PL418713A1 - Przeciwnowotworowe białko fuzyjne - Google Patents
Przeciwnowotworowe białko fuzyjneInfo
- Publication number
- PL418713A1 PL418713A1 PL418713A PL41871316A PL418713A1 PL 418713 A1 PL418713 A1 PL 418713A1 PL 418713 A PL418713 A PL 418713A PL 41871316 A PL41871316 A PL 41871316A PL 418713 A1 PL418713 A1 PL 418713A1
- Authority
- PL
- Poland
- Prior art keywords
- antineoplastic
- fusion protein
- oncostatin
- fragment
- fusion proteins
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title abstract 2
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 230000000118 anti-neoplastic effect Effects 0.000 title 1
- 108090000630 Oncostatin M Proteins 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 3
- 102000004140 Oncostatin M Human genes 0.000 abstract 2
- 101000992170 Homo sapiens Oncostatin-M Proteins 0.000 abstract 1
- 108700033844 Pseudomonas aeruginosa toxA Proteins 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 102000043703 human OSM Human genes 0.000 abstract 1
- 238000011275 oncology therapy Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5412—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Zgłoszenie dotyczy dziedziny terapeutycznych rekombinowanych białek fuzyjnych. Konkretnie, zgłoszenie dotyczy białek fuzyjnych egzotoksyny A Pseudomonas w połączeniu z fragmentem ludzkiej onkostatyny M (OSM) lub mutantem fragmentu onkostatyny M, mutanta fragmentu onkostatyny M oraz ich zastosowania w terapii przeciwnowotworowej.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL418713A PL233352B1 (pl) | 2016-09-15 | 2016-09-15 | Przeciwnowotworowe białko fuzyjne |
| EP17777504.6A EP3512562B1 (en) | 2016-09-15 | 2017-09-15 | Antineoplastic fusion protein |
| PCT/EP2017/073245 WO2018050808A1 (en) | 2016-09-15 | 2017-09-15 | Antineoplastic fusion protein |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL418713A PL233352B1 (pl) | 2016-09-15 | 2016-09-15 | Przeciwnowotworowe białko fuzyjne |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL418713A1 true PL418713A1 (pl) | 2018-03-26 |
| PL233352B1 PL233352B1 (pl) | 2019-10-31 |
Family
ID=59997318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL418713A PL233352B1 (pl) | 2016-09-15 | 2016-09-15 | Przeciwnowotworowe białko fuzyjne |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP3512562B1 (pl) |
| PL (1) | PL233352B1 (pl) |
| WO (1) | WO2018050808A1 (pl) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9931386B2 (en) * | 2008-06-16 | 2018-04-03 | Atsuo Ochi | Recombinant multiple domain fusion protein mitogens and use thereof for inducing enhancement or repression of antigen-specific immunity |
| PL397167A1 (pl) * | 2011-11-28 | 2013-06-10 | Adamed Spólka Z Ograniczona Odpowiedzialnoscia | Przeciwnowotworowe bialko fuzyjne |
| WO2013178783A1 (en) * | 2012-06-01 | 2013-12-05 | Ablynx N.V. | P2x7 receptor antagonists and agonists |
| KR20250058773A (ko) * | 2015-09-11 | 2025-04-30 | 바이오셉터 (어스트) 피티와이 엘티디 | 키메라 항원 수용체 및 이의 용도 |
| WO2017193059A1 (en) * | 2016-05-06 | 2017-11-09 | The Regents Of The University Of California | Systems and methods for targeting cancer cells |
-
2016
- 2016-09-15 PL PL418713A patent/PL233352B1/pl unknown
-
2017
- 2017-09-15 WO PCT/EP2017/073245 patent/WO2018050808A1/en not_active Ceased
- 2017-09-15 EP EP17777504.6A patent/EP3512562B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PL233352B1 (pl) | 2019-10-31 |
| WO2018050808A1 (en) | 2018-03-22 |
| EP3512562B1 (en) | 2021-06-30 |
| EP3512562A1 (en) | 2019-07-24 |
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