PL417384A1 - Graft of Gram-positive Bacillus subtillis, immunogenic composition, oral vaccine and its application against the influenza type A virus - Google Patents

Graft of Gram-positive Bacillus subtillis, immunogenic composition, oral vaccine and its application against the influenza type A virus

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Publication number
PL417384A1
PL417384A1 PL417384A PL41738416A PL417384A1 PL 417384 A1 PL417384 A1 PL 417384A1 PL 417384 A PL417384 A PL 417384A PL 41738416 A PL41738416 A PL 41738416A PL 417384 A1 PL417384 A1 PL 417384A1
Authority
PL
Poland
Prior art keywords
gram
bacillus subtillis
virus
immunogenic composition
oral vaccine
Prior art date
Application number
PL417384A
Other languages
Polish (pl)
Inventor
Dawid Nidzworski
Tomasz Łęga
Paulina Weiher
Original Assignee
Uniwersytet Gdański
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Gdański filed Critical Uniwersytet Gdański
Priority to PL417384A priority Critical patent/PL417384A1/en
Priority to PCT/PL2016/000060 priority patent/WO2016200281A1/en
Priority to EP16736928.9A priority patent/EP3302545A1/en
Publication of PL417384A1 publication Critical patent/PL417384A1/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Przedmiotem zgłoszenia jest szczep gram - dodatniej laseczki Bacillus subtillis, który wytwarza rekombinowane przetrwalniki, prezentujące na powierzchni antygen M1 w fuzji z białkiem CotZ płaszcza przetrwalników Bacillus subtillis. Zgłoszenie obejmuje też kompozycję immunogenną do indukowania w organizmie człowieka odpowiedzi immunologicznej przeciwko wirusowi grypy A, gdzie szczep gram - dodatni laseczki Bacillus subtillis wytwarza rekombinowane przetrwalniki. Ponadto zgłoszenie zawiera również zastosowanie szczepu gram - dodatniej laseczki Bacillus subtillis do wytwarzania doustnej szczepionki, stosowanej do immunizacji przeciwko wirusowi grypy typu A.The subject of the application is the Gram-positive Bacillus subtillis rod strain, which produces recombinant spores displaying the M1 antigen fused to the CotZ protein of the Bacillus subtillis spore coat. The application also includes an immunogenic composition for inducing an immune response against influenza A virus in the human body, where the Bacillus subtillis gram positive rods produce recombinant spores. In addition, the application also contains the use of the Gram-positive Bacillus subtillis rod for the production of an oral vaccine used for immunization against influenza A virus.

PL417384A 2015-06-08 2016-06-01 Graft of Gram-positive Bacillus subtillis, immunogenic composition, oral vaccine and its application against the influenza type A virus PL417384A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PL417384A PL417384A1 (en) 2016-06-01 2016-06-01 Graft of Gram-positive Bacillus subtillis, immunogenic composition, oral vaccine and its application against the influenza type A virus
PCT/PL2016/000060 WO2016200281A1 (en) 2015-06-08 2016-06-07 The strain of gram-positive bacillus subtilis, recombinant spores, immunogenic composition, an oral vaccine, and its use against influenza virus type a
EP16736928.9A EP3302545A1 (en) 2015-06-08 2016-06-07 The strain of gram-positivebacillus subtilis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL417384A PL417384A1 (en) 2016-06-01 2016-06-01 Graft of Gram-positive Bacillus subtillis, immunogenic composition, oral vaccine and its application against the influenza type A virus

Publications (1)

Publication Number Publication Date
PL417384A1 true PL417384A1 (en) 2017-12-04

Family

ID=60473124

Family Applications (1)

Application Number Title Priority Date Filing Date
PL417384A PL417384A1 (en) 2015-06-08 2016-06-01 Graft of Gram-positive Bacillus subtillis, immunogenic composition, oral vaccine and its application against the influenza type A virus

Country Status (1)

Country Link
PL (1) PL417384A1 (en)

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