PT100883A - Processo para a preparacao de derivados de taxano utilizando alcoxidos metalicos e b-lactamas - Google Patents

Processo para a preparacao de derivados de taxano utilizando alcoxidos metalicos e b-lactamas

Info

Publication number: PT100883A
Authority: PT; Portugal
Prior art keywords: furyl; thienyl; new; substd; taxanes
Prior art date: 1991-09-23

Application number

PT100883A

Other languages

English (en)

Other versions

PT100883B (pt

Inventor

Robert A Holton

Original Assignee

Univ Florida State

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-23

Filing date

1992-09-21

Publication date

1994-02-28

1992-09-21 Application filed by Univ Florida State filed Critical Univ Florida State

1994-02-28 Publication of PT100883A publication Critical patent/PT100883A/pt

1999-07-30 Publication of PT100883B publication Critical patent/PT100883B/pt

Links

229940123237 Taxane Drugs 0.000 title 1
230000000259 anti-tumor effect Effects 0.000 title 1
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 3
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
-1 ethylene, propylene Chemical group 0.000 abstract 3
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 2
125000002030 1,2-phenylene group Chemical group [H]C1=C([H])C([*:1])=C([*:2])C([H])=C1[H] 0.000 abstract 1
GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 abstract 1
MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 abstract 1
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
125000000636 p-nitrophenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)[N+]([O-])=O 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

PT100883A 1991-09-23 1992-09-21 Processo para a preparacao de derivados de taxano utilizando alcoxidos metalicos e b-lactamas PT100883B (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US76380591A	1991-09-23	1991-09-23
US86384992A	1992-04-06	1992-04-06

Publications (2)

Publication Number	Publication Date
PT100883A true PT100883A (pt)	1994-02-28
PT100883B PT100883B (pt)	1999-07-30

Family

ID=51348512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT100883A PT100883B (pt)	1991-09-23	1992-09-21	Processo para a preparacao de derivados de taxano utilizando alcoxidos metalicos e b-lactamas

Country Status (7)

Country	Link
CN (1)	CN1048982C (pt)
IL (1)	IL103191A (pt)
MX (1)	MX9205369A (pt)
MY (1)	MY109876A (pt)
NZ (1)	NZ244459A (pt)
PT (1)	PT100883B (pt)
TW (1)	TW229204B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1393438B (zh) *	2001-06-21	2010-11-03	中国医学科学院药物研究所	紫杉烷衍生物及其制法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4942184A (en) *	1988-03-07	1990-07-17	The United States Of America As Represented By The Department Of Health And Human Services	Water soluble, antineoplastic derivatives of taxol

1992
- 1992-09-16 IL IL10319192A patent/IL103191A/en not_active IP Right Cessation
- 1992-09-21 MY MYPI92001682A patent/MY109876A/en unknown
- 1992-09-21 PT PT100883A patent/PT100883B/pt active IP Right Grant
- 1992-09-22 MX MX9205369A patent/MX9205369A/es unknown
- 1992-09-23 CN CN92112286A patent/CN1048982C/zh not_active Expired - Fee Related
- 1992-09-23 NZ NZ244459A patent/NZ244459A/xx not_active IP Right Cessation
- 1992-10-21 TW TW081108377A patent/TW229204B/zh active

Also Published As

Publication number	Publication date
TW229204B (pt)	1994-09-01
IL103191A (en)	2001-07-24
CN1048982C (zh)	2000-02-02
NZ244459A (en)	1995-01-27
PT100883B (pt)	1999-07-30
MY109876A (en)	1997-09-30
MX9205369A (es)	1993-03-01
CN1075315A (zh)	1993-08-18
IL103191A0 (en)	1993-02-21

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Legal Events

Date	Code	Title	Description
1994-02-28	BB1A	Laying open of patent application	Effective date: 19930630
1999-07-30	FG3A	Patent granted, date of granting	Effective date: 19990414