PL442508A1 - Biofunkcjonalizowana powłoka organiczna, sposób jej otrzymywania oraz zastosowanie - Google Patents

Biofunkcjonalizowana powłoka organiczna, sposób jej otrzymywania oraz zastosowanie

Info

Publication number
PL442508A1
PL442508A1 PL442508A PL44250822A PL442508A1 PL 442508 A1 PL442508 A1 PL 442508A1 PL 442508 A PL442508 A PL 442508A PL 44250822 A PL44250822 A PL 44250822A PL 442508 A1 PL442508 A1 PL 442508A1
Authority
PL
Poland
Prior art keywords
biofunctionalized
application
organic coating
lysine
poly
Prior art date
Application number
PL442508A
Other languages
English (en)
Inventor
Paweł Taral
Małgorzata Skorupa
Katarzyna Krukiewicz
Original Assignee
Politechnika Śląska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Śląska filed Critical Politechnika Śląska
Priority to PL442508A priority Critical patent/PL442508A1/pl
Publication of PL442508A1 publication Critical patent/PL442508A1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Przedmiotem zgłoszenia jest biofunkcjonalizowana powłoka organiczna, która charakteryzuje się tym, że składa się od 0,5% do 10% masowych z warstwy zredukowanej soli diazoniowej o grubości od 10 nm do 200 nm pokrytej warstwą poli-L-lizyny o grubości 1 µm do 20 µm, co stanowi 90% do 99,5% masowych. Drugim przedmiotem zgłoszenia jest sposób wytwarzania biofunkcjonalizowanej powłoki organicznej, który polega na tym, że roztwór acetonitrylu zawierający 1 mM do 10 mM soli diazoniowej i 10 mM do 1000 mM elektrolitu poddaje się procesowi redukcji elektrochemicznej w zakresie potencjałów od -1,0 V do 0,5 V względem elektrody odniesienia, z szybkością skanowania od 0,01 V/s do 0,2 V/s w zakresie od 5 do 100 cykli woltamperometrycznych, po czym tak otrzymaną powłokę pokrywa się warstwą poli-L-lizyny o grubości od 1 µm do 20 µm zanurzając ją w wodnym roztworze poli-L-lizyny  o stężeniu 0,01 - 10% w/v w czasie od 10 min do 120 min. Zgłoszenie obejmuje także zastosowanie biofunkcjonalizowanej powłoki organicznej określonej powyżej jako pro-adhezyjna powłoka do modyfikacji powierzchni implantów stosowanych w inżynierii biomedycznej oraz weterynarii.
PL442508A 2022-10-12 2022-10-12 Biofunkcjonalizowana powłoka organiczna, sposób jej otrzymywania oraz zastosowanie PL442508A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL442508A PL442508A1 (pl) 2022-10-12 2022-10-12 Biofunkcjonalizowana powłoka organiczna, sposób jej otrzymywania oraz zastosowanie

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL442508A PL442508A1 (pl) 2022-10-12 2022-10-12 Biofunkcjonalizowana powłoka organiczna, sposób jej otrzymywania oraz zastosowanie

Publications (1)

Publication Number Publication Date
PL442508A1 true PL442508A1 (pl) 2024-04-15

Family

ID=90716785

Family Applications (1)

Application Number Title Priority Date Filing Date
PL442508A PL442508A1 (pl) 2022-10-12 2022-10-12 Biofunkcjonalizowana powłoka organiczna, sposób jej otrzymywania oraz zastosowanie

Country Status (1)

Country Link
PL (1) PL442508A1 (pl)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008090554A2 (en) * 2007-01-22 2008-07-31 Elutex Ltd. Modified conductive surfaces prepared by electrografting of diazonium salts
TW201338817A (zh) * 2012-03-22 2013-10-01 Nat Univ Chung Hsing 具有複合抗菌鍍層之生醫植入材及其製造方法
US9212430B1 (en) * 2007-10-31 2015-12-15 Sandia Corporation Method for the electro-addressable functionalization of electrode arrays
GB2592233A (en) * 2020-02-20 2021-08-25 Mirkhalaf Fakhradin Chemical modification of solids as backbones for controlled deposition of metal or bimetallic nanoparticles for tuning surface and antibacterial properties

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008090554A2 (en) * 2007-01-22 2008-07-31 Elutex Ltd. Modified conductive surfaces prepared by electrografting of diazonium salts
US9212430B1 (en) * 2007-10-31 2015-12-15 Sandia Corporation Method for the electro-addressable functionalization of electrode arrays
TW201338817A (zh) * 2012-03-22 2013-10-01 Nat Univ Chung Hsing 具有複合抗菌鍍層之生醫植入材及其製造方法
GB2592233A (en) * 2020-02-20 2021-08-25 Mirkhalaf Fakhradin Chemical modification of solids as backbones for controlled deposition of metal or bimetallic nanoparticles for tuning surface and antibacterial properties

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DAMIEN QUINTON ET AL., "FUNCTIONALIZATION OF TITANIUM SURFACES WITH A SIMPLE ELECTROCHEMICAL STRATEGY", SURFACE AND COATINGS TECHNOLOGY, VOLUME 206, ISSUES 8–9, 15 JANUARY 2012, PAGES 2302-2307 *
FLORIAN LEBON, "ORGANIC ELECTROGRAFTED THIN FILMS BASED NANO-DEVICES - CHAPTER II DIAZONIUM SALT ELECTROGRAFTING ON PATTERNED MICROMETER SIZED ELECTRODES , UNIVERSITÉ PARIS SACLAY (COMUE), 2019, P.29-49, *

Similar Documents

Publication Publication Date Title
Heien et al. Overoxidation of carbon-fiber microelectrodes enhances dopamine adsorption and increases sensitivity
KR101069310B1 (ko) 도파민, 아스코빅산 및 요산의 동시 검출이 가능한 전도성고분자 전극을 이용한 바이오센서 및 그 제조방법
Wang et al. Electrochemical response of dopamine at a penicillamine self-assembled gold electrode
Malinski et al. Diffusion of nitric oxide in the aorta wall monitored in situ by porphyrinic microsensors
De Long et al. Ionic interactions play a major role in determining the electrochemical behavior of self-assembling viologen monolayers
Casella et al. Study of the electrochemical deposition and properties of cobalt oxide species in citrate alkaline solutions
Shi et al. Determination of uric acid at electrochemically activated glassy carbon electrode
Saturno et al. Electroanalytical detection of Pb, Cd and traces of Cr at micro/nano-structured bismuth film electrodes
Cataldi et al. X-ray photoelectron spectroscopic investigation and electrochemistry of polynuclear indium (III) hexacyanoferrate films
Justin et al. Biomimetic hydrogels for biosensor implant biocompatibility: electrochemical characterization using micro-disc electrode arrays (MDEAs)
Stojko et al. Stripping voltammetric determination of mercury at modified solid electrodes: I. Development of the modified electrodes
KR101263837B1 (ko) 폴리도파민 박막의 전기화학적 코팅방법 및 폴리도파민 박막이 코팅된 신경전극
Perevezentseva et al. Electrochemical activity of methionine at graphite electrode modified with gold nanoparticles
Hrbáč et al. Nitric oxide sensor based on carbon fiber covered with nickel porphyrin layer deposited using optimized electropolymerization procedure
Hibbert et al. Mass changes and dissolution of platinum during electrical stimulation in artificial perilymph solution
Salazar et al. Microbiosensors for glucose based on Prussian Blue modified carbon fiber electrodes for in vivo monitoring in the central nervous system
PL442508A1 (pl) Biofunkcjonalizowana powłoka organiczna, sposób jej otrzymywania oraz zastosowanie
Jalali et al. Electrocatalytic oxidation of captopril using a carbon-paste electrode modified with copper-cobalt hexacyanoferrate
Ali et al. Determination of thiopentone sodium in aqueous and biological media by cathodic stripping voltammetry
Shahlaei et al. Simultaneous Determination of Tyrosine and Histidine by Differential Pulse Cathodic Stripping Voltammetry Using H‐point Standard Addition Method in Tap and Seawater
Martín et al. The use of fluorocarbons to mitigate the oxygen dependence of glucose microbiosensors for neuroscience applications
Mulla et al. Development of a voltammetric technique for monitoring brain dopamine metabolism: compensation for interference caused by DOPAC electrogenerated during homovanillic acid detection
DE4436001C2 (de) Biosensor mit auf einer Si¶3¶N¶4¶-Oberfläche fixiertem Enzym
CN111999357A (zh) 一种纳米银线阵列传感器的制备方法及其在抗坏血酸生物分子测定中的应用
PL447109A1 (pl) Sposób otrzymania pro-adhezyjnej powłoki organicznej