PL408210A1 - Syntetyczna biblioteka białek opartych na sekwencji zmiennych receptorów limfocytów minoga morskiego oraz białko wiążące marker nowotworowy S100A7 - Google Patents
Syntetyczna biblioteka białek opartych na sekwencji zmiennych receptorów limfocytów minoga morskiego oraz białko wiążące marker nowotworowy S100A7Info
- Publication number
- PL408210A1 PL408210A1 PL408210A PL40821014A PL408210A1 PL 408210 A1 PL408210 A1 PL 408210A1 PL 408210 A PL408210 A PL 408210A PL 40821014 A PL40821014 A PL 40821014A PL 408210 A1 PL408210 A1 PL 408210A1
- Authority
- PL
- Poland
- Prior art keywords
- sequence
- protein binding
- lymphocyte receptors
- synthetic library
- proteins based
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 241000251745 Petromyzon marinus Species 0.000 title abstract 2
- 210000004698 lymphocyte Anatomy 0.000 title abstract 2
- 239000003550 marker Substances 0.000 title 1
- 230000001613 neoplastic effect Effects 0.000 title 1
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 239000000439 tumor marker Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
Abstract
Przedmiotem wynalazku jest białko oparte na sekwencji zmiennych receptorów limfocytów minoga morskiego (VLR), o określonej sekwencji oraz białko VLR wiążące marker nowotworowy S100A7 zawierające określone sekwencje jak również zastosowanie białka w diagnostyce, chromatografii powinowactwa oraz immunochemii.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL408210A PL232192B1 (pl) | 2014-05-15 | 2014-05-15 | Syntetyczna biblioteka białek opartych na sekwencji zmiennych receptorów limfocytów minoga morskiego oraz białko wiążące marker nowotworowy S100A7 |
| PCT/PL2015/050016 WO2015174869A1 (en) | 2014-05-15 | 2015-05-15 | Synthetic library of proteins based on sea lamprey's sequence of variable lymphocyte receptors, andcancer marker s100a7 binding protein |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL408210A PL232192B1 (pl) | 2014-05-15 | 2014-05-15 | Syntetyczna biblioteka białek opartych na sekwencji zmiennych receptorów limfocytów minoga morskiego oraz białko wiążące marker nowotworowy S100A7 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL408210A1 true PL408210A1 (pl) | 2015-11-23 |
| PL232192B1 PL232192B1 (pl) | 2019-05-31 |
Family
ID=53476952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL408210A PL232192B1 (pl) | 2014-05-15 | 2014-05-15 | Syntetyczna biblioteka białek opartych na sekwencji zmiennych receptorów limfocytów minoga morskiego oraz białko wiążące marker nowotworowy S100A7 |
Country Status (2)
| Country | Link |
|---|---|
| PL (1) | PL232192B1 (pl) |
| WO (1) | WO2015174869A1 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12077609B2 (en) | 2018-12-21 | 2024-09-03 | Wisconsin Alumni Research Foundation | Variable lymphocyte receptors that target the brain extracellular matrix and methods of use |
| WO2020167735A1 (en) | 2019-02-11 | 2020-08-20 | Wisconsin Alumni Research Foundation | Variable lymphocyte receptors that target the blood brain barrier and methods of use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1773872T3 (en) | 2004-05-21 | 2017-05-08 | Uab Res Found | VARIABLE Lymphocyte Receptors, Associated Polypeptides and Nucleic Acids, and Uses thereof |
| CA2659574C (en) * | 2006-08-02 | 2017-04-25 | The Uab Research Foundation | Methods and compositions related to soluble monoclonal variable lymphocyte receptors of defined antigen specificity |
| US9127087B2 (en) | 2008-12-01 | 2015-09-08 | University Of Maryland, Baltimore | High affinity recombinant sea lamprey antibodies selected by a Yeast Surface Display platform |
-
2014
- 2014-05-15 PL PL408210A patent/PL232192B1/pl unknown
-
2015
- 2015-05-15 WO PCT/PL2015/050016 patent/WO2015174869A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| PL232192B1 (pl) | 2019-05-31 |
| WO2015174869A1 (en) | 2015-11-19 |
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