PL421532A1 - System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii - Google Patents

System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii

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Publication number
PL421532A1
PL421532A1 PL421532A PL42153217A PL421532A1 PL 421532 A1 PL421532 A1 PL 421532A1 PL 421532 A PL421532 A PL 421532A PL 42153217 A PL42153217 A PL 42153217A PL 421532 A1 PL421532 A1 PL 421532A1
Authority
PL
Poland
Prior art keywords
implant
module
subcutaneous
electric field
powered
Prior art date
Application number
PL421532A
Other languages
English (en)
Inventor
Marta MICHALCZYK
Kamil ADAMCZYK
Janusz FRĄCZEK
Original Assignee
Michalczyk Marta
Adamczyk Kamil
Frączek Janusz Stanisław
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michalczyk Marta, Adamczyk Kamil, Frączek Janusz Stanisław filed Critical Michalczyk Marta
Priority to PL421532A priority Critical patent/PL421532A1/pl
Priority to US16/612,136 priority patent/US20210077800A1/en
Priority to EP18733673.0A priority patent/EP3634572A1/en
Priority to PCT/IB2018/053210 priority patent/WO2018207103A1/en
Publication of PL421532A1 publication Critical patent/PL421532A1/pl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1402—Probes for open surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00059—Material properties
    • A61B2018/00071—Electrical conductivity
    • A61B2018/00083—Electrical conductivity low, i.e. electrically insulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434—Neural system
    • A61B2018/00446—Brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00994—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0272—Electro-active or magneto-active materials
    • A61M2205/0294—Piezoelectric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8237—Charging means
    • A61M2205/8243—Charging means by induction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0693—Brain, cerebrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
    • A61N1/37223—Circuits for electromagnetic coupling
    • A61N1/37229—Shape or location of the implanted or external antenna
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/378—Electrical supply
    • A61N1/3787—Electrical supply from an external energy source
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0039—Ultrasound therapy using microbubbles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Electrotherapy Devices (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Prostheses (AREA)

Abstract

System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe lub zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii składający się z części pozaustrojowej (1) zakładanej na ogoloną głowę pacjenta oraz części wewnątrzustrojowej (2), na którą składa się moduł podskórny (10) znajdujący się pod skórą, lecz na czaszce pacjenta oraz implantu (11) znajdujący się wewnątrz czaszki w miejscu loży guza mózgu, bez fizycznego kontaktu z przestrzenią zewnątrzustrojową. Implant (11) zasilany jest przewodem wtórnym (14) (lub bezprzewodowo), który łączy implant (11) z modułem podskórnym (10), który poprzez moduł komunikacji optycznej łączy się z częścią pozaustrojową (1) dzięki odbiornikowi układu optycznego znajdującego się w module podskórnym (10). Urządzenie charakteryzuje się tym, że na lożę guza mózgu i na otaczające ją tkanki mózgu oddziałuje zmienne pole elektryczne o częstotliwości między 50 kHz, a 500 kHz oraz natężeniu pola przynajmniej 0.5 V/cm, przy czym pole elektryczne jest generowane jednocześnie w minimum dwóch kierunkach, poprzez pary elektrod tj. jedną implantową izolowaną elektrodę znajdującą się w implancie (11) i/lub izolowaną elektrodę (3) znajdującą się w części pozaustrojowej (1) w pierwotnym module TET i/lub podskórną izolowaną elektrodę znajdującą się w module podskórnym (10).
PL421532A 2017-05-08 2017-05-08 System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii PL421532A1 (pl)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PL421532A PL421532A1 (pl) 2017-05-08 2017-05-08 System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii
US16/612,136 US20210077800A1 (en) 2017-05-08 2018-05-08 A system and a method for treating tumors, especially intracranial tumors
EP18733673.0A EP3634572A1 (en) 2017-05-08 2018-05-08 A system and a method for treating tumors, especially intracranial tumors
PCT/IB2018/053210 WO2018207103A1 (en) 2017-05-08 2018-05-08 A system and a method for treating tumors, especially intracranial tumors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL421532A PL421532A1 (pl) 2017-05-08 2017-05-08 System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii

Publications (1)

Publication Number Publication Date
PL421532A1 true PL421532A1 (pl) 2018-11-19

Family

ID=62713035

Family Applications (1)

Application Number Title Priority Date Filing Date
PL421532A PL421532A1 (pl) 2017-05-08 2017-05-08 System do leczenia nowotworów wewnątrzczaszkowych z wykorzystaniem implantu, generującego ciągłe, zmienne pole elektryczne oraz ultradźwięki, zasilanego metodą przezskórnego transferu energii

Country Status (4)

Country Link
US (1) US20210077800A1 (pl)
EP (1) EP3634572A1 (pl)
PL (1) PL421532A1 (pl)
WO (1) WO2018207103A1 (pl)

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US12403306B2 (en) 2017-10-23 2025-09-02 Cardiac Pacemakers, Inc. Electric field shaping leads for treatment of cancer
US11338135B2 (en) 2017-10-23 2022-05-24 Cardiac Pacemakers, Inc. Medical devices for cancer therapy with electric field shaping elements
CN112930209B (zh) 2018-10-15 2024-10-15 诺沃库勒有限责任公司 生成遍及大脑具有高均匀性的肿瘤治疗场(ttfields)的装置和方法
US12109412B2 (en) 2019-04-22 2024-10-08 Boston Scientific Scimed, Inc. Combination electrical and chemotherapeutic treatment of cancer
WO2020219337A1 (en) 2019-04-22 2020-10-29 Boston Scientific Scimed, Inc. Systems for administering electrical stimulation to treat cancer
CN113727753B (zh) 2019-04-22 2024-09-13 波士顿科学国际有限公司 用于癌症治疗的电刺激装置
US11712561B2 (en) 2019-04-23 2023-08-01 Boston Scientific Scimed, Inc. Electrical stimulation with thermal treatment or thermal monitoring
US11607542B2 (en) 2019-04-23 2023-03-21 Boston Scientific Scimed, Inc. Electrical stimulation for cancer treatment with internal and external electrodes
WO2020219519A1 (en) 2019-04-23 2020-10-29 Boston Scientific Scimed, Inc. Electrodes for electrical stimulation to treat cancer
JP7472264B2 (ja) * 2019-07-31 2024-04-22 ノボキュア ゲーエムベーハー 頭蓋骨インプラントに埋め込まれた電極による腫瘍治療電場（ｔｔフィールド）の印加
WO2021102356A1 (en) * 2019-11-20 2021-05-27 Berg Llc Combination therapy of a coenzyme q10 compound and radiation therapy for treatment of glioma
EP4061477B1 (en) * 2019-11-21 2023-09-06 Novocure GmbH Implantable arrays for providing tumor treating fields
CN115515674A (zh) 2020-02-24 2022-12-23 波士顿科学国际有限公司 用于治疗胰腺癌的系统和方法
TWI885157B (zh) 2020-06-02 2025-06-01 瑞士商諾沃庫勒有限責任公司 用於產生電場之設備及方法
CN113230538A (zh) * 2021-06-16 2021-08-10 华健医疗(深圳)有限公司 一种交变电场肿瘤治疗装置
CN114788727A (zh) * 2021-12-01 2022-07-26 武汉拓扑转化医学研究中心有限公司 脑肿瘤脉冲电场治疗系统
US20250177764A1 (en) * 2021-12-22 2025-06-05 Jiangsu Healthy Life Innovation Medical Technology Co., Ltd Tumor treating field system and method for applying alternating current signals thereof
CN114225215B (zh) * 2021-12-31 2023-05-05 湖南安泰康成生物科技有限公司 电极系统
CN115227965A (zh) * 2022-06-23 2022-10-25 中山大学 一种基于声电转换的超薄脑部胶质瘤治疗芯片及系统
WO2024159155A1 (en) * 2023-01-26 2024-08-02 The Brigham And Women's Hospital, Inc. Devices for intracavity tumor treating fields
CN119607411A (zh) * 2024-11-01 2025-03-14 北京建筑大学 超声电场耦合治疗柔性器件及其制备方法

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Also Published As

Publication number Publication date
WO2018207103A4 (en) 2019-01-03
US20210077800A1 (en) 2021-03-18
WO2018207103A1 (en) 2018-11-15
EP3634572A1 (en) 2020-04-15

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