PT100155A - Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do carcinoma das celulas nao pequenas do pulmao e composicoes farmaceuticas - Google Patents
Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do carcinoma das celulas nao pequenas do pulmao e composicoes farmaceuticasInfo
- Publication number
- PT100155A PT100155A PT100155A PT10015592A PT100155A PT 100155 A PT100155 A PT 100155A PT 100155 A PT100155 A PT 100155A PT 10015592 A PT10015592 A PT 10015592A PT 100155 A PT100155 A PT 100155A
- Authority
- PT
- Portugal
- Prior art keywords
- camptotecin
- medication
- pharmaceutical compositions
- non small
- analog compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 201000009030 Carcinoma Diseases 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000002685 pulmonary effect Effects 0.000 title 1
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical class C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 abstract 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65893791A | 1991-02-21 | 1991-02-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT100155A true PT100155A (pt) | 1993-05-31 |
| PT100155B PT100155B (pt) | 1999-09-30 |
Family
ID=24643331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT100155A PT100155B (pt) | 1991-02-21 | 1992-02-21 | Uso de compostos analogos da camptotecina na obtencao de um medicamento para uso no tratamento do carcinoma das celulas nao pequenas do pulmao e composicoes farmaceuticas |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5756512A (pt) |
| EP (1) | EP0572549B1 (pt) |
| JP (1) | JP2738979B2 (pt) |
| KR (1) | KR930702984A (pt) |
| AT (1) | ATE227991T1 (pt) |
| AU (2) | AU1531992A (pt) |
| CA (1) | CA2103707C (pt) |
| DE (1) | DE69232852T2 (pt) |
| DK (1) | DK0572549T3 (pt) |
| ES (1) | ES2187500T3 (pt) |
| MX (1) | MX9200755A (pt) |
| PT (1) | PT100155B (pt) |
| WO (1) | WO1992014471A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997019085A1 (en) * | 1995-11-22 | 1997-05-29 | Research Triangle Institute | Camptothecin compounds with combined topoisomerase i inhibition and dna alkylation properties |
| US6096336A (en) * | 1996-01-30 | 2000-08-01 | The Stehlin Foundation For Cancer Research | Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs |
| US6352996B1 (en) | 1999-08-03 | 2002-03-05 | The Stehlin Foundation For Cancer Research | Liposomal prodrugs comprising derivatives of camptothecin and methods of treating cancer using these prodrugs |
| US6228855B1 (en) | 1999-08-03 | 2001-05-08 | The Stehlin Foundation For Cancer Research | Aromatic esters of camptothecins and methods to treat cancers |
| US6858596B2 (en) | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
| JP6783224B2 (ja) | 2014-04-04 | 2020-11-11 | デル マー ファーマシューティカルズ | 肺の非小細胞癌腫及び卵巣癌を処置するためのジアンヒドロガラクチトール及びその類縁体又は誘導体の使用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5004758A (en) * | 1987-12-01 | 1991-04-02 | Smithkline Beecham Corporation | Water soluble camptothecin analogs useful for inhibiting the growth of animal tumor cells |
-
1992
- 1992-02-07 DK DK92907467T patent/DK0572549T3/da active
- 1992-02-07 KR KR1019930702491A patent/KR930702984A/ko not_active Ceased
- 1992-02-07 JP JP4507270A patent/JP2738979B2/ja not_active Expired - Fee Related
- 1992-02-07 ES ES92907467T patent/ES2187500T3/es not_active Expired - Lifetime
- 1992-02-07 DE DE69232852T patent/DE69232852T2/de not_active Expired - Fee Related
- 1992-02-07 AT AT92907467T patent/ATE227991T1/de not_active IP Right Cessation
- 1992-02-07 EP EP92907467A patent/EP0572549B1/en not_active Expired - Lifetime
- 1992-02-07 WO PCT/US1992/001034 patent/WO1992014471A1/en not_active Ceased
- 1992-02-07 AU AU15319/92A patent/AU1531992A/en not_active Abandoned
- 1992-02-07 CA CA002103707A patent/CA2103707C/en not_active Expired - Fee Related
- 1992-02-21 MX MX9200755A patent/MX9200755A/es unknown
- 1992-02-21 PT PT100155A patent/PT100155B/pt not_active IP Right Cessation
-
1995
- 1995-12-14 AU AU40427/95A patent/AU699436B2/en not_active Ceased
-
1996
- 1996-07-16 US US08/699,046 patent/US5756512A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE227991T1 (de) | 2002-12-15 |
| JP2738979B2 (ja) | 1998-04-08 |
| EP0572549A1 (en) | 1993-12-08 |
| DE69232852D1 (de) | 2003-01-02 |
| EP0572549B1 (en) | 2002-11-20 |
| KR930702984A (ko) | 1993-11-29 |
| AU4042795A (en) | 1996-02-22 |
| CA2103707A1 (en) | 1992-08-22 |
| WO1992014471A1 (en) | 1992-09-03 |
| EP0572549A4 (pt) | 1994-01-12 |
| DK0572549T3 (da) | 2003-01-06 |
| AU699436B2 (en) | 1998-12-03 |
| US5756512A (en) | 1998-05-26 |
| ES2187500T3 (es) | 2003-06-16 |
| CA2103707C (en) | 2003-12-09 |
| MX9200755A (es) | 1992-08-01 |
| PT100155B (pt) | 1999-09-30 |
| AU1531992A (en) | 1992-09-15 |
| DE69232852T2 (de) | 2003-09-04 |
| HK1012267A1 (en) | 1999-07-30 |
| JPH06505741A (ja) | 1994-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2080837T5 (es) | Uso de acido hialuronico en combinacion con acido ascorbico, agentes antitumorales y/o faine para el tratamiento del cancer. | |
| ES2162615T3 (es) | Metodo para tratar o prevenir diabetes de tipo 1 mediante la administracion oral de insulina. | |
| ATE231863T1 (de) | 6-amino-purinderivate mit pde-iv inhibierender wirkung | |
| ES2150496T3 (es) | Cicloalquilimidazopiridinas condensadas. | |
| SE8504945D0 (sv) | Pharmaceutical compositions containing anthracycline glycosides | |
| SE8504967L (sv) | Farmaceutisk komposition och forfarande for behandling av kroppen | |
| ES2156839T1 (es) | Medicamento que contiene alginato e implante para tratar la fibrosis. | |
| ATE177640T1 (de) | Pharmazeutische zusammensetzung zur wund-, narben- und keloidbehandlung | |
| BR0109672A (pt) | Uso de zd6126 ou de um seu sal farmaceuticamente aceitável e um de: um agente antitumoral de plantina e um taxano, composição farmacêutica, produto de combinação, kit, e, método para a produção de um efeito de danificação vascular em um animal de sangue quente | |
| HU213677B (en) | Pharmaceutical compositions for preventing and treating tumor diseases, and process for producing them | |
| EP0230264A3 (en) | Pharmaceutical composition for nasal application, process for its preparation and its use | |
| DE2962580D1 (en) | 7-phenyl-quinolizidine derivatives (i), their preparation, pharmaceutical compositions containing them and (i) for use in treating diseases | |
| NO810480L (no) | Anologifremgangsmaate for fremstilling av terapeutisk aktive 1,3,4-oksadiazolylfenol-derivater | |
| DK0572549T3 (da) | Behandling af ikke-småcellet lungecarcinom | |
| DE3373978D1 (en) | Composition for the care or treatment of the human skin | |
| ES8603270A1 (es) | Procedimiento para preparar liposomas que contiene alergenoso fracciones de alergenos inhalables | |
| KR880004810A (ko) | 소화성 궤양 치료제 | |
| ES2031462T3 (es) | Procedimiento para producir 1-b-d-arabinofuranosilcitosina-5'-estearilfosfato monosodico y monohidrato de la misma, y compuesto farmaceutico que contiene esta ultima. | |
| EG17992A (en) | Preparation of a medicament for arthritis and theumatism | |
| ZA837972B (en) | Method of analgesic treatment and pharmaceutical compositions | |
| PT98538A (pt) | Processo de preparacao de factor de crescimento humano epidermico (hegf) dos seus congeneres e de composicoes farmaceuticas que os contem | |
| BR0015329A (pt) | Uso de óxido nìtrico para o tratamento de constrição das vias aéreas | |
| EG14024A (en) | Pharmaceutical compositions and their use in the profyloxis and or treatment of certain diseases | |
| ES2087178T3 (es) | Disulfato de ws7622a, procedimiento para su preparacion y su uso. | |
| GB2019720A (en) | S-adenosyl-L-homocysteine and salts thereof for use in therapy |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19930122 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990622 |
|
| MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20091222 |