PL431093A1 - Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów - Google Patents

Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów

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Publication number
PL431093A1
PL431093A1 PL431093A PL43109319A PL431093A1 PL 431093 A1 PL431093 A1 PL 431093A1 PL 431093 A PL431093 A PL 431093A PL 43109319 A PL43109319 A PL 43109319A PL 431093 A1 PL431093 A1 PL 431093A1
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Poland
Prior art keywords
bioreceptor
viruses
bioreceptor molecules
molecules
electrode
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PL431093A
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English (en)
Inventor
Izabela Załuska
Joanna KRECZKO
Piotr BARSKI
Dawid NIDZWORSKI
Elżbieta CZACZYK
Tomasz ŁĘGA
Karolina DZIĄBOWSKA
Krzysztof Urbański
Maciej SASOWSKI
Wioletta BIAŁOBRZESKA
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Sensdx Spółka Akcyjna
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Priority to PL431093A priority Critical patent/PL431093A1/pl
Priority to PCT/IB2020/056746 priority patent/WO2021048646A1/en
Priority to US17/641,342 priority patent/US20220365085A1/en
Priority to EP20768381.4A priority patent/EP4028410A1/en
Priority to PCT/IB2020/058364 priority patent/WO2021048750A1/en
Publication of PL431093A1 publication Critical patent/PL431093A1/pl

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/026Dielectric impedance spectroscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Przedmiotem wynalazku jest cząsteczka bioreceptora o podanym poniżej wzorze R1-alkil-C(O)NH-R2. Kolejnym przedmiotem wynalazku jest zastosowanie cząsteczek bioreceptora według wynalazku w elektrochemicznej spektroskopii impedancyjnej do wykrywania w jednej próbce jednej lub więcej patogennych bakterii i wirusów. Zgłoszenie, niniejsze, obejmuje też czujnik zawierający elektrodę, której powierzchnia jest pokryta warstwą metalu, charakteryzujący się tym, że warstwa ta jest modyfikowana cząsteczkami bioreceptora według wynalazku. Ponadto, przedmiotem wynalazku jest też sposób wykrywania w jednej próbce jednej lub więcej patogennych bakterii i wirusów za pomocą elektrochemicznej spektroskopii impedancyjnej, obejmujący następujące etapy: przemywanie i suszenie czujnika zawierającego elektrodę pokrytą metalem, modyfikacja powierzchni czujnika zawierającego elektrodę cząsteczkami bioreceptora, kalibracja układu pomiarowego, wykrywanie w jednej próbce jednej lub więcej patogennych bakterii i wirusów za pomocą układu pomiarowego przez obserwację zmian impedancji, charakteryzujący się tym, że modyfikację powierzchni czujnika zawierającego elektrodę przeprowadza się za pomocą cząsteczki bioreceptora według wynalazku.
PL431093A 2019-09-09 2019-09-09 Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów PL431093A1 (pl)

Priority Applications (5)

Application Number Priority Date Filing Date Title
PL431093A PL431093A1 (pl) 2019-09-09 2019-09-09 Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów
PCT/IB2020/056746 WO2021048646A1 (en) 2019-09-09 2020-07-17 Bioreceptor molecules, the use of bioreceptor molecules, sensors containing electrodes modified with the said bioreceptor molecules and the detection method of sars-cov-2 virus
US17/641,342 US20220365085A1 (en) 2019-09-09 2020-07-17 Bioreceptor molecules, the use of bioreceptor molecules, sensors containing electrodes modified with the said bioreceptor molecules and the detection method of sars-cov-2 virus
EP20768381.4A EP4028410A1 (en) 2019-09-09 2020-07-17 Bioreceptor molecules, the use of bioreceptor molecules, sensors containing electrodes modified with the said bioreceptor molecules and the detection method of sars-cov-2 virus
PCT/IB2020/058364 WO2021048750A1 (en) 2019-09-09 2020-09-09 Bioreceptor molecules, the use of bioreceptor molecules, sensors containing electrodes modified by the said bioreceptor molecules, and method of detecting bacteria and viruses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL431093A PL431093A1 (pl) 2019-09-09 2019-09-09 Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów

Publications (1)

Publication Number Publication Date
PL431093A1 true PL431093A1 (pl) 2021-03-22

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PL431093A PL431093A1 (pl) 2019-09-09 2019-09-09 Cząsteczki bioreceptora, zastosowanie cząsteczek bioreceptora, czujniki zawierające elektrody modyfikowane tymi cząsteczkami bioreceptora, oraz sposób wykrywania bakterii i wirusów

Country Status (4)

Country Link
US (1) US20220365085A1 (pl)
EP (1) EP4028410A1 (pl)
PL (1) PL431093A1 (pl)
WO (2) WO2021048646A1 (pl)

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WO2023048151A1 (ja) * 2021-09-22 2023-03-30 塩野義製薬株式会社 ウイルス増殖阻害活性を有する環状ペプチド
WO2023162620A1 (ja) * 2022-02-28 2023-08-31 富士フイルム株式会社 イムノクロマトグラフキット
IN202221051330A (pl) * 2022-09-08 2023-03-31
EP4627103A1 (en) * 2022-11-30 2025-10-08 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Impedimetric detection using peptide and peptide mixtures
AU2024323118A1 (en) * 2023-08-10 2026-03-19 Adelaide university Separation of minerals using short peptides or mimetics thereof
CN119019506B (zh) * 2024-08-20 2025-09-12 东北农业大学 抗ihn病毒的亲和肽及其应用

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WO2001090149A2 (en) * 2000-05-22 2001-11-29 Pharmacia & Upjohn Company G protein-coupled receptors
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
JP2005528887A (ja) 2002-01-31 2005-09-29 エクスプレッシブ コンストラクツ,インコーポレイテッド 微生物の検出方法
CN101123990A (zh) * 2004-10-01 2008-02-13 Mida科技有限公司 包含抗原和佐剂的纳米颗粒,和免疫原性结构
EP1919507A2 (en) * 2005-08-04 2008-05-14 Thomas William Rademacher Nanoparticles comprising antibacterial ligands
CA2646987C (en) 2006-03-09 2014-09-30 The Regents Of The University Of California Method and apparatus for target detection using electrode-bound viruses
US8993245B2 (en) 2008-11-21 2015-03-31 Mediomics, Llc Biosensor for detecting multiple epitopes on a target
US20110171749A1 (en) 2009-03-02 2011-07-14 Board Of Trustees Of Michigan State University Nanoparticle tracer-based electrochemical dna sensor for detection of pathogens-amplification by a universal nano-tracer (aunt)
PL239378B1 (pl) * 2018-02-07 2021-11-29 Sensdx Spolka Z Ograniczona Odpowiedzialnoscia Czujnik do pomiarów impedancyjnych próbki czynnika biologicznego lub chemicznego oraz sposób wykrywania czynnika biologicznego lub chemicznego w próbce za pomocą takiego czujnika

Also Published As

Publication number Publication date
WO2021048646A1 (en) 2021-03-18
WO2021048750A1 (en) 2021-03-18
EP4028410A1 (en) 2022-07-20
US20220365085A1 (en) 2022-11-17

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