PL443656A1 - Aminowe pochodne dihydrodibenzo[b,f]oksepin i sposób ich otrzymywania - Google Patents
Aminowe pochodne dihydrodibenzo[b,f]oksepin i sposób ich otrzymywaniaInfo
- Publication number
- PL443656A1 PL443656A1 PL443656A PL44365623A PL443656A1 PL 443656 A1 PL443656 A1 PL 443656A1 PL 443656 A PL443656 A PL 443656A PL 44365623 A PL44365623 A PL 44365623A PL 443656 A1 PL443656 A1 PL 443656A1
- Authority
- PL
- Poland
- Prior art keywords
- dihydrodibenzo
- minutes
- oxepins
- boiling point
- production
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001412 amines Chemical class 0.000 title 1
- ATYBXHSAIOKLMG-UHFFFAOYSA-N oxepin Chemical compound O1C=CC=CC=C1 ATYBXHSAIOKLMG-UHFFFAOYSA-N 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000009835 boiling Methods 0.000 abstract 2
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine hydrate Chemical compound O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- -1 methoxynitrodibenzo[b,f]oxepine Chemical compound 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000002920 oxepines Chemical class 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Przedmiotem zgłoszenia są pochodne dihydrodibenzo[b,f]oksepiny o wzorze ogólnym 1 oraz sposób ich otrzymywania, charakteryzujący się tym, że metoksynitrodibenzo[b,f]oksepinę o wzorze 2 miesza się z katalizatorem w stosunku molowym 1:4 w rozpuszczalniku organicznym, następnie mieszaninę ogrzewa się w temperaturze wrzenia rozpuszczalnika przez 5 minut, po czym do mieszaniny reakcyjnej wkrapla się powoli monohydrat hydrazyny i miesza się przez kolejne 30 minut w temperaturze wrzenia, dalej mieszaninę poreakcyjną przesącza się i przemywa dwukrotnie etanolem, a uzyskany przesącz pozostawia się w temperaturze -15°C przez 24 godziny, po czym wydziela się z niego produkt końcowy za pomocą sączenia pod zmniejszonym ciśnieniem.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL443656A PL247188B1 (pl) | 2023-02-01 | 2023-02-01 | Aminowe pochodne dihydrodibenzo[b,f]oksepin i sposób ich otrzymywania |
| PCT/PL2024/050007 WO2024162861A1 (en) | 2023-02-01 | 2024-02-01 | AMINE DERIVATIVES OF DIHYDRODIBENZO[b,ƒ]OXEPINES AND METHOD OF PREPARATION THEREOF |
| EP24717814.8A EP4642771A1 (en) | 2023-02-01 | 2024-02-01 | AMINE DERIVATIVES OF DIHYDRODIBENZO[b,f]OXEPINES AND METHOD OF PREPARATION THEREOF |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL443656A PL247188B1 (pl) | 2023-02-01 | 2023-02-01 | Aminowe pochodne dihydrodibenzo[b,f]oksepin i sposób ich otrzymywania |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL443656A1 true PL443656A1 (pl) | 2024-08-05 |
| PL247188B1 PL247188B1 (pl) | 2025-05-26 |
Family
ID=90719961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL443656A PL247188B1 (pl) | 2023-02-01 | 2023-02-01 | Aminowe pochodne dihydrodibenzo[b,f]oksepin i sposób ich otrzymywania |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4642771A1 (pl) |
| PL (1) | PL247188B1 (pl) |
| WO (1) | WO2024162861A1 (pl) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL408698A1 (pl) * | 2014-06-30 | 2016-01-04 | Politechnika Warszawska | Sposób otrzymywania metoksylowych pochodnych dibenzo[b, f]oksepiny |
| PL424786A1 (pl) * | 2018-03-06 | 2019-09-09 | Politechnika Krakowska im. Tadeusza Kościuszki | System do wymuszania ruchów mas powietrza nad otwartymi obszarami |
| PL429386A1 (pl) * | 2019-03-25 | 2020-10-05 | Politechnika Warszawska | Sposób otrzymywania pochodnych dibenzo[b,f]oksepiny |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL247703B1 (pl) * | 2022-05-20 | 2025-08-25 | Politechnika Warszawska | Fluorowe pochodne metoksydibenzo[b,f]oksepiny oraz sposób ich otrzymywania |
-
2023
- 2023-02-01 PL PL443656A patent/PL247188B1/pl unknown
-
2024
- 2024-02-01 EP EP24717814.8A patent/EP4642771A1/en active Pending
- 2024-02-01 WO PCT/PL2024/050007 patent/WO2024162861A1/en not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL408698A1 (pl) * | 2014-06-30 | 2016-01-04 | Politechnika Warszawska | Sposób otrzymywania metoksylowych pochodnych dibenzo[b, f]oksepiny |
| PL424786A1 (pl) * | 2018-03-06 | 2019-09-09 | Politechnika Krakowska im. Tadeusza Kościuszki | System do wymuszania ruchów mas powietrza nad otwartymi obszarami |
| PL429386A1 (pl) * | 2019-03-25 | 2020-10-05 | Politechnika Warszawska | Sposób otrzymywania pochodnych dibenzo[b,f]oksepiny |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024162861A1 (en) | 2024-08-08 |
| PL247188B1 (pl) | 2025-05-26 |
| EP4642771A1 (en) | 2025-11-05 |
| WO2024162861A4 (en) | 2024-09-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Zhao et al. | Gold-catalyzed chemo-and diastereoselective C (sp 2)–H functionalization of enaminones for the synthesis of pyrrolo [3, 4-c]-quinolin-1-one derivatives | |
| US4324899A (en) | 2-Amino-5-cyanothiazoles and their preparation | |
| US3366619A (en) | Disazo pyrazolone pigments | |
| Kandeel et al. | Synthesis and in vitro antitumor activity of new benzothiazole and benzoxazole derivatives | |
| RU2707196C1 (ru) | 3-(2-Арил-2,4-дигидрокси-1(2-гидроксиэтил)-5-оксо-2,5-дигидро-1Н-пиррол-3-ил)хиноксалин-2(1Н)-оны, обладающие анальгетической активностью и способ их получения | |
| CN108658981A (zh) | 一种6-溴-4-甲氧基氢-吡唑[1,5-a]吡啶-3-甲腈的合成方法 | |
| CN103450091A (zh) | 一类咪唑类衍生物及其制备方法与用途 | |
| Savarino et al. | Aminophenyl‐X‐azolopyridines as precursors of heterocyclic azo dyes | |
| RU2379283C2 (ru) | Способ получения устойчивых солей арилдиазония | |
| CN116655528B (zh) | 一种氯化1-甲基烟酰铵的制备方法 | |
| Gromachevskaya et al. | Synthesis of 3, 4-Dihydroquinazolines in the Reaction of o-Aminophenyldiphenylcarbinol with Nitriles | |
| CN107382898B (zh) | 一种基于anpz含能母体结构的含能材料及其合成方法 | |
| RU2800861C1 (ru) | Способ получения 3-фенилдиазенил-1Н,1'Н-[2,3']бииндолов | |
| JP7683005B2 (ja) | Ｐｉ３ｋ阻害剤としての化合物の製造方法及びその製造のための中間体化合物 | |
| US2993043A (en) | Process for the manufacture of diimidazole derivatives | |
| US3364240A (en) | 4-aminobenzene-sulfonyl-aminoethyl-isothiuronium salts | |
| SU535903A3 (ru) | Способ получени замещенных бигуанидов | |
| CN106220611A (zh) | 2‑(1h‑吲哚‑3‑基)‑1h‑苯并咪唑衍生物的新制备方法 | |
| CN106831786A (zh) | 一种吡咯里嗪类化合物的合成方法 | |
| RU2486893C1 (ru) | Способ получения бис[3-метил(адамант-1-ил)]мочевин | |
| NO774407L (no) | Fremgangsmaate for fremstilling av imidazolderivater | |
| CN106317051B (zh) | 一种n-甲基依诺沙星(绕丹宁不饱和酮)酰胺类衍生物及其制备方法和应用 | |
| US2410938A (en) | Pyridine derivatives and process for the manufacture of same | |
| Yao et al. | Synthesis of Functionalized Thiophenes by Four‐component Reactions of 1, 3‐Thiazolidinedione, Aromatic Aldehydes, Cyanoacetamide and Cyclic Secondary Amines | |
| US2557721A (en) | 9, 10-dihydropteridines and process of preparing same |