PL413090A1 - Startery, sposób mikrobiologicznej analizy materiału biologicznego, zastosowanie metody sekwencjonowania NGS w diagnostyce mikrobiologicznej i zestaw diagnostyczny - Google Patents

Startery, sposób mikrobiologicznej analizy materiału biologicznego, zastosowanie metody sekwencjonowania NGS w diagnostyce mikrobiologicznej i zestaw diagnostyczny

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Publication number
PL413090A1
PL413090A1 PL413090A PL41309015A PL413090A1 PL 413090 A1 PL413090 A1 PL 413090A1 PL 413090 A PL413090 A PL 413090A PL 41309015 A PL41309015 A PL 41309015A PL 413090 A1 PL413090 A1 PL 413090A1
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Poland
Prior art keywords
microbiological
starters
biomaterial
diagnostics
application
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Application number
PL413090A
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English (en)
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PL235777B1 (pl
Inventor
Tomasz Gosiewski
Dominika Salamon
Małgorzata Bulanda
Piotr Radkowski
Agnieszka Ludwig-Gałęzowska
Paweł Wołkow
Agnieszka Sroka
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Uniwersytet Jagielloński
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Priority to PL413090A priority Critical patent/PL235777B1/pl
Priority to PCT/IB2015/056715 priority patent/WO2017009693A1/en
Priority to ES15779009T priority patent/ES2850073T3/es
Priority to US15/740,050 priority patent/US20180195111A1/en
Priority to EP15779009.8A priority patent/EP3320110B1/en
Publication of PL413090A1 publication Critical patent/PL413090A1/pl
Publication of PL235777B1 publication Critical patent/PL235777B1/pl

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2549/00—Reactions characterised by the features used to influence the efficiency or specificity
    • C12Q2549/10—Reactions characterised by the features used to influence the efficiency or specificity the purpose being that of reducing false positive or false negative signals
    • C12Q2549/119—Reactions characterised by the features used to influence the efficiency or specificity the purpose being that of reducing false positive or false negative signals using nested primers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00—Nucleic acid detection characterised by assay method
    • C12Q2561/113—Real time assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Przedmiotem wynalazku są: para starterów, sposób mikrobiologicznej analizy materiału biologicznego, zastosowanie metody sekwencjonowania NGS w diagnostyce mikrobiologicznej krwi oraz zestaw diagnostyczny. Opracowana została nowatorska metoda diagnozowania płynów ustrojowych pod kątem mikrobiologicznym tj. kompleksowe badanie profili bakterii w próbkach.
PL413090A 2015-07-10 2015-07-10 Startery, sposób i zestaw diagnostyczny do diagnozowania sepsy PL235777B1 (pl)

Priority Applications (5)

Application Number Priority Date Filing Date Title
PL413090A PL235777B1 (pl) 2015-07-10 2015-07-10 Startery, sposób i zestaw diagnostyczny do diagnozowania sepsy
PCT/IB2015/056715 WO2017009693A1 (en) 2015-07-10 2015-09-03 16s ribosomal rna universal primers and use thereof in microbiological analysis and diagnostics
ES15779009T ES2850073T3 (es) 2015-07-10 2015-09-03 Cebadores universales de ARN ribosómico 16S y su uso en análisis y diagnóstico microbiológico
US15/740,050 US20180195111A1 (en) 2015-07-10 2015-09-03 16s ribosomal rna universal primers and use thereof in microbiological analysis and diagnostics
EP15779009.8A EP3320110B1 (en) 2015-07-10 2015-09-03 16s ribosomal rna universal primers and use thereof in microbiological analysis and diagnostics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL413090A PL235777B1 (pl) 2015-07-10 2015-07-10 Startery, sposób i zestaw diagnostyczny do diagnozowania sepsy

Publications (2)

Publication Number Publication Date
PL413090A1 true PL413090A1 (pl) 2017-01-16
PL235777B1 PL235777B1 (pl) 2020-10-19

Family

ID=54293278

Family Applications (1)

Application Number Title Priority Date Filing Date
PL413090A PL235777B1 (pl) 2015-07-10 2015-07-10 Startery, sposób i zestaw diagnostyczny do diagnozowania sepsy

Country Status (5)

Country Link
US (1) US20180195111A1 (pl)
EP (1) EP3320110B1 (pl)
ES (1) ES2850073T3 (pl)
PL (1) PL235777B1 (pl)
WO (1) WO2017009693A1 (pl)

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KR101833348B1 (ko) * 2016-12-26 2018-03-02 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 유방암 진단방법
KR101942197B1 (ko) * 2016-12-28 2019-01-24 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 전립선질환 진단 방법
KR101944664B1 (ko) * 2017-02-24 2019-02-01 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 파킨슨병 진단방법
KR101940446B1 (ko) * 2017-02-24 2019-01-18 주식회사 엠디헬스케어 미생물 메타게놈 분석을 통한 난소암 진단방법
KR101944665B1 (ko) * 2017-02-24 2019-02-01 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 만성폐쇄성기도질환 진단 방법
KR102008451B1 (ko) * 2017-05-26 2019-08-07 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 자폐증 진단방법
WO2018225945A1 (ko) * 2017-06-07 2018-12-13 주식회사 엠디헬스케어 미생물 메타게놈 분석을 통한 아토피피부염 진단방법
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KR102007783B1 (ko) 2017-10-18 2019-08-07 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 림프종 진단방법
WO2019078434A1 (ko) * 2017-10-18 2019-04-25 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 두경부암 진단방법
WO2019078433A1 (ko) * 2017-10-18 2019-04-25 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 대사증후군 진단방법
WO2019139279A1 (ko) * 2018-01-12 2019-07-18 주식회사 엠디헬스케어 모르가넬라 속 세균 유래 나노소포 및 이의 용도
KR102095355B1 (ko) 2018-01-12 2020-03-31 주식회사 엠디헬스케어 모르가넬라 속 세균 유래 나노소포 및 이의 용도
KR101940950B1 (ko) * 2018-01-23 2019-01-21 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 담관암 진단방법
KR101944660B1 (ko) * 2018-01-29 2019-01-31 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 우울증 진단방법
KR102063196B1 (ko) * 2018-02-06 2020-01-07 주식회사 엠디헬스케어 세균 메타게놈 분석을 통한 과민성장증후군 진단방법
KR102087105B1 (ko) * 2018-02-21 2020-03-10 주식회사 엠디헬스케어 큐프리아비더스 속 세균 유래 나노소포 및 이의 용도
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Also Published As

Publication number Publication date
WO2017009693A1 (en) 2017-01-19
US20180195111A1 (en) 2018-07-12
ES2850073T3 (es) 2021-08-25
EP3320110A1 (en) 2018-05-16
PL235777B1 (pl) 2020-10-19
EP3320110B1 (en) 2020-12-30

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