PL449636A1 - Hypoxia generation cartridge for microfluidic flow systems - Google Patents

Hypoxia generation cartridge for microfluidic flow systems

Info

Publication number
PL449636A1
PL449636A1 PL449636A PL44963624A PL449636A1 PL 449636 A1 PL449636 A1 PL 449636A1 PL 449636 A PL449636 A PL 449636A PL 44963624 A PL44963624 A PL 44963624A PL 449636 A1 PL449636 A1 PL 449636A1
Authority
PL
Poland
Prior art keywords
hypoxia
outlet
flow systems
microfluidic flow
generation cartridge
Prior art date
Application number
PL449636A
Other languages
Polish (pl)
Inventor
Dominik Kołodziejek
Aleksandra Szlachetka
Elżbieta Jastrzębska
Original Assignee
Politechnika Warszawska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Warszawska filed Critical Politechnika Warszawska
Priority to PL449636A priority Critical patent/PL449636A1/en
Publication of PL449636A1 publication Critical patent/PL449636A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B1/00—Devices without movable or flexible elements, e.g. microcapillary devices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/048—Function or devices integrated in the closure enabling gas exchange, e.g. vents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Computer Hardware Design (AREA)
  • Medicinal Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)

Abstract

Przedmiotem zgłoszenia jest kartridż do generowania hipoksji w mikrosystemach przepływowych, charakteryzujący się tym, że zawiera trzy połączone ze sobą rozłącznie, zasadniczo prostopadłościenne płytki: dolną (1), środkową (2) oraz górną (3), przy czym płytka dolna (1) zawiera strefy hipoksji (4) i normoksji (5) na umieszczenie w nich płytek mikrosystemu przepływowego, do których doprowadzany jest gaz poprzez kanały wlotowy (6) i wylotowy (7) gazu oraz porty wlotowy (9) i wylotowy (10) gazu, przy czym płytka środkowa (2) zawiera wcięcia na port wlotowy (13) i wylotowy (12) mikrosystemu przepływowego oraz otwór na płytkę górną (3), która posiada w centralnej części płaską powierzchnię na umieszczenie elementu grzewczego (22).The subject of the application is a cartridge for generating hypoxia in microfluidic systems, characterized in that it comprises three releasably connected, substantially cuboidal plates: a lower (1), a middle (2) and an upper (3), wherein the lower plate (1) comprises hypoxia (4) and normoxia (5) zones for placing microfluidic system plates therein, to which gas is supplied via gas inlet (6) and outlet (7) channels and gas inlet (9) and outlet (10) ports, wherein the middle plate (2) comprises notches for the inlet (13) and outlet (12) ports of the microfluidic system and an opening for the upper plate (3), which has a flat surface in its central part for placing a heating element (22).

PL449636A 2024-08-30 2024-08-30 Hypoxia generation cartridge for microfluidic flow systems PL449636A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL449636A PL449636A1 (en) 2024-08-30 2024-08-30 Hypoxia generation cartridge for microfluidic flow systems

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL449636A PL449636A1 (en) 2024-08-30 2024-08-30 Hypoxia generation cartridge for microfluidic flow systems

Publications (1)

Publication Number Publication Date
PL449636A1 true PL449636A1 (en) 2025-04-28

Family

ID=95554639

Family Applications (1)

Application Number Title Priority Date Filing Date
PL449636A PL449636A1 (en) 2024-08-30 2024-08-30 Hypoxia generation cartridge for microfluidic flow systems

Country Status (1)

Country Link
PL (1) PL449636A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090275072A1 (en) * 2003-09-16 2009-11-05 Incube Laboratories, Inc In Vitro bio-reactor circuit
CA2815085A1 (en) * 2010-10-22 2012-04-26 T2 Biosystems, Inc. Nmr systems and methods for the rapid detection of analytes
CN106520553A (en) * 2017-01-06 2017-03-22 昆明理工大学 Cell culture room

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090275072A1 (en) * 2003-09-16 2009-11-05 Incube Laboratories, Inc In Vitro bio-reactor circuit
CA2815085A1 (en) * 2010-10-22 2012-04-26 T2 Biosystems, Inc. Nmr systems and methods for the rapid detection of analytes
CN106520553A (en) * 2017-01-06 2017-03-22 昆明理工大学 Cell culture room

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