PL4349407T3 - 5-metoksy-n,n-dimetylotryptamina (5-meo-dmt) do leczenia depresji dużej - Google Patents

5-metoksy-n,n-dimetylotryptamina (5-meo-dmt) do leczenia depresji dużej

Info

Publication number
PL4349407T3
PL4349407T3 PL24157425.0T PL24157425T PL4349407T3 PL 4349407 T3 PL4349407 T3 PL 4349407T3 PL 24157425 T PL24157425 T PL 24157425T PL 4349407 T3 PL4349407 T3 PL 4349407T3
Authority
PL
Poland
Prior art keywords
dimethyltryptamine
dmt
meo
methoxy
major depression
Prior art date
Application number
PL24157425.0T
Other languages
English (en)
Inventor
Theis Terwey
Original Assignee
GH Research Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=65529503&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL4349407(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by GH Research Ireland Limited filed Critical GH Research Ireland Limited
Publication of PL4349407T3 publication Critical patent/PL4349407T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
PL24157425.0T 2019-02-22 2020-02-24 5-metoksy-n,n-dimetylotryptamina (5-meo-dmt) do leczenia depresji dużej PL4349407T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19158774 2019-02-22

Publications (1)

Publication Number Publication Date
PL4349407T3 true PL4349407T3 (pl) 2025-07-21

Family

ID=65529503

Family Applications (2)

Application Number Title Priority Date Filing Date
PL20710059.5T PL3927337T3 (pl) 2019-02-22 2020-02-24 5-metoksy-n,n-dimetylotryptamina (5-meo-dmt) do leczenia depresji dużej
PL24157425.0T PL4349407T3 (pl) 2019-02-22 2020-02-24 5-metoksy-n,n-dimetylotryptamina (5-meo-dmt) do leczenia depresji dużej

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL20710059.5T PL3927337T3 (pl) 2019-02-22 2020-02-24 5-metoksy-n,n-dimetylotryptamina (5-meo-dmt) do leczenia depresji dużej

Country Status (32)

Country Link
US (2) US20220071958A1 (pl)
EP (3) EP3927337B8 (pl)
JP (2) JP7598326B2 (pl)
KR (1) KR20210154966A (pl)
CN (1) CN114555078A (pl)
AU (2) AU2020225410B2 (pl)
BR (1) BR112021016153A2 (pl)
CA (1) CA3130406A1 (pl)
CL (1) CL2021002174A1 (pl)
CO (1) CO2021010882A2 (pl)
CR (1) CR20210437A (pl)
DK (2) DK3927337T3 (pl)
DO (1) DOP2021000176A (pl)
EA (1) EA202192318A1 (pl)
EC (1) ECSP21060868A (pl)
ES (2) ES2984438T3 (pl)
FI (2) FI4349407T3 (pl)
HR (2) HRP20240532T1 (pl)
HU (2) HUE066828T2 (pl)
IL (1) IL285537A (pl)
LT (2) LT4349407T (pl)
MA (1) MA55021B1 (pl)
MD (1) MD3927337T2 (pl)
MX (2) MX2021009941A (pl)
NI (1) NI202100080A (pl)
PE (1) PE20220015A1 (pl)
PL (2) PL3927337T3 (pl)
PT (2) PT3927337T (pl)
RS (2) RS66912B1 (pl)
SI (2) SI3927337T1 (pl)
SM (1) SMT202400154T1 (pl)
WO (1) WO2020169850A1 (pl)

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FI4349407T3 (fi) 2019-02-22 2025-06-02 Gh Res Ireland Limited 5-metoksi-n,n-dimetyylitryptamiini (5-meo-dmt) vaikean masennuksen hoitoon
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US11406619B2 (en) 2020-08-28 2022-08-09 Small Pharma Ltd Injectable formulations
JP7422474B2 (ja) * 2020-08-28 2024-01-26 サイビン ユーケー リミテッド 注射用製剤
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CN112138028A (zh) * 2020-10-10 2020-12-29 南京中医药大学 蟾蜍色胺类物质在制备抗抑郁药物中的应用
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WO2022117640A1 (en) * 2020-12-01 2022-06-09 Small Pharma Ltd Inhalable formulations
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US12521370B2 (en) 2020-12-01 2026-01-13 Cybin Uk Ltd Inhalable formulations
US20220265582A1 (en) * 2021-02-24 2022-08-25 Universitätsspital Basel Effects of mescaline and of mescaline analogs (scalines) to assist psychotherapy
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JP2024517738A (ja) 2021-04-26 2024-04-23 アタイ セラピューティクス, インコーポレイテッド 新規のn,n-ジメチルトリプタミン組成物および方法
EP4329759A4 (en) 2021-04-30 2025-07-16 Mind Medicine Inc CRYSTALLINE FORMS OF LSD SALTS
JP2024517194A (ja) * 2021-05-03 2024-04-19 マインド メディシン, インコーポレイテッド サイケデリック薬の用量を漸増する方法
WO2022235927A1 (en) * 2021-05-05 2022-11-10 Gilgamesh Pharmaceuticals, Inc. Novel tryptamines and methods of treating mood disorders
CA3218110A1 (en) 2021-05-25 2022-12-01 Majed Fawaz New n,n-dimethyltryptamine salts and crystalline salt forms
AU2022287974A1 (en) 2021-06-09 2024-01-04 Atai Therapeutics, Inc. Novel prodrugs and conjugates of dimethyltryptamine
JP7846211B2 (ja) 2021-08-19 2026-04-14 デフィニウム セラピューティクス ユーエス, インコーポレイテッド 治療適用のためのd-リゼルグ酸ジエチルアミドの即時放出製剤
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EP4433049A1 (en) * 2021-11-18 2024-09-25 Cybin UK Ltd Injectable and inhalable formulations
US12318477B2 (en) 2021-11-18 2025-06-03 Cybin Uk Ltd Injectable and inhalable formulations
WO2023129956A2 (en) 2021-12-30 2023-07-06 ATAI Life Sciences AG Dimethyltryptamine analogues as nitric oxide delivery drugs
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WO2023186837A1 (en) 2022-03-27 2023-10-05 GH Research Ireland Limited Treatment of postnatal depression
IL315899A (en) 2022-03-27 2024-11-01 Gh Res Ireland Limited 5-METHOXY-N,N-DIMETHYLTRYPTamine for the treatment of social/emotional withdrawal or withdrawal
WO2023186834A1 (en) 2022-03-27 2023-10-05 GH Research Ireland Limited Crystalline hydrobromide salt of 5-meo-dmt
US12264131B2 (en) 2022-08-19 2025-04-01 Beckley Psytech Limited Pharmaceutically acceptable salts and compositions thereof
GB202212116D0 (en) 2022-08-19 2022-10-05 Beckley Psytech Ltd Pharmaceutically acceptable salts and Compositions thereof
AU2023427992A1 (en) 2023-01-30 2025-09-18 GH Research Ireland Limited Treatment of mental disorders
AU2023427437A1 (en) 2023-01-30 2025-09-18 GH Research Ireland Limited 5-methoxy-n,n-dimethyltryptamine for use in the treatment of mental disorders in breastfeeding mothers
GB202306256D0 (en) * 2023-04-27 2023-06-14 Beckley Psytech Ltd 5-Methoxy-N,N-Dimethyltryptamine Formulations
WO2024251807A1 (en) * 2023-06-08 2024-12-12 Cybin Irl Limited Companion animal treatments
US12246005B2 (en) 2023-06-13 2025-03-11 Beckley Psytech Limited 5-methoxy-n,n-dimethyltryptamine (5-MeO-DMT) formulations
WO2025068714A1 (en) * 2023-09-28 2025-04-03 Beckley Psytech Limited Pharmaceutical compositions comprising 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt)
WO2025087962A1 (en) 2023-10-23 2025-05-01 Reconnect Labs Ag Pharmaceutical formulations comprising 5-meo-dmt and their therapeutic uses
WO2025111597A1 (en) * 2023-11-22 2025-05-30 Gilgamesh Pharmaceuticals, Inc. A treatment for patients with mood disorders using n-ethyl-2-(5-fluoro-1h-indol-3-yl)- n-methylethan-1-amine or a pharmaceutically acceptable salt thereof
WO2026068951A1 (en) * 2024-09-27 2026-04-02 Beckley Psytech Limited 5-methoxy-dmt for use in the treatment of depression
WO2026078143A1 (en) 2024-10-09 2026-04-16 GH Research Ireland Limited Combinations of 5-meo-dmt with antidepressants for treating depression

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Also Published As

Publication number Publication date
AU2020225410A1 (en) 2021-08-19
EA202192318A1 (ru) 2021-12-21
PT3927337T (pt) 2024-05-17
EP4349407A3 (en) 2024-07-03
HUE071841T2 (hu) 2025-09-28
EP4353314A2 (en) 2024-04-17
ES3031965T3 (en) 2025-07-14
EP3927337B1 (en) 2024-02-14
EP3927337A1 (en) 2021-12-29
EP4349407B1 (en) 2025-04-09
RS65706B1 (sr) 2024-08-30
LT4349407T (lt) 2025-07-10
MX2025002567A (es) 2025-04-02
CR20210437A (es) 2021-11-02
AU2026200720A1 (en) 2026-02-19
BR112021016153A2 (pt) 2021-10-05
NI202100080A (es) 2021-12-06
EP3927337B8 (en) 2024-03-20
CO2021010882A2 (es) 2022-01-17
LT3927337T (lt) 2024-07-10
RS66912B1 (sr) 2025-07-31
KR20210154966A (ko) 2021-12-21
DK3927337T3 (da) 2024-04-22
PE20220015A1 (es) 2022-01-11
SI4349407T1 (sl) 2025-06-30
HRP20250590T1 (hr) 2025-07-04
EP4353314A3 (en) 2024-07-03
IL285537A (en) 2021-09-30
DK4349407T3 (da) 2025-05-26
FI3927337T3 (fi) 2024-05-08
WO2020169850A1 (en) 2020-08-27
US20220071958A1 (en) 2022-03-10
FI4349407T3 (fi) 2025-06-02
AU2020225410B2 (en) 2025-10-30
HRP20240532T1 (hr) 2024-07-19
HUE066828T2 (hu) 2024-09-28
ECSP21060868A (es) 2021-11-30
DOP2021000176A (es) 2021-11-21
MD3927337T2 (ro) 2024-08-31
CL2021002174A1 (es) 2022-01-28
MX2021009941A (es) 2021-12-10
CA3130406A1 (en) 2020-08-27
EP4349407A2 (en) 2024-04-10
MA55021A (fr) 2021-12-29
JP7598326B2 (ja) 2024-12-11
CN114555078A (zh) 2022-05-27
US20240307350A1 (en) 2024-09-19
ES2984438T3 (es) 2024-10-29
MA55021B1 (fr) 2024-05-31
JP2022521337A (ja) 2022-04-06
SMT202400154T1 (it) 2024-07-09
SI3927337T1 (sl) 2024-07-31
JP2025029035A (ja) 2025-03-05
PT4349407T (pt) 2025-06-04
PL3927337T3 (pl) 2024-07-29

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