PL452423A1 - Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających kation 3-karbamoilo-1-alkilopirydyniowy i anion 4-aminobenzoesanowy z użyciem albuminy jaja kurzego - Google Patents

Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających kation 3-karbamoilo-1-alkilopirydyniowy i anion 4-aminobenzoesanowy z użyciem albuminy jaja kurzego

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Publication number
PL452423A1
PL452423A1 PL452423A PL45242325A PL452423A1 PL 452423 A1 PL452423 A1 PL 452423A1 PL 452423 A PL452423 A PL 452423A PL 45242325 A PL45242325 A PL 45242325A PL 452423 A1 PL452423 A1 PL 452423A1
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Poland
Prior art keywords
aminobenzoate
ovalbumin
carbamoyl
anion
determining
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PL452423A
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English (en)
Inventor
Adriana Olejniczak
Michał NIEMCZAK
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Politechnika Poznańska
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Application filed by Politechnika Poznańska filed Critical Politechnika Poznańska
Priority to PL452423A priority Critical patent/PL452423A1/pl
Publication of PL452423A1 publication Critical patent/PL452423A1/pl

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/77—Ovalbumin

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Przedmiotem zgłoszenia jest sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających kation 3-karbamoilo-1-alkilopirydyniowy i anion 4-aminobenzoesanowy, o wzorze ogólnym 1, gdzie R oznacza podstawnik alkilowy zawierający od 6 do 12 atomów węgla, z użyciem albuminy jaja kurzego.
PL452423A 2025-06-20 2025-06-20 Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających kation 3-karbamoilo-1-alkilopirydyniowy i anion 4-aminobenzoesanowy z użyciem albuminy jaja kurzego PL452423A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL452423A PL452423A1 (pl) 2025-06-20 2025-06-20 Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających kation 3-karbamoilo-1-alkilopirydyniowy i anion 4-aminobenzoesanowy z użyciem albuminy jaja kurzego

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL452423A PL452423A1 (pl) 2025-06-20 2025-06-20 Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających kation 3-karbamoilo-1-alkilopirydyniowy i anion 4-aminobenzoesanowy z użyciem albuminy jaja kurzego

Publications (1)

Publication Number Publication Date
PL452423A1 true PL452423A1 (pl) 2026-08-03

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL452423A PL452423A1 (pl) 2025-06-20 2025-06-20 Sposób określania właściwości przeciwzapalnych czwartorzędowych soli amoniowych zawierających kation 3-karbamoilo-1-alkilopirydyniowy i anion 4-aminobenzoesanowy z użyciem albuminy jaja kurzego

Country Status (1)

Country Link
PL (1) PL452423A1 (pl)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005067927A2 (en) * 2004-01-12 2005-07-28 Pharmena Sp Z O.O. The use of quaternary pyridinium salts as vasoprotective agents
PL211459B1 (pl) * 1999-01-07 2012-05-31 Pharmena Społka Akcyjna Zastosowanie czwartorzędowych soli pirydyniowych oraz preparat farmaceutyczny zawierający czwartorzędowe sole pirydyniowe
RU2497804C1 (ru) * 2012-05-02 2013-11-10 Федеральное государственное бюджетное учреждение науки институт химии растворов им. Г.А. Крестова Российской академии наук Сокристаллическая форма 2-гидроксибензамида с 4-аминобензойной кислотой

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL211459B1 (pl) * 1999-01-07 2012-05-31 Pharmena Społka Akcyjna Zastosowanie czwartorzędowych soli pirydyniowych oraz preparat farmaceutyczny zawierający czwartorzędowe sole pirydyniowe
WO2005067927A2 (en) * 2004-01-12 2005-07-28 Pharmena Sp Z O.O. The use of quaternary pyridinium salts as vasoprotective agents
RU2497804C1 (ru) * 2012-05-02 2013-11-10 Федеральное государственное бюджетное учреждение науки институт химии растворов им. Г.А. Крестова Российской академии наук Сокристаллическая форма 2-гидроксибензамида с 4-аминобензойной кислотой

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RAD E.Y. I IN.,: "Eur J Nutr. 2024; 63(6): 2011-2024.", THE EFFECT OF NIACIN ON INFLAMMATORY MARKERS AND ADIPOKINES: A SYSTEMATIC REVIEW AND META-ANALYSIS OF INTERVENTIONAL STUDIES, DOI: 10.1007/s00394-024-03425-8. *