PL410454A1 - Sposób identyfikowania odpowiedzi chorego na łuszczycę na leczenie genisteiną molekularny test oraz zastosowanie ekspresji genów do wykrywania in vitro łuszczycy - Google Patents

Sposób identyfikowania odpowiedzi chorego na łuszczycę na leczenie genisteiną molekularny test oraz zastosowanie ekspresji genów do wykrywania in vitro łuszczycy

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Publication number
PL410454A1
PL410454A1 PL410454A PL41045414A PL410454A1 PL 410454 A1 PL410454 A1 PL 410454A1 PL 410454 A PL410454 A PL 410454A PL 41045414 A PL41045414 A PL 41045414A PL 410454 A1 PL410454 A1 PL 410454A1
Authority
PL
Poland
Prior art keywords
psoriasis
patient
response
genistein
treatment
Prior art date
Application number
PL410454A
Other languages
English (en)
Inventor
Grzegorz Węgrzyn
Magdalena Gabig-Cimińska
Joanna Jakóbkiewicz-Banecka
Marta Moskot
Elwira Smolińska
Original Assignee
Uniwersytet Gdański
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Gdański filed Critical Uniwersytet Gdański
Priority to PL410454A priority Critical patent/PL410454A1/pl
Priority to EP15828396.0A priority patent/EP3230470A1/en
Priority to PCT/PL2015/000198 priority patent/WO2016093718A1/en
Publication of PL410454A1 publication Critical patent/PL410454A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Przedmiotem wynalazku jest sposób identyfikowania molekularnej odpowiedzi pacjenta chorego na łuszczycę na leczenie genisteiną, gdzie określa się w próbce biologicznej pobranej od pacjenta poziom ekspresji 30 genów przedstawionych poniżej: EZH2, CDC42EP5, F12, GJB2, KRT6B, MALL, PI3, SFT2D2, SRM, SYNCRIP, THBD, ACACB, CAT, FADS1, FASN, FOXC1, FOXO1, JUN, MEGF9, MYH10, PCYOX1 RHOB, RHOBTB3, SSPN, TIMP3, TUFT1, UST, ZNF12, ZNF483, ZNF652. Ujawniono także molekularny test do wykrywania odpowiedzi pacjenta chorego na łuszczycę na leczenie genisteiną oraz zastosowanie ekspresji 30 genów do wykrywania in vitro łuszczycy u pacjenta.
PL410454A 2014-12-08 2014-12-08 Sposób identyfikowania odpowiedzi chorego na łuszczycę na leczenie genisteiną molekularny test oraz zastosowanie ekspresji genów do wykrywania in vitro łuszczycy PL410454A1 (pl)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PL410454A PL410454A1 (pl) 2014-12-08 2014-12-08 Sposób identyfikowania odpowiedzi chorego na łuszczycę na leczenie genisteiną molekularny test oraz zastosowanie ekspresji genów do wykrywania in vitro łuszczycy
EP15828396.0A EP3230470A1 (en) 2014-12-08 2015-12-08 Methods for identifying response of patients suffering from psoriasis to genistein treatment and molecular assays therefor
PCT/PL2015/000198 WO2016093718A1 (en) 2014-12-08 2015-12-08 Methods for identifying response of patients suffering from psoriasis to genistein treatment and molecular assays therefor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL410454A PL410454A1 (pl) 2014-12-08 2014-12-08 Sposób identyfikowania odpowiedzi chorego na łuszczycę na leczenie genisteiną molekularny test oraz zastosowanie ekspresji genów do wykrywania in vitro łuszczycy

Publications (1)

Publication Number Publication Date
PL410454A1 true PL410454A1 (pl) 2016-06-20

Family

ID=55221478

Family Applications (1)

Application Number Title Priority Date Filing Date
PL410454A PL410454A1 (pl) 2014-12-08 2014-12-08 Sposób identyfikowania odpowiedzi chorego na łuszczycę na leczenie genisteiną molekularny test oraz zastosowanie ekspresji genów do wykrywania in vitro łuszczycy

Country Status (3)

Country Link
EP (1) EP3230470A1 (pl)
PL (1) PL410454A1 (pl)
WO (1) WO2016093718A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101933694B1 (ko) 2017-06-30 2018-12-28 동국대학교 산학협력단 제니스테인 노출 진단용 바이오 마커를 포함하는 진단키트
CN110004220A (zh) * 2019-01-11 2019-07-12 北京蛋白质组研究中心 一种银屑病血清标志物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005520479A (ja) * 2000-05-09 2005-07-14 ジェネティクス インスティテュート，エルエルシー 乾癬の確認、評価、予防および治療のための組成物、キットおよび方法
US20090270480A1 (en) * 2005-12-28 2009-10-29 Bernard Amegadzie Markers and Methods for Assessing and Treating Psoriasis and Related Disorders
EP2212442A1 (en) * 2007-10-26 2010-08-04 Galderma Research & Development Non-invasive method to perform skin inflammatory disease pharmaco-genomic studies and diagnosis method thereof

Also Published As

Publication number Publication date
EP3230470A1 (en) 2017-10-18
WO2016093718A1 (en) 2016-06-16

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