PL409664A1 - Application of the lysine phosphonic analogues and arginine for inhibiting activity of proteolytic protease NS2B/NS3 of West Nole virus - Google Patents

Application of the lysine phosphonic analogues and arginine for inhibiting activity of proteolytic protease NS2B/NS3 of West Nole virus

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Publication number
PL409664A1
PL409664A1 PL409664A PL40966414A PL409664A1 PL 409664 A1 PL409664 A1 PL 409664A1 PL 409664 A PL409664 A PL 409664A PL 40966414 A PL40966414 A PL 40966414A PL 409664 A1 PL409664 A1 PL 409664A1
Authority
PL
Poland
Prior art keywords
arginine
lysine
west
virus
nole
Prior art date
Application number
PL409664A
Other languages
Polish (pl)
Other versions
PL229436B1 (en
Inventor
Marcin Skoreński
Józef Oleksyszyn
Marcin Sieńczyk
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL409664A priority Critical patent/PL229436B1/en
Publication of PL409664A1 publication Critical patent/PL409664A1/en
Publication of PL229436B1 publication Critical patent/PL229436B1/en

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Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Wynalazek dotyczy zastosowania fosfonowych analogów lizyny oraz argininy o wzorze ogólnym A, w którym R oznacza podstawnik (4-amino)butanowy, (3-guanidyno)propanowy, (4-amino)benzylowy, (4-guanidyno)benzylowy, (4-guanidyno)fenylowy, (4-amido)fenylowy jako inhibitorów proteazy ekspresjonowanej przez wirusa Zachodniego Nilu (WNV).The invention relates to the use of phosphono analogues of lysine and arginine of the general formula A, wherein R is a (4-amino)butano, (3-guanidino)propano, (4-amino)benzyl, (4-guanidino)benzyl, (4-guanidino)phenyl, (4-amido)phenyl substituent as inhibitors of the protease expressed by West Nile virus (WNV).

PL409664A 2014-10-02 2014-10-02 Application of the lysine phosphonic analogues and arginine for inhibiting activity of proteolytic protease NS2B/NS3 of West Nole virus PL229436B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL409664A PL229436B1 (en) 2014-10-02 2014-10-02 Application of the lysine phosphonic analogues and arginine for inhibiting activity of proteolytic protease NS2B/NS3 of West Nole virus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL409664A PL229436B1 (en) 2014-10-02 2014-10-02 Application of the lysine phosphonic analogues and arginine for inhibiting activity of proteolytic protease NS2B/NS3 of West Nole virus

Publications (2)

Publication Number Publication Date
PL409664A1 true PL409664A1 (en) 2015-06-08
PL229436B1 PL229436B1 (en) 2018-07-31

Family

ID=53269208

Family Applications (1)

Application Number Title Priority Date Filing Date
PL409664A PL229436B1 (en) 2014-10-02 2014-10-02 Application of the lysine phosphonic analogues and arginine for inhibiting activity of proteolytic protease NS2B/NS3 of West Nole virus

Country Status (1)

Country Link
PL (1) PL229436B1 (en)

Also Published As

Publication number Publication date
PL229436B1 (en) 2018-07-31

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