PL448149A1 - Peptyd o działaniu osteogennym oraz jego zastosowanie - Google Patents

Peptyd o działaniu osteogennym oraz jego zastosowanie

Info

Publication number
PL448149A1
PL448149A1 PL448149A PL44814924A PL448149A1 PL 448149 A1 PL448149 A1 PL 448149A1 PL 448149 A PL448149 A PL 448149A PL 44814924 A PL44814924 A PL 44814924A PL 448149 A1 PL448149 A1 PL 448149A1
Authority
PL
Poland
Prior art keywords
lys
peptide
arg
application
phe
Prior art date
Application number
PL448149A
Other languages
English (en)
Inventor
Michał PIKUŁA
Agata Tymińska
Aneta Skoniecka
Małgorzata Zawrzykraj
Jacek ZIELIŃSKI
Sylwia RODZIEWICZ-MOTOWIDŁO
Natalia Karska
Agnieszka Kubiś
Piotr Skowron
Original Assignee
Uniwersytet Gdański
Gdański Uniwersytet Medyczny
Politechnika Gdańska
Innovabion Spółka Z Ograniczoną Odpowiedzialnością
Nex.D Spółka Z Ograniczoną Odpowiedzialnością
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Gdański, Gdański Uniwersytet Medyczny, Politechnika Gdańska, Innovabion Spółka Z Ograniczoną Odpowiedzialnością, Nex.D Spółka Z Ograniczoną Odpowiedzialnością filed Critical Uniwersytet Gdański
Priority to PL448149A priority Critical patent/PL448149A1/pl
Publication of PL448149A1 publication Critical patent/PL448149A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Przedmiotem zgłoszenia jest peptyd oznaczony jako UG27 0 sekwencji aminokwasowej Phe-Phe-Gly-Val-Asn-Pro-Lys-Tyr-Lys-Gln-Lys-Arg-Arg - (FFGVNPKYKQKRR) stanowiący środek o działaniu stymulującym osteogenezę komórek mezenchymanych pozyskiwanych z tkanki tłuszczowej. Zgłoszenie obejmuje również zastosowanie medyczne peptydu UG27 jako leku, który może pobudzać proces osteogenezy w komórkach stromalnych u ludzi w celu leczenia ubytków kostnych.
PL448149A 2024-03-29 2024-03-29 Peptyd o działaniu osteogennym oraz jego zastosowanie PL448149A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL448149A PL448149A1 (pl) 2024-03-29 2024-03-29 Peptyd o działaniu osteogennym oraz jego zastosowanie

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL448149A PL448149A1 (pl) 2024-03-29 2024-03-29 Peptyd o działaniu osteogennym oraz jego zastosowanie

Publications (1)

Publication Number Publication Date
PL448149A1 true PL448149A1 (pl) 2025-10-06

Family

ID=97229885

Family Applications (1)

Application Number Title Priority Date Filing Date
PL448149A PL448149A1 (pl) 2024-03-29 2024-03-29 Peptyd o działaniu osteogennym oraz jego zastosowanie

Country Status (1)

Country Link
PL (1) PL448149A1 (pl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103880928A (zh) * 2014-03-28 2014-06-25 甘少磊 一种诱导成骨短肽及其制备方法和用途
EP3505529A1 (en) * 2016-08-26 2019-07-03 Sewon Biotechnology Inc. Peptide for promoting osteoanagenesis or osteogenesis and use of same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103880928A (zh) * 2014-03-28 2014-06-25 甘少磊 一种诱导成骨短肽及其制备方法和用途
EP3505529A1 (en) * 2016-08-26 2019-07-03 Sewon Biotechnology Inc. Peptide for promoting osteoanagenesis or osteogenesis and use of same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEN, Y., LIU, X., LIU, R., GONG, Y., WANG, M., HUANG, Q., FENG, Q., YU, B.: "Theranostics 2017, 7, 1072-1087.", ZERO-ORDER CONTROLLED RELEASE OF BMP2-DERIVED PEPTIDE P24 FROM THE CHITOSAN SCAFFOLD BY CHEMICAL GRAFTING MODIFICATION TECHNIQUE FOR PROMOTION OF OSTEOGENESIS IN VITRO AND ENHANCEMENT OF BONE REPAIR IN VIVO. *
LEE, D., PARK, K.S., YOON, G.J., LEE, H.J., LEE, J.Y., PARK, Y.S., PARK, J.C., LEE, G., CHUNG, C.P., PARK, Y.J.: "J Biomed Mater Res A 2019, 107, 2392-2402.", IDENTIFICATION OF CELL-PENETRATING OSTEOGENIC PEPTIDE FROM COPINE-7 PROTEIN AND ITS DELIVERY SYSTEM FOR ENHANCED BONE FORMATION. *

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