PL406418A1 - Amine derivative of azobenzene and the method of its production - Google Patents

Amine derivative of azobenzene and the method of its production

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Publication number
PL406418A1
PL406418A1 PL406418A PL40641813A PL406418A1 PL 406418 A1 PL406418 A1 PL 406418A1 PL 406418 A PL406418 A PL 406418A PL 40641813 A PL40641813 A PL 40641813A PL 406418 A1 PL406418 A1 PL 406418A1
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PL
Poland
Prior art keywords
azobenzene
aminoethyl
trifluoroacetic acid
added
amino derivative
Prior art date
Application number
PL406418A
Other languages
Polish (pl)
Other versions
PL221867B1 (en
Inventor
Piotr Młynarz
Katarzyna Matczyszyn
Zimowit Pokladek
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL406418A priority Critical patent/PL221867B1/en
Publication of PL406418A1 publication Critical patent/PL406418A1/en
Publication of PL221867B1 publication Critical patent/PL221867B1/en

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Abstract

Przedmiotem wynalazku jest aminowa pochodna azobenzenu w postaci N-[N'-(2'-aminoetylo)-2-aminoetylo]azobenzeno-4- karboksyamidu o wzorze 1 znajdująca zastosowanie jako molekularny przełącznik stosowany w biologii molekularnej, inżynierii materiałowej, chemicznej diagnostyce medycznej oraz jako składnik barwników czy też jako element pamięci optycznych. Sposób wytwarzania aminowej pochodnej azobenzenu w postaci N-[N'-(2'-aminoetylo)-2-aminoetylo]azobenzeno-4- karboksyamidu o wzorze 1 polega na tym, że do N1-Boc-2,2'-iminodietylaminy dodaje się trietyloaminy, przez mieszaninę przepuszcza się azot i całość ochładza się do 0°C, po czym wkrapla się chlorek azobenzeno-4-karbonylowy w obecności bezwodnego dichlorometanu, a następnie otrzymaną N-Boc aminową pochodną azobenzenu umieszcza się w dichlorometanie i dodaje się kwasu trifluorooctowego, otrzymany roztwór miesza się przez 2 godziny, po czym odparowuje się rozpuszczalnik oraz kwas trifluorooctwy pod zmniejszonym ciśnieniem, w wyniku czego otrzymuje się aminową pochodna azobenzenu o wzorze w formie jego soli kwasu trifluorooctowego, w postaci pomarańczowego proszku.The subject of the invention is an amino derivative of azobenzene in the form of N- [N '- (2'-aminoethyl) -2-aminoethyl] azobenzene-4-carboxamide of formula 1, which is used as a molecular switch used in molecular biology, material engineering, chemical medical diagnostics and as a component of dyes or as an element of optical memories. The method for producing the amine derivative of azobenzene in the form of N- [N '- (2'-aminoethyl) -2-aminoethyl] azobenzene-4-carboxamide of formula 1 consists in adding N1-Boc-2,2'-iminodiethylamine triethylamine, nitrogen is bubbled through the mixture and the whole is cooled to 0 ° C, then azobenzene-4-carbonyl chloride is added dropwise in the presence of anhydrous dichloromethane, and then the N-Boc amino derivative of azobenzene is added to dichloromethane and trifluoroacetic acid is added, the resulting solution is stirred for 2 hours, then the solvent and trifluoroacetic acid are evaporated under reduced pressure to give the amino derivative of azobenzene in the form of its trifluoroacetic acid salt as an orange powder.

PL406418A 2013-12-09 2013-12-09 Amine derivative of azobenzene and a method for its preparation PL221867B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL406418A PL221867B1 (en) 2013-12-09 2013-12-09 Amine derivative of azobenzene and a method for its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL406418A PL221867B1 (en) 2013-12-09 2013-12-09 Amine derivative of azobenzene and a method for its preparation

Publications (2)

Publication Number Publication Date
PL406418A1 true PL406418A1 (en) 2014-07-07
PL221867B1 PL221867B1 (en) 2016-06-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL406418A PL221867B1 (en) 2013-12-09 2013-12-09 Amine derivative of azobenzene and a method for its preparation

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PL (1) PL221867B1 (en)

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Publication number Publication date
PL221867B1 (en) 2016-06-30

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