PL445849A1 - Muteiny ludzkiego czynnika wzrostu fibroblastów 1 (FGF-1), ich dimery i zastosowania - Google Patents

Muteiny ludzkiego czynnika wzrostu fibroblastów 1 (FGF-1), ich dimery i zastosowania

Info

Publication number
PL445849A1
PL445849A1 PL445849A PL44584921A PL445849A1 PL 445849 A1 PL445849 A1 PL 445849A1 PL 445849 A PL445849 A PL 445849A PL 44584921 A PL44584921 A PL 44584921A PL 445849 A1 PL445849 A1 PL 445849A1
Authority
PL
Poland
Prior art keywords
muteins
fgf
dimers
growth factor
fibroblast growth
Prior art date
Application number
PL445849A
Other languages
English (en)
Inventor
Jacek Józef OTLEWSKI
Małgorzata Urszula ZAKRZEWSKA
Daniel Rafał KROWARSCH
Aleksandra Czyrek
Michał Mieczysław JANISZEWSKI
Jerzy Szczepan Pieczykolan
Ewa DRZAZGA
Katarzyna BAZYDŁO-GUZENDA
Paweł BUDA
Maciej Wieczorek
Original Assignee
Celon Pharma Spółka Akcyjna
Uniwersytet Wrocławski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celon Pharma Spółka Akcyjna, Uniwersytet Wrocławski filed Critical Celon Pharma Spółka Akcyjna
Priority to PL445849A priority Critical patent/PL445849A1/pl
Publication of PL445849A1 publication Critical patent/PL445849A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
PL445849A 2021-05-26 2021-05-26 Muteiny ludzkiego czynnika wzrostu fibroblastów 1 (FGF-1), ich dimery i zastosowania PL445849A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL445849A PL445849A1 (pl) 2021-05-26 2021-05-26 Muteiny ludzkiego czynnika wzrostu fibroblastów 1 (FGF-1), ich dimery i zastosowania

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL445849A PL445849A1 (pl) 2021-05-26 2021-05-26 Muteiny ludzkiego czynnika wzrostu fibroblastów 1 (FGF-1), ich dimery i zastosowania

Publications (1)

Publication Number Publication Date
PL445849A1 true PL445849A1 (pl) 2024-12-02

Family

ID=93707008

Family Applications (1)

Application Number Title Priority Date Filing Date
PL445849A PL445849A1 (pl) 2021-05-26 2021-05-26 Muteiny ludzkiego czynnika wzrostu fibroblastów 1 (FGF-1), ich dimery i zastosowania

Country Status (1)

Country Link
PL (1) PL445849A1 (pl)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016172156A2 (en) * 2015-04-20 2016-10-27 Salk Institute For Biological Studies Fibroblast growth factor (fgf) 1 mutants and methods of use to reduce blood glucose
WO2017075260A1 (en) * 2015-10-30 2017-05-04 Salk Institute For Biological Studies Treatment of steroid-induced hyperglycemia with fibroblast growth factor (fgf) 1 analogs
WO2018026713A1 (en) * 2016-08-01 2018-02-08 Salk Institute For Biological Studies Fibroblast growth factor (fgf) 1 proteins with glucose lowering ability and reduced mitogenicity
WO2018112200A1 (en) * 2016-12-15 2018-06-21 Salk Institute For Biological Studies Use of fibroblast growth factor 1 (fgf1)-vagus nerve targeting chimeric proteins to treat hyperglycemia

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016172156A2 (en) * 2015-04-20 2016-10-27 Salk Institute For Biological Studies Fibroblast growth factor (fgf) 1 mutants and methods of use to reduce blood glucose
WO2017075260A1 (en) * 2015-10-30 2017-05-04 Salk Institute For Biological Studies Treatment of steroid-induced hyperglycemia with fibroblast growth factor (fgf) 1 analogs
WO2018026713A1 (en) * 2016-08-01 2018-02-08 Salk Institute For Biological Studies Fibroblast growth factor (fgf) 1 proteins with glucose lowering ability and reduced mitogenicity
WO2018112200A1 (en) * 2016-12-15 2018-06-21 Salk Institute For Biological Studies Use of fibroblast growth factor 1 (fgf1)-vagus nerve targeting chimeric proteins to treat hyperglycemia

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