PL4119153T3 - Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej - Google Patents

Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Info

Publication number
PL4119153T3
PL4119153T3 PL22185801.2T PL22185801T PL4119153T3 PL 4119153 T3 PL4119153 T3 PL 4119153T3 PL 22185801 T PL22185801 T PL 22185801T PL 4119153 T3 PL4119153 T3 PL 4119153T3
Authority
PL
Poland
Prior art keywords
treatment
infectious disease
targeted therapies
therapies
targeted
Prior art date
Application number
PL22185801.2T
Other languages
English (en)
Inventor
Kipp WEISKOPF
Kim J. HASENKRUG
Cheryl A. Stoddart
Joseph M. Mccune
Irving L. Weissman
Original Assignee
The Board Of Trustees Of The Leland Stanford Junior University
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The Leland Stanford Junior University, The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The Regents Of The University Of California filed Critical The Board Of Trustees Of The Leland Stanford Junior University
Publication of PL4119153T3 publication Critical patent/PL4119153T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Radiation-Therapy Devices (AREA)
PL22185801.2T 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej PL4119153T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361761133P 2013-02-05 2013-02-05

Publications (1)

Publication Number Publication Date
PL4119153T3 true PL4119153T3 (pl) 2024-09-02

Family

ID=51300110

Family Applications (2)

Application Number Title Priority Date Filing Date
PL22185801.2T PL4119153T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej
PL20163565.3T PL3721888T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL20163565.3T PL3721888T3 (pl) 2013-02-05 2014-02-05 Terapie ukierunkowane na cd47 w leczeniu choroby zakaźnej

Country Status (10)

Country Link
US (6) US9771428B2 (pl)
EP (4) EP2953633B1 (pl)
CA (1) CA2900256C (pl)
DK (1) DK3311824T3 (pl)
ES (4) ES2649165T3 (pl)
HR (1) HRP20200565T1 (pl)
PL (2) PL4119153T3 (pl)
PT (1) PT3721888T (pl)
SI (1) SI3721888T1 (pl)
WO (1) WO2014124028A1 (pl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2953633B1 (en) * 2013-02-05 2017-10-04 The Board of Trustees of the Leland Stanford Junior University Cd47 targeted therapies for the treatment of infectious disease
EP3046627B1 (en) 2013-09-18 2019-10-23 The Board of Trustees of the Leland Stanford Junior University Modulation of efferocytosis pathways for treatment of atherosclerotic disease
WO2016138306A1 (en) 2015-02-27 2016-09-01 The Board Of Trustees Of The Leland Stanford Junior University Combination therapy for treatment of coronary artery disease
CN114425077A (zh) * 2015-05-18 2022-05-03 起源生物医药公司 Sirp多肽组合物和使用方法
AU2016304794B2 (en) 2015-08-07 2021-07-15 ALX Oncology Inc. Constructs having a SIRP-alpha domain or variant thereof
US12344669B2 (en) 2016-06-17 2025-07-01 Changchun Genescience Pharmaceutical Co., Ltd. Anti-CD47 monoclonal antibody and use thereof
CN106084052B (zh) * 2016-06-17 2019-12-27 长春金赛药业股份有限公司 抗cd47单克隆抗体及其应用
JOP20190009A1 (ar) 2016-09-21 2019-01-27 Alx Oncology Inc أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
EP3532497B1 (en) 2016-10-26 2024-07-24 The Board of Trustees of the Leland Stanford Junior University Modified immunoglobulin hinge regions to reduce hemagglutination
AU2017371070B2 (en) 2016-12-09 2025-01-02 Alector Llc Anti-SIRP-alpha antibodies and methods of use thereof
CN110248645B (zh) 2016-12-29 2022-04-26 韩国科学技术研究院 基于外来体的抗癌剂
EP3747438A1 (en) * 2017-07-24 2020-12-09 Stichting Het Nederlands Kanker Instituut- Antoni van Leeuwenhoek Ziekenhuis Treating pathological conditions by direct and indirect targeting of sirpa - cd47 interaction
BR112020001653A2 (pt) 2017-07-26 2020-07-21 Forty Seven, Inc. anticorpos anti-sirp-alfa e métodos relacionados
JP7262440B2 (ja) 2017-08-02 2023-04-21 フェインズ セラピューティクス，インコーポレーテッド 抗ｃｄ４７抗体及びその使用
SG11202004864TA (en) 2017-12-01 2020-06-29 Seattle Genetics Inc Cd47 antibodies and uses thereof for treating cancer
PE20201265A1 (es) 2018-03-21 2020-11-19 Alx Oncology Inc Anticuerpos contra proteina alfa reguladora de senal y metodos de uso
GB201807945D0 (en) 2018-05-16 2018-06-27 Ospedale San Raffaele Srl Vector production
JP7337099B2 (ja) 2018-05-25 2023-09-01 アレクトル エルエルシー 抗ｓｉｒｐａ抗体およびその使用法
BR112021005585A2 (pt) 2018-09-27 2021-06-29 Celgene Corporation proteínas de ligação a sirpa e métodos de uso das mesmas
US11591390B2 (en) 2018-09-27 2023-02-28 Celgene Corporation SIRP-α binding proteins and methods of use thereof
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
GB2593632B (en) * 2018-10-29 2023-05-24 Umc Utrecht Holding Bv IGA mediated killing of aberrant cells by CD47-Sirpalpha checkpoint inhibition of neutrophils
CN114126648A (zh) 2019-05-31 2022-03-01 Alx肿瘤生物技术公司 用SIRPα Fc融合体组合免疫检查点抑制剂治疗癌症的方法
EP3756688A1 (en) 2019-06-25 2020-12-30 Université de Nantes Inhibitor of surface protein (sp-d) / sirpa / shp2 pathway for use in the prevention and/or treatment of secondary infection
CN121243368A (zh) 2019-11-27 2026-01-02 Alx肿瘤生物技术公司 用于治疗癌症的组合疗法
JP2024520902A (ja) 2021-05-13 2024-05-27 エーエルエックス オンコロジー インコーポレイテッド がんを治療するための併用療法
KR102690136B1 (ko) * 2021-06-30 2024-07-31 연세대학교 산학협력단 바이러스 및 박테리아의 중복 감염 치료용 조성물
WO2025264856A1 (en) * 2024-06-19 2025-12-26 Whitehead Institute For Biomedical Research Antibody combinations for macrophage stimulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995010265A1 (en) 1993-10-15 1995-04-20 Cytrx Corporation Therapeutic delivery compositions and methods of use thereof
US8377448B2 (en) 2006-05-15 2013-02-19 The Board Of Trustees Of The Leland Standford Junior University CD47 related compositions and methods for treating immunological diseases and disorders
EP2111869A1 (en) * 2008-04-23 2009-10-28 Stichting Sanquin Bloedvoorziening Compositions and methods to enhance the immune system
HRP20150553T1 (hr) * 2009-05-15 2015-08-28 University Health Network Sastavi i metode za lijeäśenje hematoloških maligniteta ciljajuä†i sirp - cd47 interakciju
PT2569013T (pt) 2010-05-14 2017-02-08 Univ Leland Stanford Junior Anticorpos monoclonais humanizados e quiméricos para cd47
EP2953633B1 (en) * 2013-02-05 2017-10-04 The Board of Trustees of the Leland Stanford Junior University Cd47 targeted therapies for the treatment of infectious disease

Also Published As

Publication number Publication date
PT3721888T (pt) 2022-11-02
WO2014124028A1 (en) 2014-08-14
US10723803B2 (en) 2020-07-28
EP4119153B1 (en) 2024-04-24
US9771428B2 (en) 2017-09-26
US20150376288A1 (en) 2015-12-31
EP4119153C0 (en) 2024-04-24
EP3311824A1 (en) 2018-04-25
EP3721888B1 (en) 2022-07-20
US20220098322A1 (en) 2022-03-31
CA2900256C (en) 2023-03-21
EP3721888A1 (en) 2020-10-14
EP3311824B1 (en) 2020-03-25
ES2983571T3 (es) 2024-10-23
ES2649165T3 (es) 2018-01-10
US11780931B2 (en) 2023-10-10
US20170362332A1 (en) 2017-12-21
EP2953633B1 (en) 2017-10-04
HRP20200565T1 (hr) 2020-08-07
US12410259B2 (en) 2025-09-09
EP2953633A4 (en) 2016-09-14
US20190092873A1 (en) 2019-03-28
US11230607B2 (en) 2022-01-25
EP4119153A1 (en) 2023-01-18
DK3311824T3 (da) 2020-04-14
PL3721888T3 (pl) 2023-04-11
ES2928001T3 (es) 2022-11-14
US20230406952A1 (en) 2023-12-21
US20200354469A1 (en) 2020-11-12
US10184004B2 (en) 2019-01-22
SI3721888T1 (sl) 2023-04-28
CA2900256A1 (en) 2014-08-14
ES2794700T3 (es) 2020-11-18
EP2953633A1 (en) 2015-12-16

Similar Documents

Publication Publication Date Title
EP4119153C0 (en) CD47-TARGETED THERAPIES FOR THE TREATMENT OF INFECTIOUS DISEASES
IL243976B (en) kdm1a inhibitors for disease treatment
PL2943493T3 (pl) Związki terapeutyczne do leczenia zakażeń wirusowych
IL240765A0 (en) Macrocyclic daza-furanones for the treatment of viral infections
AU356625S (en) Rollator
EP2958507A4 (en) MEDICAL MANIPULATOR
HUE057005T2 (hu) Oszlopon történõ vírusinaktiváló eljárások
PL2764881T3 (pl) System leczenia medycznego
EP2982328A4 (en) MEDICAL MANIPULATOR
LT2914254T (lt) Kombinacinės terapijos chemoresistencinių vėžių gydymui
IL234606B (en) Novel methods and composition for treatment of disease
GB201304872D0 (en) Treatment
GB201308440D0 (en) Therapeutic
HUE050413T2 (hu) Kompozíciók és eljárások fertõzéses megbetegedés kezelésére
GB201403716D0 (en) Catalytic treatment
DK2976101T3 (da) Behandlingsfremgangsmåde
GB201313356D0 (en) Therapeutic Intervention
GB201318668D0 (en) Sonosensitive therapeutic
EP2982329A4 (en) MEDICAL MANIPULATOR
EP2953522A4 (en) MEDICAL MANIPULATOR
GB201303737D0 (en) Catalytic treatment
EP2982319A4 (en) MEDICAL MANIPULATOR
EP2982310A4 (en) Medical manipulator
GB201307310D0 (en) Treatment
GB201215184D0 (en) Therapeutic virus