PT100671A - Sal de l-ascorbato de 16-descarboxi-16-hidroxi-metilanfotericina b e processo para a sua preparacao - Google Patents

Sal de l-ascorbato de 16-descarboxi-16-hidroxi-metilanfotericina b e processo para a sua preparacao

Info

Publication number
PT100671A
PT100671A PT10067192A PT10067192A PT100671A PT 100671 A PT100671 A PT 100671A PT 10067192 A PT10067192 A PT 10067192A PT 10067192 A PT10067192 A PT 10067192A PT 100671 A PT100671 A PT 100671A
Authority
PT
Portugal
Prior art keywords
methananothyericin
discarboxy
hydroxy
preparation
ascorbate salt
Prior art date
Application number
PT10067192A
Other languages
English (en)
Other versions
PT100671B (pt
Inventor
Alexander Richard Greenlees
David Timothy Macpherson
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of PT100671A publication Critical patent/PT100671A/pt
Publication of PT100671B publication Critical patent/PT100671B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT10067192A 1991-07-11 1992-07-09 Sal de l-ascorbato de 16-descarboxi-16-hidroxi-metilanfotericina b e processo para a sua preparacao PT100671B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919114949A GB9114949D0 (en) 1991-07-11 1991-07-11 Novel compounds

Publications (2)

Publication Number Publication Date
PT100671A true PT100671A (pt) 1993-10-29
PT100671B PT100671B (pt) 1999-07-30

Family

ID=10698172

Family Applications (1)

Application Number Title Priority Date Filing Date
PT10067192A PT100671B (pt) 1991-07-11 1992-07-09 Sal de l-ascorbato de 16-descarboxi-16-hidroxi-metilanfotericina b e processo para a sua preparacao

Country Status (7)

Country Link
AU (1) AU2230892A (pt)
GB (1) GB9114949D0 (pt)
IE (1) IE922264A1 (pt)
MX (1) MX9204031A (pt)
PT (1) PT100671B (pt)
TW (1) TW199894B (pt)
WO (1) WO1993001203A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192713B1 (en) 1999-05-18 2007-03-20 President And Fellows Of Harvard College Stabilized compounds having secondary structure motifs
US7981998B2 (en) 2006-12-14 2011-07-19 Aileron Therapeutics, Inc. Bis-sulfhydryl macrocyclization systems
BRPI0720306A2 (pt) 2006-12-14 2014-02-04 Aileron Therapeutics Inc Sistemas de macrociclização da bis-sufidrila
PL2118123T3 (pl) 2007-01-31 2016-06-30 Dana Farber Cancer Inst Inc Stabilizowane peptydy p53 i ich zastosowania
CA2678941C (en) 2007-02-23 2018-11-27 Aileron Therapeutics, Inc. Triazole macrocycle systems
JP5631201B2 (ja) 2007-03-28 2014-11-26 プレジデント アンド フェローズ オブ ハーバード カレッジ ステッチングされたポリペプチド
AU2010204648B2 (en) 2009-01-14 2016-09-01 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
JP2013505300A (ja) 2009-09-22 2013-02-14 エルロン・セラピューティクス・インコーポレイテッド ペプチド模倣大環状分子
KR102104762B1 (ko) 2010-08-13 2020-04-24 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
EP2768518A4 (en) 2011-10-18 2015-05-27 Aileron Therapeutics Inc PEPTIDOMIMETIC MACROCYCLES
CA2864120A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
RU2642299C2 (ru) 2012-02-15 2018-01-24 Эйлерон Терапьютикс, Инк. P53 пептидомиметические макроциклы
BR112015009470A2 (pt) 2012-11-01 2019-12-17 Aileron Therapeutics Inc aminoácidos dissubstituídos e seus métodos de preparação e uso
CN107106642B (zh) 2014-09-24 2021-02-26 艾瑞朗医疗公司 拟肽大环化合物及其制剂
EP3197478A4 (en) 2014-09-24 2018-05-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
JP2018516844A (ja) 2015-03-20 2018-06-28 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその使用
US10059741B2 (en) 2015-07-01 2018-08-28 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
EP3347372A4 (en) 2015-09-10 2019-09-04 Aileron Therapeutics, Inc. PEPTIDOMIMETIC MACROCYCLES AS MODULATORS OF MCL-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8829592D0 (en) * 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
GB8829593D0 (en) * 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
EP0431874A1 (en) * 1989-12-08 1991-06-12 Beecham Group p.l.c. Novel compounds
EP0431870A1 (en) * 1989-12-08 1991-06-12 Beecham Group p.l.c. Amphotericin B derivatives

Also Published As

Publication number Publication date
IE922264A1 (en) 1993-01-13
PT100671B (pt) 1999-07-30
MX9204031A (es) 1993-01-01
WO1993001203A1 (en) 1993-01-21
TW199894B (pt) 1993-02-11
GB9114949D0 (en) 1991-08-28
AU2230892A (en) 1993-02-11

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19930607

FG3A Patent granted, date of granting

Effective date: 19990415

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20001031