu cynamonowego oraz zastosowanie alkanoloamidowych pochodnych kwasu cynamonowego do wytwarzania leków

Also Published As

Publication number Publication date
WO2015020545A2 (en) 2015-02-12
WO2015020545A3 (en) 2015-04-02
PL225258B1 (pl) 2017-03-31

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PL405040A1 (pl) Nowe pochodne N-[(fenoksy)etoksy]alkiloaminoalkanoli oraz ich zastosowanie do wytwarzania leków