PL9461B1 - A method of making lozenges and similar dosed medicinal products. - Google Patents
A method of making lozenges and similar dosed medicinal products. Download PDFInfo
- Publication number
- PL9461B1 PL9461B1 PL9461A PL946127A PL9461B1 PL 9461 B1 PL9461 B1 PL 9461B1 PL 9461 A PL9461 A PL 9461A PL 946127 A PL946127 A PL 946127A PL 9461 B1 PL9461 B1 PL 9461B1
- Authority
- PL
- Poland
- Prior art keywords
- similar
- lozenges
- medicinal products
- dosed medicinal
- making lozenges
- Prior art date
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- 239000007937 lozenge Substances 0.000 title claims description 6
- 238000004519 manufacturing process Methods 0.000 title claims 2
- 229940126601 medicinal product Drugs 0.000 title description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 6
- 239000004202 carbamide Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 1
- 239000010931 gold Substances 0.000 claims 1
- 229910052737 gold Inorganic materials 0.000 claims 1
- -1 stamens Substances 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Chemical compound OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- XGEGHDBEHXKFPX-UHFFFAOYSA-N N-methyl urea Chemical compound CNC(N)=O XGEGHDBEHXKFPX-UHFFFAOYSA-N 0.000 description 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 2
- YAPQBXQYLJRXSA-UHFFFAOYSA-N theobromine Chemical compound CN1C(=O)NC(=O)C2=C1N=CN2C YAPQBXQYLJRXSA-UHFFFAOYSA-N 0.000 description 2
- FTOAOBMCPZCFFF-UHFFFAOYSA-N 5,5-diethylbarbituric acid Chemical compound CCC1(CC)C(=O)NC(=O)NC1=O FTOAOBMCPZCFFF-UHFFFAOYSA-N 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- ABBQHOQBGMUPJH-UHFFFAOYSA-M Sodium salicylate Chemical compound [Na+].OC1=CC=CC=C1C([O-])=O ABBQHOQBGMUPJH-UHFFFAOYSA-M 0.000 description 1
- 229960002319 barbital Drugs 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 229960004025 sodium salicylate Drugs 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960004559 theobromine Drugs 0.000 description 1
Description
Spostrzezono, ze do wyrobu pastylek i podobnych wytworów leczniczych mozna stosowac mocznik i jego pochodne rozpu¬ szczalne w wodzie. Mocznik nie jest tru¬ cizna i smak jego nie jest nieprzyjemny.Ma on ponadto te zalete, ze nie jest higro- skopijny, wskutek czego odpada po¬ trzeba stosowania domieszek wiazacych wode.Stosowanie mocznika nie wyklucza jednoczesnego dodawania zwykle stosowa¬ nych przy wytlaczaniu pastylek rozpu¬ szczalnych w wodzie srodków, jako to cu¬ kru, cukru mlecznego, dwuweglanu sodo¬ wego i t. d.Przyklad L 2 czesci wagowe mocznika miesza sie dokladnie z 1 czescia wagowa sublimatu, poczem z mieszaniny tej wyra¬ bia sie w sposób zwykly pastylki 1,5 gra¬ mowe.Przyklad IL Azotan srebra i mocznik w równych ilosciach miesza sie dokladnie i z mieszaniny tej wytlacza preciki.Przyklad III. Mieszanine salicylanu so¬ dowego i teobrominy miesza sie w róznych ilosciach z jednometylomocznikiem i wyra¬ bia z tego pastylki.Przyklad IV. Z mieszaniny, zawieraja¬ cej 2 czesci wagowe dwuetylobarbituranu sodowego, 1 czesc wagowa mocznika i 1 czesc wagowa cukru mlecznego wyrabia sie pastylki od 0,5 do 1,0 g. PL PLIt has been observed that urea and its water-soluble derivatives may be used in the preparation of lozenges and similar medicinal products. Urea is not poisonous and its taste is not unpleasant. Moreover, it has the advantage that it is not hygroscopic, so that there is no need to use water-binding admixtures. water-soluble substances, such as sugar, milk sugar, sodium bicarbonate, etc. Example L 2 parts by weight of urea are mixed exactly with 1 part by weight of sublimate, then lozenges are conventionally expressed from this mixture. , 5 g. Example IL Silver nitrate and urea in equal amounts are thoroughly mixed and extruded from this mixture by stamens. Example III. A mixture of sodium salicylate and theobromine is mixed in varying amounts with the monomethylurea and made into pellets. Example IV. From a mixture containing 2 parts by weight of sodium diethylbarbiturate, 1 part by weight of urea and 1 part by weight of milk sugar, lozenges of 0.5 to 1.0 g are made. EN EN
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL9461B1 true PL9461B1 (en) | 1928-11-30 |
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