PL405774A1 - Sposób wykrywania wysokiego genetycznie uwarunkowanego ryzyka raka prostaty - Google Patents
Sposób wykrywania wysokiego genetycznie uwarunkowanego ryzyka raka prostatyInfo
- Publication number
- PL405774A1 PL405774A1 PL40577413A PL40577413A PL405774A1 PL 405774 A1 PL405774 A1 PL 405774A1 PL 40577413 A PL40577413 A PL 40577413A PL 40577413 A PL40577413 A PL 40577413A PL 405774 A1 PL405774 A1 PL 405774A1
- Authority
- PL
- Poland
- Prior art keywords
- mutation
- gene
- chek2
- detecting
- risk
- Prior art date
Links
- 206010060862 Prostate cancer Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000001143 conditioned effect Effects 0.000 title 1
- 230000035772 mutation Effects 0.000 abstract 6
- 101150064168 CHEK2 gene Proteins 0.000 abstract 4
- 101100220617 Homo sapiens CHEK2 gene Proteins 0.000 abstract 4
- 108700028369 Alleles Proteins 0.000 abstract 1
- 208000034826 Genetic Predisposition to Disease Diseases 0.000 abstract 1
- 101100178941 Homo sapiens HOXB13 gene Proteins 0.000 abstract 1
- 101150016316 NBS1 gene Proteins 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 239000012620 biological material Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 102200145956 rs138213197 Human genes 0.000 abstract 1
- 102210018811 rs188140481 Human genes 0.000 abstract 1
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Wynalazek ujawnia sposoby i produkty znajdujące zastosowanie w diagnozowaniu genetycznej predyspozycji do chorób u ludzi i polega na ocenie czy w materiale biologicznym badanej osoby występuje specyficzna zmiana z panelu siedmiu zmian DNA w tym: 1) mutacja 657del5 genu NBS1; 2) mutacja IVS2+1G>A genu CHEK2; 3) mutacja del5395 genu CHEK2; 4) mutacja 1100delC genu CHEK2; 5) mutacja Il157T genu CHEK2; 6) mutacja G84E genu HOXB13; 7) allel A zmiany rs188140481 w regionie 8q24. Wynalazek dotyczy również nowej metody diagnostycznej wykrywającej wysokie ryzyko raka prostaty u mężczyzn w polskiej populacji.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL405774A PL236138B1 (pl) | 2013-10-26 | 2013-10-26 | Sposób wykrywania genetycznie uwarunkowanej wysokiej predyspozycji do raka prostaty |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL405774A PL236138B1 (pl) | 2013-10-26 | 2013-10-26 | Sposób wykrywania genetycznie uwarunkowanej wysokiej predyspozycji do raka prostaty |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL405774A1 true PL405774A1 (pl) | 2015-04-27 |
| PL236138B1 PL236138B1 (pl) | 2020-12-14 |
Family
ID=52987886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL405774A PL236138B1 (pl) | 2013-10-26 | 2013-10-26 | Sposób wykrywania genetycznie uwarunkowanej wysokiej predyspozycji do raka prostaty |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL236138B1 (pl) |
-
2013
- 2013-10-26 PL PL405774A patent/PL236138B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL236138B1 (pl) | 2020-12-14 |
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