PL423720A1 - Sweetening system of the oral pharmaceutical composition that contains hydrochloride fenspiride and the pharmaceutical composition that contains this system - Google Patents
Sweetening system of the oral pharmaceutical composition that contains hydrochloride fenspiride and the pharmaceutical composition that contains this systemInfo
- Publication number
- PL423720A1 PL423720A1 PL423720A PL42372017A PL423720A1 PL 423720 A1 PL423720 A1 PL 423720A1 PL 423720 A PL423720 A PL 423720A PL 42372017 A PL42372017 A PL 42372017A PL 423720 A1 PL423720 A1 PL 423720A1
- Authority
- PL
- Poland
- Prior art keywords
- pharmaceutical composition
- fenspiride
- hydrochloride
- sweetening
- oral pharmaceutical
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- FVNFBBAOMBJTST-UHFFFAOYSA-N 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one Chemical compound O1C(=O)NCC11CCN(CCC=2C=CC=CC=2)CC1 FVNFBBAOMBJTST-UHFFFAOYSA-N 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
- 229960002912 fenspiride Drugs 0.000 title 1
- 239000008203 oral pharmaceutical composition Substances 0.000 title 1
- 239000001512 FEMA 4601 Substances 0.000 abstract 2
- HELXLJCILKEWJH-SEAGSNCFSA-N Rebaudioside A Natural products O=C(O[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)[C@@]1(C)[C@@H]2[C@](C)([C@H]3[C@@]4(CC(=C)[C@@](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@H](O)[C@@H](CO)O5)(C4)CC3)CC2)CCC1 HELXLJCILKEWJH-SEAGSNCFSA-N 0.000 abstract 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 2
- 229930006000 Sucrose Natural products 0.000 abstract 2
- HELXLJCILKEWJH-UHFFFAOYSA-N entered according to Sigma 01432 Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC(C1OC2C(C(O)C(O)C(CO)O2)O)OC(CO)C(O)C1OC1OC(CO)C(O)C(O)C1O HELXLJCILKEWJH-UHFFFAOYSA-N 0.000 abstract 2
- 235000003599 food sweetener Nutrition 0.000 abstract 2
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 abstract 2
- 235000019203 rebaudioside A Nutrition 0.000 abstract 2
- 239000005720 sucrose Substances 0.000 abstract 2
- 239000003765 sweetening agent Substances 0.000 abstract 2
- FIKFLLIUPUVONI-UHFFFAOYSA-N 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one;hydrochloride Chemical compound Cl.O1C(=O)NCC11CCN(CCC=2C=CC=CC=2)CC1 FIKFLLIUPUVONI-UHFFFAOYSA-N 0.000 abstract 1
- 229960000695 fenspiride hydrochloride Drugs 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Zgłoszenie dotyczy układu słodzącego ciekłej doustnej kompozycji farmaceutycznej chlorowodorku fenspirydu, składającego się z sacharozy i rebaudiozydu A, w stosunku wagowym sacharozy do rebaudiozydu A w zakresie od 420:1 do 440:1. Ponadto zgłoszenie odnosi się do kompozycji farmaceutycznej zawierającej wspomniany układ słodzący w ilości od 785 mg/ml do 795 mg/ml kompozycji.The application relates to a sweetener system for the liquid pharmaceutical pharmaceutical composition fenspiride hydrochloride, consisting of sucrose and rebaudioside A, in a weight ratio of sucrose to rebaudioside A in the range from 420: 1 to 440: 1. Furthermore, the application relates to a pharmaceutical composition containing said sweetener system in an amount from 785 mg / ml to 795 mg / ml of the composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL423720A PL237234B1 (en) | 2017-12-04 | 2017-12-04 | Sweetening system of the oral pharmaceutical composition that contains hydrochloride fenspiride and the pharmaceutical composition that contains this system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL423720A PL237234B1 (en) | 2017-12-04 | 2017-12-04 | Sweetening system of the oral pharmaceutical composition that contains hydrochloride fenspiride and the pharmaceutical composition that contains this system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL423720A1 true PL423720A1 (en) | 2019-06-17 |
| PL237234B1 PL237234B1 (en) | 2021-03-22 |
Family
ID=66809703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL423720A PL237234B1 (en) | 2017-12-04 | 2017-12-04 | Sweetening system of the oral pharmaceutical composition that contains hydrochloride fenspiride and the pharmaceutical composition that contains this system |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL237234B1 (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110236551A1 (en) * | 2010-03-16 | 2011-09-29 | Imperial Sugar Company | Process for the manufacture of co-crystallized sucrose natural sweeteners and the products thereof |
| US20150237907A1 (en) * | 2006-10-24 | 2015-08-27 | Givaudan S.A. | Consumables |
-
2017
- 2017-12-04 PL PL423720A patent/PL237234B1/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150237907A1 (en) * | 2006-10-24 | 2015-08-27 | Givaudan S.A. | Consumables |
| US20110236551A1 (en) * | 2010-03-16 | 2011-09-29 | Imperial Sugar Company | Process for the manufacture of co-crystallized sucrose natural sweeteners and the products thereof |
Non-Patent Citations (2)
| Title |
|---|
| PULNEO, PULNEO, SYROP FENSPIRIDI HYDROCHLORIDUM 2MG/ML * |
| WOJCIECH KOLANOWSKI, GLIKOZYDY STEWIOLOWE - WŁAŚCIWOŚCI I ZASTOSOWANIE W ŻYWNOŚCI, 2013 * |
Also Published As
| Publication number | Publication date |
|---|---|
| PL237234B1 (en) | 2021-03-22 |
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