PL449412A1 - Crystalline form of the poly-[bis(6-bromo-imidazo[1,2-a]pyridine)manganese(II)-(μ2-quinoline-2-carboxylato-κ2N,O:κO')-bis(quinoline-2-carboxylato-κ2N,O)manganese(II)] complex, method for preparation of the same and use thereof - Google Patents

Crystalline form of the poly-[bis(6-bromo-imidazo[1,2-a]pyridine)manganese(II)-(μ2-quinoline-2-carboxylato-κ2N,O:κO')-bis(quinoline-2-carboxylato-κ2N,O)manganese(II)] complex, method for preparation of the same and use thereof

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Publication number
PL449412A1
PL449412A1 PL449412A PL44941224A PL449412A1 PL 449412 A1 PL449412 A1 PL 449412A1 PL 449412 A PL449412 A PL 449412A PL 44941224 A PL44941224 A PL 44941224A PL 449412 A1 PL449412 A1 PL 449412A1
Authority
PL
Poland
Prior art keywords
carboxylato
quinoline
manganese
bis
imidazo
Prior art date
Application number
PL449412A
Other languages
Polish (pl)
Inventor
Tomasz Mazur
Magdalena Malik
Olga Wesołowska
Kamila Środa-Pomianek
Original Assignee
Politechnika Wrocławska
Uniwersytet Medyczny Im. Piastów Śląskich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Wrocławska, Uniwersytet Medyczny Im. Piastów Śląskich filed Critical Politechnika Wrocławska
Priority to PL449412A priority Critical patent/PL449412A1/en
Publication of PL449412A1 publication Critical patent/PL449412A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Przedmiotem zgłoszenia jest krystaliczna forma kompleksu poli-[bis(6-bromo-imidazo[1,2-a]pirydyna)mangan(II)-(µ2-chinolina-2-karboksylato-ĸ2N,O:ĸO') -bis(chinolina-2-karboksylato-ĸ2N,O)mangan(II)] oraz sposób jego otrzymywania. Zgłoszenie dotyczy również zastosowania krystalicznej formy kompleksu poli-[bis(6-bromo-imidazo[1,2-a]pirydyna)mangan(II)-(µ2-chinolina-2-karboksylato-ĸ2N,O:ĸO')-bis(chinolina-2-karboksylato-ĸ2N,O)mangan(II)] jako leku o działaniu przeciwnowotworowym.The subject of the application is a crystalline form of the complex poly-[bis(6-bromo-imidazo[1,2-a]pyridine)manganese(II)-(µ2-quinoline-2-carboxylato-ĸ2N,O:ĸO')-bis(quinoline-2-carboxylato-ĸ2N,O)manganese(II)] and a method for obtaining it. The application also relates to the use of the crystalline form of the complex poly-[bis(6-bromo-imidazo[1,2-a]pyridine)manganese(II)-(µ2-quinoline-2-carboxylato-ĸ2N,O:ĸO')-bis(quinoline-2-carboxylato-ĸ2N,O)manganese(II)] as an anticancer drug.

PL449412A 2024-07-30 2024-07-30 Crystalline form of the poly-[bis(6-bromo-imidazo[1,2-a]pyridine)manganese(II)-(μ2-quinoline-2-carboxylato-κ2N,O:κO')-bis(quinoline-2-carboxylato-κ2N,O)manganese(II)] complex, method for preparation of the same and use thereof PL449412A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL449412A PL449412A1 (en) 2024-07-30 2024-07-30 Crystalline form of the poly-[bis(6-bromo-imidazo[1,2-a]pyridine)manganese(II)-(μ2-quinoline-2-carboxylato-κ2N,O:κO')-bis(quinoline-2-carboxylato-κ2N,O)manganese(II)] complex, method for preparation of the same and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL449412A PL449412A1 (en) 2024-07-30 2024-07-30 Crystalline form of the poly-[bis(6-bromo-imidazo[1,2-a]pyridine)manganese(II)-(μ2-quinoline-2-carboxylato-κ2N,O:κO')-bis(quinoline-2-carboxylato-κ2N,O)manganese(II)] complex, method for preparation of the same and use thereof

Publications (1)

Publication Number Publication Date
PL449412A1 true PL449412A1 (en) 2026-02-02

Family

ID=98605017

Family Applications (1)

Application Number Title Priority Date Filing Date
PL449412A PL449412A1 (en) 2024-07-30 2024-07-30 Crystalline form of the poly-[bis(6-bromo-imidazo[1,2-a]pyridine)manganese(II)-(μ2-quinoline-2-carboxylato-κ2N,O:κO')-bis(quinoline-2-carboxylato-κ2N,O)manganese(II)] complex, method for preparation of the same and use thereof

Country Status (1)

Country Link
PL (1) PL449412A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096264A (en) * 1975-12-09 1978-06-20 Merck & Co., Inc. Certain substituted imidazo [1,2-a] pyridines
CA1036490A (en) * 1973-08-06 1978-08-15 Montedison S.P.A. Derivatives of quinoline-8-carboxylic acid having pesticidal action

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1036490A (en) * 1973-08-06 1978-08-15 Montedison S.P.A. Derivatives of quinoline-8-carboxylic acid having pesticidal action
US4096264A (en) * 1975-12-09 1978-06-20 Merck & Co., Inc. Certain substituted imidazo [1,2-a] pyridines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEEP A, BHATIA RK, KAUR R, KUMAR S, JAIN UK, SINGH H, BATRA S, KAUSHIK D, DEB PK: "Curr Top Med Chem. 2017;17(2):238-250", "IMIDAZO[1,2-A]PYRIDINE SCAFFOLD AS PROSPECTIVE THERAPEUTIC AGENTS" *
LANGNER E, JELENIEWICZ W, TURSKI WA, PLECH T.: "Pharmacol Rep. 2019 Apr;71(2):189-193", "QUINALDIC ACID INDUCES CHANGES IN THE EXPRESSION OF P53 TUMOR SUPPRESSOR BOTH ON PROTEIN AND GENE LEVEL IN COLON, CANCER LS180 CELLS" *

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