PT101105A - Medicamento contendo dicloridrato de melarsomina e processo de sintese deste composto - Google Patents

Medicamento contendo dicloridrato de melarsomina e processo de sintese deste composto

Info

Publication number: PT101105A
Authority: PT; Portugal
Prior art keywords: dichloridrate; melarsomine; compound; synthesis process; medication containing
Prior art date: 1991-12-02

Application number

PT101105A

Other languages

English (en)

Other versions

PT101105B (pt

Inventor

Gerard Wolff

Jean Pierre Etchegaray

Floc H Robert

Frtrick Lubert

Regine Jackie Anne-Mari Mazars

Original Assignee

Rhone Merieux

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-12-02

Filing date

1992-11-30

Publication date

1994-03-31

1992-11-30 Application filed by Rhone Merieux filed Critical Rhone Merieux

1994-03-31 Publication of PT101105A publication Critical patent/PT101105A/pt

1999-10-29 Publication of PT101105B publication Critical patent/PT101105B/pt

Links

230000015572 biosynthetic process Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
MGEOLZFMLHYCFZ-UHFFFAOYSA-N melarsomine Chemical compound C1=CC([As](SCCN)SCCN)=CC=C1NC1=NC(N)=NC(N)=N1 MGEOLZFMLHYCFZ-UHFFFAOYSA-N 0.000 title 1
229960002234 melarsomine Drugs 0.000 title 1
238000000034 method Methods 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/80—Heterocyclic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/74—Aromatic compounds

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

PT101105A 1991-12-02 1992-11-30 Medicamento contendo dicloridrato de melarsomina e processo de sintese deste composto PT101105B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR919114904A FR2684382B1 (fr)	1991-12-02	1991-12-02	Medicaments et preparations pures de dichlorhydrate de melarsomine, leur procede d'obtention et produits intermediaires obtenus.

Publications (2)

Publication Number	Publication Date
PT101105A true PT101105A (pt)	1994-03-31
PT101105B PT101105B (pt)	1999-10-29

Family

ID=9419573

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT101105A PT101105B (pt)	1991-12-02	1992-11-30	Medicamento contendo dicloridrato de melarsomina e processo de sintese deste composto

Country Status (15)

Country	Link
US (3)	US5459263A (pt)
JP (1)	JP3578277B2 (pt)
AU (1)	AU667329B2 (pt)
BR (1)	BR9204643A (pt)
CA (1)	CA2083766C (pt)
ES (1)	ES2039311B1 (pt)
FR (1)	FR2684382B1 (pt)
GR (1)	GR920100526A (pt)
IT (1)	IT1256117B (pt)
MA (1)	MA22723A1 (pt)
MX (1)	MX9206890A (pt)
MY (1)	MY111175A (pt)
PH (1)	PH31115A (pt)
PT (1)	PT101105B (pt)
TW (1)	TW358099B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2684382B1 (fr) *	1991-12-02	1994-10-21	Rhone Merieux	Medicaments et preparations pures de dichlorhydrate de melarsomine, leur procede d'obtention et produits intermediaires obtenus.
US6191123B1 (en) *	1999-03-19	2001-02-20	Parker Hughes Institute	Organic-arsenic compounds
AUPQ296799A0 (en)	1999-09-20	1999-10-14	Unisearch Limited	A cell-membrane impermeable trivalent organoarsenical derivative and use thereof
EP1563099B1 (en)	2002-11-07	2009-07-22	Newsouth Innovations Pty Limited	Induction of the mitochondrial permeability transition
US6686344B1 (en)	2003-01-30	2004-02-03	Paker Hughes Institute	Organic-arsonic compounds
USD546574S1 (en)	2005-06-01	2007-07-17	Steelcase Development Corporation	Seating unit
EP2069371B1 (en)	2006-11-01	2013-03-13	NewSouth Innovations Pty Limited	Organo-arsenoxide compounds and use thereof
US8373412B2 (en) *	2009-01-23	2013-02-12	Baker Hughes Incorporated	NMR-LWD imaging tool
US8324895B2 (en) *	2009-01-23	2012-12-04	Baker Hughes Incorporated	MWD/LWD NMR imaging with long echo trains
CN102558234B (zh) *	2011-04-08	2015-01-07	浙江工商大学	一种通过对氨基苯胂酸重氮化制备阿散酸制剂的方法
CN102558235B (zh) *	2011-04-08	2015-01-07	浙江工商大学	一种通过三甲氧苄氨嘧啶重氮化制备阿散酸制剂的方法
US20140051840A1 (en) *	2012-08-17	2014-02-20	The Curators Of The University Of Missouri	Arsenic complexes for potential diagnostic applications
US9593052B2 (en)	2012-08-17	2017-03-14	The Curators Of The University Of Missouri	Arsenic complexes for potential diagnostic applications

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE437342A (pt) *	1938-12-23	1900-01-01
CH242529A (de) *	1940-12-10	1946-05-15	Friedheim Ernst Albert Hermann	Verfahren zur Darstellung von m-(2,4-Diamino-1,3,5-triazinyl-(6))-amino-phenylarsinoxyd.
NL60802C (pt) *	1940-12-10
US2422724A (en) *	1944-01-20	1947-06-24	Ernst A H Friedheim	Substituted 1,3,5-triazinyl-(6)-aminophenyl-arsenic compounds
US2400547A (en) *	1944-01-20	1946-05-21	Ernst A H Friedheim	Substituted 1, 3, 5-triazinyl-(6)-aminophenyl-arsenic compounds
US2390091A (en) *	1944-06-03	1945-11-27	Ernst A H Friedheim	Substituted 1,3,5-triazinyl-(6)-aminophenyl-arsenic compounds
CH254164A (de) *	1946-11-16	1948-04-15	Dr Friedheim Ernst A H	Verfahren zur Darstellung von p-(2,4-Diamino-1,3,5-triazinyl-(6)-aminophenyl-arsenoxyd.
CH245837A (de) *	1946-11-16	1946-11-30	Dr Friedheim Ernst A H	Verfahren zur Darstellung von p-2,4-Diamino-1,3,5-triazinyl-(6)-amino-phenyl-arsenoxyd.
US2659723A (en) *	1947-01-28	1953-11-17	Ernst A H Friedheim	Triazine organometallic compounds and process for preparing same
US2593434A (en) *	1947-02-19	1952-04-22	Ernst A H Friedheim	Propylene glycol solution of arsenic medicaments
US3482171A (en) *	1966-07-15	1969-12-02	Itt	Bidirectional electronic phase shifter
BE786573A (fr) *	1971-07-20	1973-01-22	Hoechst Ag	Medicament a base de composes arsenicaux organiques et de derives du benzimidazole
US3856971A (en) *	1971-07-20	1974-12-24	E Friedheim	Method of combating filariasis in dogs
GB2024008B (en) *	1978-06-28	1983-02-16	Merck & Co Inc	Compositions for treating trypanosomiasis infections
ZW8781A1 (en) *	1980-05-23	1981-12-16	Hoffmann La Roche	2-nitroimidazoles and preparation thereof
US4514390A (en) *	1982-04-12	1985-04-30	The Rockefeller University	Melaminylthioarsenites
FR2572730B1 (fr) *	1984-11-02	1987-12-11	Centre Nat Rech Scient	Nouveaux derives de l'arsenic, leur preparation et leur application, notamment comme medicaments antiparasitaires
FR2640269B1 (fr) *	1988-12-13	1991-03-15	Maes Ludo	Composes organometalliques, leurs modes de preparation et compositions pharmaceutiques les contenant
FR2684382B1 (fr) *	1991-12-02	1994-10-21	Rhone Merieux	Medicaments et preparations pures de dichlorhydrate de melarsomine, leur procede d'obtention et produits intermediaires obtenus.

1991
- 1991-12-02 FR FR919114904A patent/FR2684382B1/fr not_active Expired - Lifetime
1992
- 1992-11-25 PH PH45320A patent/PH31115A/en unknown
- 1992-11-25 ES ES09202376A patent/ES2039311B1/es not_active Expired - Fee Related
- 1992-11-25 CA CA002083766A patent/CA2083766C/en not_active Expired - Lifetime
- 1992-11-25 IT ITMI922692A patent/IT1256117B/it active IP Right Grant
- 1992-11-26 GR GR920100526A patent/GR920100526A/el unknown
- 1992-11-27 AU AU29720/92A patent/AU667329B2/en not_active Expired
- 1992-11-27 MY MYPI92002180A patent/MY111175A/en unknown
- 1992-11-30 PT PT101105A patent/PT101105B/pt not_active IP Right Cessation
- 1992-11-30 MX MX9206890A patent/MX9206890A/es unknown
- 1992-12-01 BR BR9204643A patent/BR9204643A/pt not_active Application Discontinuation
- 1992-12-01 MA MA23013A patent/MA22723A1/fr unknown
- 1992-12-02 JP JP34986692A patent/JP3578277B2/ja not_active Expired - Lifetime
- 1992-12-02 US US07/984,934 patent/US5459263A/en not_active Expired - Lifetime
- 1992-12-11 TW TW081109949A patent/TW358099B/zh not_active IP Right Cessation
1995
- 1995-06-02 US US08/459,797 patent/US5635499A/en not_active Expired - Lifetime
1996
- 1996-09-05 US US08/707,613 patent/US5770733A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
BR9204643A (pt)	1993-06-08
TW358099B (en)	1999-05-11
IT1256117B (it)	1995-11-28
ES2039311B1 (es)	1997-08-16
CA2083766A1 (en)	1993-06-03
ITMI922692A1 (it)	1994-05-25
ES2039311A1 (es)	1993-09-16
AU667329B2 (en)	1996-03-21
CA2083766C (en)	2002-09-10
MA22723A1 (fr)	1993-07-01
ITMI922692A0 (it)	1992-11-25
FR2684382A1 (fr)	1993-06-04
PH31115A (en)	1998-02-23
AU2972092A (en)	1993-06-03
US5459263A (en)	1995-10-17
JPH0624960A (ja)	1994-02-01
FR2684382B1 (fr)	1994-10-21
GR920100526A (el)	1993-08-31
PT101105B (pt)	1999-10-29
MY111175A (en)	1999-09-30
JP3578277B2 (ja)	2004-10-20
US5770733A (en)	1998-06-23
US5635499A (en)	1997-06-03
MX9206890A (es)	1993-08-01

Legal Events

Date

Code

Title

Description

1994-03-31

BB1A

Laying open of patent application

Effective date: 19930818

1999-10-29

FG3A

Patent granted, date of granting

Effective date: 19990701

2014-07-08

MM4A

Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20140701

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