PL444395A1 - 1-(1-aryloimidazolin-2-ylo)-3-aryloalkilo pochodne mocznika oraz sposób ich wytwarzania i ich zastosowanie - Google Patents

1-(1-aryloimidazolin-2-ylo)-3-aryloalkilo pochodne mocznika oraz sposób ich wytwarzania i ich zastosowanie

Info

Publication number
PL444395A1
PL444395A1 PL444395A PL44439523A PL444395A1 PL 444395 A1 PL444395 A1 PL 444395A1 PL 444395 A PL444395 A PL 444395A PL 44439523 A PL44439523 A PL 44439523A PL 444395 A1 PL444395 A1 PL 444395A1
Authority
PL
Poland
Prior art keywords
arylimidazolin
urea derivatives
production method
arylalkyl urea
arylalkyl
Prior art date
Application number
PL444395A
Other languages
English (en)
Other versions
PL248268B1 (pl
Inventor
Dariusz Matosiuk
Dominik Straszak
Sylwia Woźniak
Original Assignee
Uniwersytet Medyczny W Lublinie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Medyczny W Lublinie filed Critical Uniwersytet Medyczny W Lublinie
Priority to PL444395A priority Critical patent/PL248268B1/pl
Publication of PL444395A1 publication Critical patent/PL444395A1/pl
Publication of PL248268B1 publication Critical patent/PL248268B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem zgłoszenia są 1-(1-aryloimidazolin-2-ylo)-3-aryloalkilo pochodne mocznika oraz sposób ich wytwarzania i ich zastosowanie w leczeniu bólu neuropatycznego i przewlekłego.
PL444395A 2023-04-13 2023-04-13 1-(1-fenyloimidazolin-2-ylo)-3-aryloalkilo pochodne mocznika oraz sposób ich wytwarzania i ich zastosowanie PL248268B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL444395A PL248268B1 (pl) 2023-04-13 2023-04-13 1-(1-fenyloimidazolin-2-ylo)-3-aryloalkilo pochodne mocznika oraz sposób ich wytwarzania i ich zastosowanie

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL444395A PL248268B1 (pl) 2023-04-13 2023-04-13 1-(1-fenyloimidazolin-2-ylo)-3-aryloalkilo pochodne mocznika oraz sposób ich wytwarzania i ich zastosowanie

Publications (2)

Publication Number Publication Date
PL444395A1 true PL444395A1 (pl) 2024-10-14
PL248268B1 PL248268B1 (pl) 2025-11-17

Family

ID=93062646

Family Applications (1)

Application Number Title Priority Date Filing Date
PL444395A PL248268B1 (pl) 2023-04-13 2023-04-13 1-(1-fenyloimidazolin-2-ylo)-3-aryloalkilo pochodne mocznika oraz sposób ich wytwarzania i ich zastosowanie

Country Status (1)

Country Link
PL (1) PL248268B1 (pl)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8793082A (en) * 1981-09-03 1983-03-10 Hoechst A.G. Urea derivatives
WO1996010559A1 (en) * 1994-10-04 1996-04-11 Fujisawa Pharmaceutical Co., Ltd. Urea derivatives and their use as acat-inhibitors
WO2001036403A1 (en) * 1999-11-16 2001-05-25 Boehringer Ingelheim Pharmaceuticals, Inc. Urea derivatives as anti-inflammatory agents
EP1170288A2 (fr) * 2000-06-29 2002-01-09 Les Laboratoires Servier Dérivés de diphenylurée et leur utilisation en tant qu'antagonistes alpha2/5-HT2c

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8793082A (en) * 1981-09-03 1983-03-10 Hoechst A.G. Urea derivatives
WO1996010559A1 (en) * 1994-10-04 1996-04-11 Fujisawa Pharmaceutical Co., Ltd. Urea derivatives and their use as acat-inhibitors
WO2001036403A1 (en) * 1999-11-16 2001-05-25 Boehringer Ingelheim Pharmaceuticals, Inc. Urea derivatives as anti-inflammatory agents
EP1170288A2 (fr) * 2000-06-29 2002-01-09 Les Laboratoires Servier Dérivés de diphenylurée et leur utilisation en tant qu'antagonistes alpha2/5-HT2c

Also Published As

Publication number Publication date
PL248268B1 (pl) 2025-11-17

Similar Documents

Publication Publication Date Title
MY206999A (en) Treatment of hidradenitis suppurativa using jak inhibitors
WO2022069748A3 (en) Wearable device for decreasing the respiratory effort of a sleeping subject
IL287728A (en) Combination of pd-1 inhibitors and lag-3 inhibitors for enhanced efficacy in treating cancer
WO2011127188A3 (en) Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
MX2023014435A (es) Inhibidores de la tirosina quinasa de bruton y métodos de su uso.
EP3975703A4 (en) PENETRATING TOPICAL PAIN RELIEF COMPOSITIONS AND METHODS OF USE
MA28739B1 (fr) Derives de n-(1-(1-benzyl-4-phenyl-1h-imidazol-2-yl)-2,2-dymethylpropyl) benzamide et composes associes comme inhibiteurs de la proteine kinesine fuseau (ksp) pour le traitement du cancer
ATE404202T1 (de) Die verwendung von potenten, selektiven und nontoxischen c-kithemmern zur behandlung von interstitieller blasenentzündung
EP4467538A4 (en) BENZIMIDAZOLE OR AZABENZIMIDAZOLE COMPOUND, ITS PREPARATION PROCESS AND ITS USE
MX2024005107A (es) Nuevo uso de compuesto de quinazolinona para el tratamiento de cancer.
MX2023006542A (es) Inhibidores de la vía cinasa jano 1 (jak1) para el tratamiento del vitiligo.
BR112022018115A2 (pt) Inibidor de cxcr4 para o tratamento de síndrome de desconforto respiratório agudo e infecções virais
MX2024014121A (es) Metodos y composiciones para el tratamiento del exceso de glucocorticoides
PL444395A1 (pl) 1-(1-aryloimidazolin-2-ylo)-3-aryloalkilo pochodne mocznika oraz sposób ich wytwarzania i ich zastosowanie
PE20200600A1 (es) Composiciones y metodos para promover el crecimiento del cabello con inhibidores de mpc
WO2022119858A8 (en) Compounds for the treatment of sars
MX2023003583A (es) Forma cristalina del compuesto de piridinilfenilo y metodo de preparacion del mismo.
IL320848A (en) RIPK2 inhibitors and their medical uses
MX2025012183A (es) Formas cristalinas de un inhibidor de ras
EP4375270A4 (en) SUPRAMOLECULAR AMINO ACID OR SALT THEREOF, ITS PREPARATION PROCESS AND ITS USE
ATE549018T1 (de) Verwendung eines vanilloidrezeptoragonisten zusammen mit einem glycosaminoglycan oder proteoglycan für die herstellung eines mittels zur behandlung von gelenkschmerzen und verfahren zur applikation dieses mittels
MX2021002590A (es) Metodos de uso de un compuesto de fenoxipropilamina para tratar el dolor.
IL307237A (en) Intravascular catheter and method of use
MX2024015040A (es) Fitusiran para el tratamiento de la hemofilia a y b en pacientes pediatricos
MX2023015147A (es) Inhibidores de la tirosina quinasa de bruton y métodos de su uso.