PL414532A1 - N, N-bis [(hydroxyphosphinyl) methyl]-2-amin alkannoic acids and method for producing them - Google Patents
N, N-bis [(hydroxyphosphinyl) methyl]-2-amin alkannoic acids and method for producing themInfo
- Publication number
- PL414532A1 PL414532A1 PL414532A PL41453215A PL414532A1 PL 414532 A1 PL414532 A1 PL 414532A1 PL 414532 A PL414532 A PL 414532A PL 41453215 A PL41453215 A PL 41453215A PL 414532 A1 PL414532 A1 PL 414532A1
- Authority
- PL
- Poland
- Prior art keywords
- aminoalkanoic
- bis
- methyl
- acids
- molar part
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 8
- 150000007513 acids Chemical class 0.000 title abstract 5
- -1 hydroxyphosphinyl Chemical group 0.000 title abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 6
- BGJSXRVXTHVRSN-UHFFFAOYSA-N 1,3,5-trioxane Chemical compound C1OCOCO1 BGJSXRVXTHVRSN-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- YOTZYFSGUCFUKA-UHFFFAOYSA-N dimethylphosphine Chemical group CPC YOTZYFSGUCFUKA-UHFFFAOYSA-N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- ACVYVLVWPXVTIT-UHFFFAOYSA-N phosphinic acid Chemical compound O[PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-N 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Abstract
Wynalazek dotyczy kwasów N,N-bis[(hydroksyfosfinylo)metylo]-2-aminoalkanowych o wzorze ogólnym 1, w którym R oznacza wodór, metyl, etyl, propyl, izopropyl, butyl, izobutyl, sec-butyl i benzyl, które są przeznaczone do stosowania jako substraty do syntezy kwasów N,N-bis(fosfonometylo)-2-aminoalkanowych oraz poliamfolitów zawierających grupy dimetylofosfinowe i reszty kwasów 2-aminoalkanowych. Zgłoszenie dotyczy również sposobów wytwarzania kwasów N,N-bis[(hydroksyfosfinylo)metylo]-2-aminoalkanowych, które polegają na tym, że jedną część molową kwasu 2-aminoalkanowego poddaje się reakcji z co najmniej jedną częścią molową formaldehydu zawartego w substancji wybranej z grupy formalina, trioksan i paraform, na każdą część molową grup -NH- w kwasie 2-aminoalkanowym, a następnie z co najmniej jedną częścią molową kwasu fosfinowego na każdą część molową grup -NH-w kwasie 2-aminoalkanowym, a reakcję prowadzi się w możliwie najniższej akceptowalnej technologicznie temperaturze, korzystnie w temperaturze 273 - 298 K, w wodzie, aż do przereagowania substratów.The invention relates to N, N-bis [(hydroxyphosphinyl) methyl] -2-aminoalkanoic acids of general formula 1, wherein R is hydrogen, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, sec-butyl and benzyl. for use as substrates for the synthesis of N, N-bis (phosphonomethyl) -2-aminoalkanoic acids and polyampholytes containing dimethylphosphine groups and residues of 2-aminoalkanoic acids. The application also relates to processes for the preparation of N, N-bis [(hydroxyphosphinyl) methyl] -2-aminoalkanoic acids, which consist in the fact that one molar part of 2-aminoalkanoic acid is reacted with at least one molar part of formaldehyde contained in a substance selected from formalin, trioxane and paraform groups, for each molar part of -NH- groups in 2-aminoalkanoic acid, and then with at least one molar part of phosphinic acid for each molar part of -NH-groups in 2-aminoalkanoic acid, and the reaction is carried out in the lowest technologically acceptable temperature, preferably at a temperature of 273 - 298 K, in water until the reactants react.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL414532A PL229268B1 (en) | 2015-10-28 | 2015-10-28 | N, N-bis [(hydroxyphosphinyl) methyl]-2-amin alkannoic acids and method for producing them |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL414532A PL229268B1 (en) | 2015-10-28 | 2015-10-28 | N, N-bis [(hydroxyphosphinyl) methyl]-2-amin alkannoic acids and method for producing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL414532A1 true PL414532A1 (en) | 2016-07-18 |
| PL229268B1 PL229268B1 (en) | 2018-06-29 |
Family
ID=56370130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL414532A PL229268B1 (en) | 2015-10-28 | 2015-10-28 | N, N-bis [(hydroxyphosphinyl) methyl]-2-amin alkannoic acids and method for producing them |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL229268B1 (en) |
-
2015
- 2015-10-28 PL PL414532A patent/PL229268B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL229268B1 (en) | 2018-06-29 |
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