PL427105A1 - Hydrazyd kwasu N'-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo-2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie - Google Patents

Hydrazyd kwasu N'-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo-2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie

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Publication number
PL427105A1
PL427105A1 PL427105A PL42710518A PL427105A1 PL 427105 A1 PL427105 A1 PL 427105A1 PL 427105 A PL427105 A PL 427105A PL 42710518 A PL42710518 A PL 42710518A PL 427105 A1 PL427105 A1 PL 427105A1
Authority
PL
Poland
Prior art keywords
dimethyl
sulfanyl
acetic acid
anthracen
pyridin
Prior art date
Application number
PL427105A
Other languages
English (en)
Other versions
PL237497B1 (pl
Inventor
Piotr ŚWIĄTEK
Jolanta Saczko
Julita Kulbacka
Nina Rembiałowska
Original Assignee
Uniwersytet Medyczny Im. Piastów Śląskich We Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Medyczny Im. Piastów Śląskich We Wrocławiu filed Critical Uniwersytet Medyczny Im. Piastów Śląskich We Wrocławiu
Priority to PL427105A priority Critical patent/PL237497B1/pl
Priority to PCT/PL2019/000081 priority patent/WO2020060427A1/en
Publication of PL427105A1 publication Critical patent/PL427105A1/pl
Publication of PL237497B1 publication Critical patent/PL237497B1/pl

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Przedmiotem zgłoszenia jest nowa pochodna 4,6-dimetylo-2-sulfanylopirydyny o nazwie chemicznej hydrazyd kwasu N'-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo-2-sulfanylo-pirydyn-3-ylo-karboksamido]octowego, wykazująca aktywność przeciwnowotworową wobec wybranych komórek nowotworowych oraz sposób otrzymywania nowej pochodnej w reakcji N-(2-hydrazyno-2-oksoetylo)-4,6-dimetylo-2-sulfanylopirydyno-3-karboksamidu z 9-antracenokarboksaldehydem w środowisku wrzącego metanolu i obecności katalitycznej ilości stężonego kwasu octowego. Zgłoszenie to obejmuje też sposób wytwarzania przedmiotowej pochodnej.
PL427105A 2018-09-17 2018-09-17 Hydrazyd kwasu N’-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo- 2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie PL237497B1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL427105A PL237497B1 (pl) 2018-09-17 2018-09-17 Hydrazyd kwasu N’-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo- 2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie
PCT/PL2019/000081 WO2020060427A1 (en) 2018-09-17 2019-09-17 N'-[(anthracen-9-yl)methylene]-2-[4,6-dimethyl-2-sulphanylpyridin-3-yl-carboxamido]acetic acid hydrazide, method of its preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL427105A PL237497B1 (pl) 2018-09-17 2018-09-17 Hydrazyd kwasu N’-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo- 2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie

Publications (2)

Publication Number Publication Date
PL427105A1 true PL427105A1 (pl) 2020-03-23
PL237497B1 PL237497B1 (pl) 2021-04-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL427105A PL237497B1 (pl) 2018-09-17 2018-09-17 Hydrazyd kwasu N’-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo- 2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie

Country Status (2)

Country Link
PL (1) PL237497B1 (pl)
WO (1) WO2020060427A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102511411B (zh) * 2011-11-15 2014-05-21 河北省海洋与水产科学研究院 一种环保海水池塘生态养殖方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2824876A (en) * 1955-02-23 1958-02-25 Schenley Ind Inc Production of 4-mercaptonicotinic acid and intermediate therefor
TW200426138A (en) * 2002-12-10 2004-12-01 Hoffmann La Roche Novel arylene-carboxylic acid (2-amino-phenyl)-amide derivatives, their manufacture and use as pharmaceutical agents
BRPI0507757A (pt) * 2004-02-17 2007-07-10 Santen Pharmaceutical Co Ltd composto, composição farmacêutica, e agente terapêutico para uma doença na qual a angiogênese ou a hipermeabilidade vascular está envolvida
ES2351613T3 (es) * 2005-03-03 2011-02-08 Santen Pharmaceutical Co., Ltd. Nuevo compuesto cíclico que tiene un grupo quinolilalquiltio.

Also Published As

Publication number Publication date
WO2020060427A1 (en) 2020-03-26
PL237497B1 (pl) 2021-04-19

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