PL417694A1 - α-aminophosphonic acids originating from acetylpyridine and method for producing it - Google Patents

α-aminophosphonic acids originating from acetylpyridine and method for producing it

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Publication number
PL417694A1
PL417694A1 PL417694A PL41769416A PL417694A1 PL 417694 A1 PL417694 A1 PL 417694A1 PL 417694 A PL417694 A PL 417694A PL 41769416 A PL41769416 A PL 41769416A PL 417694 A1 PL417694 A1 PL 417694A1
Authority
PL
Poland
Prior art keywords
acetylpyridine
aminophosphonic acids
producing
bromotrimethylsilane
reacted
Prior art date
Application number
PL417694A
Other languages
Polish (pl)
Other versions
PL231475B1 (en
Inventor
Bogdan Boduszek
Tomasz Olszewski
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL417694A priority Critical patent/PL231475B1/en
Publication of PL417694A1 publication Critical patent/PL417694A1/en
Publication of PL231475B1 publication Critical patent/PL231475B1/en

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Abstract

Przedmiotem zgłoszenia są kwasy ?-aminofosfonowe pochodne acetylopirydyny o wzorze ogólnym 1, w którym Het oznacza pierścień pirydynowy podstawiony w pozycji 2, 3 lub 4 oraz sposób ich wytwarzania. Sposób charakteryzuje się tym, że w pierwszym etapie bromotrimetylosilan poddaje się reakcji z fosforynem trimetylowym przy stosunku molowym bromotrimetylosilanu do fosforynu trimetylowego równym 4 do 1, a wytworzony in situ fosforyn tris(trimetylosilylowy) poddaje się następnie reakcji addycji z ketiminami pirydynowymi, a potem odparowuje się rozpuszczalnik i pozostałość rozpuszcza się w alkoholu metylowym, z którego wydziela się pożądane kwasy ?-aminofosfonowe.The subject of the application are α-aminophosphonic acids of acetylpyridine of general formula 1, in which Het is a pyridine ring substituted in the 2, 3 or 4 position and the method of their preparation. The method is characterized in that in the first stage bromotrimethylsilane is reacted with trimethyl phosphite at a molar ratio of bromotrimethylsilane to trimethyl phosphite equal to 4 to 1, and the in situ formed tris (trimethylsilyl) phosphite is then reacted with pyridine ketimines and then evaporated the solvent and residue are dissolved in methyl alcohol, from which the desired α-aminophosphonic acids are separated.

PL417694A 2016-06-23 2016-06-23 α-aminophosphonic acids originating from acetylpyridine and method for producing it PL231475B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL417694A PL231475B1 (en) 2016-06-23 2016-06-23 α-aminophosphonic acids originating from acetylpyridine and method for producing it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL417694A PL231475B1 (en) 2016-06-23 2016-06-23 α-aminophosphonic acids originating from acetylpyridine and method for producing it

Publications (2)

Publication Number Publication Date
PL417694A1 true PL417694A1 (en) 2017-02-27
PL231475B1 PL231475B1 (en) 2019-02-28

Family

ID=58092013

Family Applications (1)

Application Number Title Priority Date Filing Date
PL417694A PL231475B1 (en) 2016-06-23 2016-06-23 α-aminophosphonic acids originating from acetylpyridine and method for producing it

Country Status (1)

Country Link
PL (1) PL231475B1 (en)

Also Published As

Publication number Publication date
PL231475B1 (en) 2019-02-28

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