PL427105A1 - Hydrazyd kwasu N'-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo-2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie - Google Patents

Hydrazyd kwasu N'-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo-2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie

Info

Publication number
PL427105A1
PL427105A1 PL427105A PL42710518A PL427105A1 PL 427105 A1 PL427105 A1 PL 427105A1 PL 427105 A PL427105 A PL 427105A PL 42710518 A PL42710518 A PL 42710518A PL 427105 A1 PL427105 A1 PL 427105A1
Authority
PL
Poland
Prior art keywords
dimethyl
sulfanyl
acetic acid
anthracen
pyridin
Prior art date
Application number
PL427105A
Other languages
English (en)
Other versions
PL237497B1 (pl
Inventor
Piotr ŚWIĄTEK
Jolanta Saczko
Julita Kulbacka
Nina Rembiałowska
Original Assignee
Uniwersytet Medyczny Im. Piastów Śląskich We Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Medyczny Im. Piastów Śląskich We Wrocławiu filed Critical Uniwersytet Medyczny Im. Piastów Śląskich We Wrocławiu
Priority to PL427105A priority Critical patent/PL237497B1/pl
Priority to PCT/PL2019/000081 priority patent/WO2020060427A1/en
Publication of PL427105A1 publication Critical patent/PL427105A1/pl
Publication of PL237497B1 publication Critical patent/PL237497B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Przedmiotem zgłoszenia jest nowa pochodna 4,6-dimetylo-2-sulfanylopirydyny o nazwie chemicznej hydrazyd kwasu N'-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo-2-sulfanylo-pirydyn-3-ylo-karboksamido]octowego, wykazująca aktywność przeciwnowotworową wobec wybranych komórek nowotworowych oraz sposób otrzymywania nowej pochodnej w reakcji N-(2-hydrazyno-2-oksoetylo)-4,6-dimetylo-2-sulfanylopirydyno-3-karboksamidu z 9-antracenokarboksaldehydem w środowisku wrzącego metanolu i obecności katalitycznej ilości stężonego kwasu octowego. Zgłoszenie to obejmuje też sposób wytwarzania przedmiotowej pochodnej.
PL427105A 2018-09-17 2018-09-17 Hydrazyd kwasu N’-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo- 2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie PL237497B1 (pl)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL427105A PL237497B1 (pl) 2018-09-17 2018-09-17 Hydrazyd kwasu N’-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo- 2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie
PCT/PL2019/000081 WO2020060427A1 (en) 2018-09-17 2019-09-17 N'-[(anthracen-9-yl)methylene]-2-[4,6-dimethyl-2-sulphanylpyridin-3-yl-carboxamido]acetic acid hydrazide, method of its preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL427105A PL237497B1 (pl) 2018-09-17 2018-09-17 Hydrazyd kwasu N’-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo- 2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie

Publications (2)

Publication Number Publication Date
PL427105A1 true PL427105A1 (pl) 2020-03-23
PL237497B1 PL237497B1 (pl) 2021-04-19

Family

ID=69887681

Family Applications (1)

Application Number Title Priority Date Filing Date
PL427105A PL237497B1 (pl) 2018-09-17 2018-09-17 Hydrazyd kwasu N’-[(antracen-9-ylo)metyleno]-2-[4,6-dimetylo- 2-sulfanylopirydyn-3-ylo-karboksamido]octowego, sposób jego otrzymywania i zastosowanie

Country Status (2)

Country Link
PL (1) PL237497B1 (pl)
WO (1) WO2020060427A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102511411B (zh) * 2011-11-15 2014-05-21 河北省海洋与水产科学研究院 一种环保海水池塘生态养殖方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2824876A (en) * 1955-02-23 1958-02-25 Schenley Ind Inc Production of 4-mercaptonicotinic acid and intermediate therefor
TW200426138A (en) * 2002-12-10 2004-12-01 Hoffmann La Roche Novel arylene-carboxylic acid (2-amino-phenyl)-amide derivatives, their manufacture and use as pharmaceutical agents
ATE512950T1 (de) * 2004-02-17 2011-07-15 Santen Pharmaceutical Co Ltd Neue cyclische verbindung mit 4- pyridylalkylthiogruppe mit darin eingeführtem (un)substituiertem amino
ES2351613T3 (es) * 2005-03-03 2011-02-08 Santen Pharmaceutical Co., Ltd. Nuevo compuesto cíclico que tiene un grupo quinolilalquiltio.

Also Published As

Publication number Publication date
PL237497B1 (pl) 2021-04-19
WO2020060427A1 (en) 2020-03-26

Similar Documents

Publication Publication Date Title
Baulieu et al. STUDIES ON TESTOSTERONE METABOLISM. I. CONVERSION OF TESTOSTERONE-17-ALPHA-3H TO 5-ALPHA-AND 5-BETA-ANDROSTANE-3-ALPHA, 17-BETA-DEOL-17-ALPHA-3H: A NEW" 17-BETA-HYDROXYL PATHWAY"
Abrol et al. Studies on the identification, biosynthesis and metabolism of a cyanogenic glucoside in Nandina domestica Thunb.
DK1149070T3 (da) Fremgangsmåde til fremstilling af methylcarbazat
Knoch et al. Ozone-oxygen therapy in proctology
Richman et al. Continuous in-vivo blood-gas determination in man: reliability and safety of a new device.
Basset et al. Contribution of the renin-angiotensin system to blood pressure variability in hyperthyroid rats
JPS5334703A (en) Preparation of methyl bromide from hydrobromic acid
Murachi Enzymic synthesis of acyllysine anilides. II. Optical resolution of dl-lysine
JPS5346916A (en) Preparation of hydroxyacetic acid
藤井澄三 et al. [4, 5-Dimethoxy-α-(3, 4-dimethoxyphenyl)-o-tolyl] acetonitrile: A By-Product from the Reaction of 3, 4-Dimethoxybenzyl Chloride with Sodium Cyanide
Qi et al. Study on chemical constituents from stem of Mallotus apelta
YASHIRO et al. STUDIES ON XANTHURENIC ACID: VII. ON THE" XANTHURENICASE"
Jawdosiuk et al. Formation of α-nitro-acetylenes by the coupling reactions of lithium acetylides with 2-chloro-2-nitropropane or 2, 2-dinitropropane
GB821400A (en) Process of nitrosation
JPS5433682A (en) Semiconductor displacement converter
CN203493360U (zh) 石榴剥皮器
Mottard et al. Hemodynamic monitoring and mortality.
MD2398G2 (ro) Cobaltatul de lantan în calitate de catalizator de radioliză a apei
CN202036269U (zh) 一种搭扣式瘘口保护带
Moss et al. The preparation of 2-ethoxy-4, 5-diphenyl-1, 3-dioxole and its conversion into diphenylethyne and diphenylketen
Helphrey Synthesis of Novel Tyrosine Derivatives of Temozolomide and Their Biological Evaluation Against Breast Cancer Cells
KUGA Studies on the method of silk-reeling at the low temperature (I) On the killing method of pupa of Bombyx mori by HCN gas
FR2086501A1 (en) Herbicidal dihalophenyl-ureas
Ramachandran et al. Piperlongumine, a novel treatment option to overcome BRAF inhibitor resistance in melanoma
IMADATE A new species of the genus Gracilentulus (Protura, Acerentomidae) from Tsushima Islands, Japan