PL428441A1 - (4-Oxothiazolidine-5-ylidene)acetic acid derivatives, method of their preparation, their medical application and a pharmaceutical composition
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(4-Oxothiazolidine-5-ylidene)acetic acid derivatives, method of their preparation, their medical application and a pharmaceutical composition
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Application filed by Uniwersytet Medyczny W Lublinie, Uniwersytet ŁódzkifiledCriticalUniwersytet Medyczny W Lublinie
Priority to PL428441ApriorityCriticalpatent/PL237514B1/en
Publication of PL428441A1publicationCriticalpatent/PL428441A1/en
Publication of PL237514B1publicationCriticalpatent/PL237514B1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
Przedmiotem zgłoszenia są pochodne kwasu (4-oksotiazolidyn-5-ylideno)octowego o wzorze ogólnym 1 przedstawionym na rysunku, gdzie R oznacza 4-HO-C6H4, 4-HO-3-CH3O-C6H3, 3-C2H5O-4-HO-C6H3, 3-CI-4-HO-C6H3 i 3-Br-4-HO-C6H3. Zgłoszenie obejmuje też sposób otrzymywania powyższych związków oraz kompozycje farmaceutyczną, która je zawiera.The subject of the application are (4-oxothiazolidin-5-ylidene) acetic acid derivatives of the general formula 1 shown in the figure, where R is 4-HO-C6H4, 4-HO-3-CH3O-C6H3, 3-C2H5O-4-HO- C6H3, 3-CI-4-HO-C6H3 and 3-Br-4-HO-C6H3. The application also includes a method of preparing the above compounds and a pharmaceutical composition containing them.
PL428441A2018-12-312018-12-31(4-Oxothiazolidine-5-ylidene)acetic acid derivatives, method of their preparation, their medical application and a pharmaceutical composition
PL237514B1
(en)
compound of formula (i), pharmaceutical composition, method for treating and / or preventing a proliferative disease and for inhibiting or differentiating growth of a cancer stem cell
compound, use thereof, pharmaceutical composition, aerosol pharmaceutical formulation, method for treating a human or animal patient with an anti-inflammatory and / or allergic condition, and process for preparing a compound.