PL450544A1 - Czwartorzędowe sole amoniowe z kationem 3-karbamoilo-1-alkilopirydyniowym i anionem (S)-migdalanowym, sposób ich otrzymywania oraz zastosowanie jako substancje o aktywności przeciwbakteryjnej - Google Patents

Czwartorzędowe sole amoniowe z kationem 3-karbamoilo-1-alkilopirydyniowym i anionem (S)-migdalanowym, sposób ich otrzymywania oraz zastosowanie jako substancje o aktywności przeciwbakteryjnej

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Publication number
PL450544A1
PL450544A1 PL450544A PL45054424A PL450544A1 PL 450544 A1 PL450544 A1 PL 450544A1 PL 450544 A PL450544 A PL 450544A PL 45054424 A PL45054424 A PL 45054424A PL 450544 A1 PL450544 A1 PL 450544A1
Authority
PL
Poland
Prior art keywords
carbamoyl
quaternary ammonium
ammonium salts
preparation
antibacterial agents
Prior art date
Application number
PL450544A
Other languages
English (en)
Inventor
Michał NIEMCZAK
Adriana Olejniczak
Original Assignee
Politechnika Poznańska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Poznańska filed Critical Politechnika Poznańska
Priority to PL450544A priority Critical patent/PL450544A1/pl
Publication of PL450544A1 publication Critical patent/PL450544A1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C07C59/50—Mandelic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem zgłoszenia są czwartorzędowe sole amoniowe z kationem 3-karbamoilo-1-alkilopirydyniowym i anionem (S)-migdalanowym, o wzorze ogólnym 1, w którym R oznacza nierozgałęziony łańcuch alkilowy o długości od 2 do 12 atomów węgla, sposób ich otrzymywania i zastosowanie jako substancje o aktywności przeciwbakteryjnej względem bakterii wywołujących trądzik.
PL450544A 2024-12-11 2024-12-11 Czwartorzędowe sole amoniowe z kationem 3-karbamoilo-1-alkilopirydyniowym i anionem (S)-migdalanowym, sposób ich otrzymywania oraz zastosowanie jako substancje o aktywności przeciwbakteryjnej PL450544A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL450544A PL450544A1 (pl) 2024-12-11 2024-12-11 Czwartorzędowe sole amoniowe z kationem 3-karbamoilo-1-alkilopirydyniowym i anionem (S)-migdalanowym, sposób ich otrzymywania oraz zastosowanie jako substancje o aktywności przeciwbakteryjnej

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL450544A PL450544A1 (pl) 2024-12-11 2024-12-11 Czwartorzędowe sole amoniowe z kationem 3-karbamoilo-1-alkilopirydyniowym i anionem (S)-migdalanowym, sposób ich otrzymywania oraz zastosowanie jako substancje o aktywności przeciwbakteryjnej

Publications (1)

Publication Number Publication Date
PL450544A1 true PL450544A1 (pl) 2026-06-15

Family

ID=100212563

Family Applications (1)

Application Number Title Priority Date Filing Date
PL450544A PL450544A1 (pl) 2024-12-11 2024-12-11 Czwartorzędowe sole amoniowe z kationem 3-karbamoilo-1-alkilopirydyniowym i anionem (S)-migdalanowym, sposób ich otrzymywania oraz zastosowanie jako substancje o aktywności przeciwbakteryjnej

Country Status (1)

Country Link
PL (1) PL450544A1 (pl)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005067927A2 (en) * 2004-01-12 2005-07-28 Pharmena Sp Z O.O. The use of quaternary pyridinium salts as vasoprotective agents
PL211459B1 (pl) * 1999-01-07 2012-05-31 Pharmena Społka Akcyjna Zastosowanie czwartorzędowych soli pirydyniowych oraz preparat farmaceutyczny zawierający czwartorzędowe sole pirydyniowe
PL213547B1 (pl) * 2009-06-05 2013-03-29 Inst Chemii Przemyslowej Im Prof Ignacego Moscickiego Nowe amoniowe ciecze jonowe, sposób ich otrzymywania oraz ich zastosowanie

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL211459B1 (pl) * 1999-01-07 2012-05-31 Pharmena Społka Akcyjna Zastosowanie czwartorzędowych soli pirydyniowych oraz preparat farmaceutyczny zawierający czwartorzędowe sole pirydyniowe
WO2005067927A2 (en) * 2004-01-12 2005-07-28 Pharmena Sp Z O.O. The use of quaternary pyridinium salts as vasoprotective agents
PL213547B1 (pl) * 2009-06-05 2013-03-29 Inst Chemii Przemyslowej Im Prof Ignacego Moscickiego Nowe amoniowe ciecze jonowe, sposób ich otrzymywania oraz ich zastosowanie