PL4203959T3 - Kompozycja zawierająca tTF-NGR do zastosowania w leczeniu mięsaka tkanek miękkich - Google Patents

Kompozycja zawierająca tTF-NGR do zastosowania w leczeniu mięsaka tkanek miękkich

Info

Publication number
PL4203959T3
PL4203959T3 PL21766458.0T PL21766458T PL4203959T3 PL 4203959 T3 PL4203959 T3 PL 4203959T3 PL 21766458 T PL21766458 T PL 21766458T PL 4203959 T3 PL4203959 T3 PL 4203959T3
Authority
PL
Poland
Prior art keywords
ngr
ttf
composition
tissue sarcoma
treating soft
Prior art date
Application number
PL21766458.0T
Other languages
English (en)
Inventor
Wolfgang E. Berdel
Original Assignee
Anturec Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anturec Pharmaceuticals Gmbh filed Critical Anturec Pharmaceuticals Gmbh
Publication of PL4203959T3 publication Critical patent/PL4203959T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/488—Aspartic endopeptidases (3.4.23), e.g. pepsin, chymosin, renin, cathepsin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485—Exopeptidases (3.4.11-3.4.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/11—Aminopeptidases (3.4.11)
    • C12Y304/11002—Membrane alanyl aminopeptidase (3.4.11.2), i.e. aminopeptidase N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
PL21766458.0T 2020-08-26 2021-08-23 Kompozycja zawierająca tTF-NGR do zastosowania w leczeniu mięsaka tkanek miękkich PL4203959T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20192984.1A EP3960177A1 (en) 2020-08-26 2020-08-26 Composition comprising ttf-ngr for use in treating soft-tissue sarcoma
PCT/EP2021/073234 WO2022043245A1 (en) 2020-08-26 2021-08-23 Composition comprising ttf-ngr for use in treating soft-tissue sarcoma

Publications (1)

Publication Number Publication Date
PL4203959T3 true PL4203959T3 (pl) 2025-01-13

Family

ID=72266146

Family Applications (1)

Application Number Title Priority Date Filing Date
PL21766458.0T PL4203959T3 (pl) 2020-08-26 2021-08-23 Kompozycja zawierająca tTF-NGR do zastosowania w leczeniu mięsaka tkanek miękkich

Country Status (15)

Country Link
US (1) US12533399B2 (pl)
EP (2) EP3960177A1 (pl)
JP (1) JP7823028B2 (pl)
KR (1) KR20230058113A (pl)
CN (1) CN116600809B (pl)
AU (1) AU2021334093A1 (pl)
BR (1) BR112023000604A2 (pl)
CA (1) CA3185193A1 (pl)
ES (1) ES2999132T3 (pl)
HR (1) HRP20241253T1 (pl)
HU (1) HUE069051T2 (pl)
MX (1) MX2023002094A (pl)
PL (1) PL4203959T3 (pl)
RS (1) RS65936B1 (pl)
WO (1) WO2022043245A1 (pl)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY164077A (en) 1999-05-13 2017-11-30 Pharma Mar Sa Compositions and uses of et743 for treating cancer
WO2002036135A2 (en) 2000-11-06 2002-05-10 Pharma Mar, S.A. Compositions for antitumour treatment containing ecteinascidin 743
DE10338733A1 (de) * 2003-08-22 2005-03-24 Berdel, Wolfgang E., Prof. Dr.med. Fusionspolypeptide und deren Verwendung für die antivaskuläre Tumortherapie
JP2009517403A (ja) * 2005-11-25 2009-04-30 ユニバーシティー オブ メディシン アンド デンティストリー オブ ニュージャージー Parp−1阻害剤の使用
GB201217439D0 (en) * 2012-09-28 2012-11-14 Topotarget As Combination therapy

Also Published As

Publication number Publication date
WO2022043245A1 (en) 2022-03-03
HUE069051T2 (hu) 2025-02-28
BR112023000604A2 (pt) 2023-03-14
CN116600809A (zh) 2023-08-15
EP4203959C0 (en) 2024-08-14
US20230321205A1 (en) 2023-10-12
ES2999132T3 (en) 2025-02-24
US12533399B2 (en) 2026-01-27
CN116600809B (zh) 2025-05-02
CA3185193A1 (en) 2022-03-03
EP3960177A1 (en) 2022-03-02
AU2021334093A1 (en) 2023-02-09
KR20230058113A (ko) 2023-05-02
JP2023539578A (ja) 2023-09-15
JP7823028B2 (ja) 2026-03-03
RS65936B1 (sr) 2024-10-31
EP4203959B1 (en) 2024-08-14
MX2023002094A (es) 2023-03-15
HRP20241253T1 (hr) 2024-12-06
EP4203959A1 (en) 2023-07-05

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