PT1012319E - Vectores de expressao de insectos - Google Patents

Vectores de expressao de insectos

Info

Publication number: PT1012319E
Authority: PT; Portugal
Prior art keywords: vectors; disclosed; insect; provides; heterologous proteins
Prior art date: 1997-03-27

Application number

PT98913479T

Other languages

English (en)

Inventor

Thomas A Grigliatti

Dave A Theilmann

Thomas A Pfeifer

Dwayne D Hegedus

Original Assignee

Univ British Columbia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-27

Filing date

1998-03-26

Publication date

2005-06-30

1998-01-28 Priority claimed from CA002221819A external-priority patent/CA2221819A1/en

1998-03-26 Application filed by Univ British Columbia filed Critical Univ British Columbia

2005-06-30 Publication of PT1012319E publication Critical patent/PT1012319E/pt

Links

241000238631 Hexapoda Species 0.000 title abstract 5
239000013604 expression vector Substances 0.000 title 1
102000004169 proteins and genes Human genes 0.000 abstract 3
108090000623 proteins and genes Proteins 0.000 abstract 3
239000013598 vector Substances 0.000 abstract 2
QRBLKGHRWFGINE-UGWAGOLRSA-N 2-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2r,3s,4s,5s,6s)-3-[(2s,3r,4r,5s)-4-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)- Chemical compound N=1C(C=2SC=C(N=2)C(N)=O)CSC=1CCNC(=O)C(C(C)=O)NC(=O)C(C)C(O)C(C)NC(=O)C(C(O[C@H]1[C@@]([C@@H](O)[C@H](O)[C@H](CO)O1)(C)O[C@H]1[C@@H]([C@](O)([C@@H](O)C(CO)O1)C(N)=O)O)C=1NC=NC=1)NC(=O)C1=NC(C(CC(N)=O)NCC(N)C(N)=O)=NC(N)=C1C QRBLKGHRWFGINE-UGWAGOLRSA-N 0.000 abstract 1
108010006654 Bleomycin Proteins 0.000 abstract 1
LTQCLFMNABRKSH-UHFFFAOYSA-N Phleomycin Natural products N=1C(C=2SC=C(N=2)C(N)=O)CSC=1CCNC(=O)C(C(O)C)NC(=O)C(C)C(O)C(C)NC(=O)C(C(OC1C(C(O)C(O)C(CO)O1)OC1C(C(OC(N)=O)C(O)C(CO)O1)O)C=1NC=NC=1)NC(=O)C1=NC(C(CC(N)=O)NCC(N)C(N)=O)=NC(N)=C1C LTQCLFMNABRKSH-UHFFFAOYSA-N 0.000 abstract 1
108010035235 Phleomycins Proteins 0.000 abstract 1
108010084455 Zeocin Proteins 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
229940088710 antibiotic agent Drugs 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
229960001561 bleomycin Drugs 0.000 abstract 1
OYVAGSVQBOHSSS-UAPAGMARSA-O bleomycin A2 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-UAPAGMARSA-O 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
CWCMIVBLVUHDHK-ZSNHEYEWSA-N phleomycin D1 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC[C@@H](N=1)C=1SC=C(N=1)C(=O)NCCCCNC(N)=N)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C CWCMIVBLVUHDHK-ZSNHEYEWSA-N 0.000 abstract 1
239000013605 shuttle vector Substances 0.000 abstract 1
230000001131 transforming effect Effects 0.000 abstract 1
230000017105 transposition Effects 0.000 abstract 1
241000701447 unidentified baculovirus Species 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6432—Coagulation factor Xa (3.4.21.6)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/69—Increasing the copy number of the vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21006—Coagulation factor Xa (3.4.21.6)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/005—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB
- C12N2830/006—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination repressible enhancer/promoter combination, e.g. KRAB tet repressible
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/55—Vector systems having a special element relevant for transcription from bacteria
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Endocrinology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

PT98913479T 1997-03-27 1998-03-26 Vectores de expressao de insectos PT1012319E (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4994697P	1997-03-27	1997-03-27
CA002221819A CA2221819A1 (en)	1997-03-27	1998-01-28	Insect expression vectors

Publications (1)

Publication Number	Publication Date
PT1012319E true PT1012319E (pt)	2005-06-30

Family

ID=25679855

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98913479T PT1012319E (pt)	1997-03-27	1998-03-26	Vectores de expressao de insectos

Country Status (9)

Country	Link
EP (1)	EP1012319B1 (pt)
JP (1)	JP3688718B2 (pt)
AT (1)	ATE290091T1 (pt)
AU (1)	AU736334B2 (pt)
DE (1)	DE69829189T2 (pt)
DK (1)	DK1012319T3 (pt)
ES (1)	ES2239387T3 (pt)
PT (1)	PT1012319E (pt)
WO (1)	WO1998044141A2 (pt)

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US6264301B1 (en) *	1998-05-11	2001-07-24	Hewlett-Packard Company	Method and apparatus for identifying parameters in a replaceable printing component
US7276459B1 (en)	2000-05-04	2007-10-02	Kimberly-Clark Worldwide, Inc.	Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6423804B1 (en)	1998-12-31	2002-07-23	Kimberly-Clark Worldwide, Inc.	Ion-sensitive hard water dispersible polymers and applications therefor
US6713414B1 (en)	2000-05-04	2004-03-30	Kimberly-Clark Worldwide, Inc.	Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US8236561B2 (en)	1999-04-15	2012-08-07	Crucell Holland B.V.	Efficient production of IgA in recombinant mammalian cells
US7604960B2 (en)	1999-04-15	2009-10-20	Crucell Holland B.V.	Transient protein expression methods
US6855544B1 (en)	1999-04-15	2005-02-15	Crucell Holland B.V.	Recombinant protein production in a human cell
US7297680B2 (en)	1999-04-15	2007-11-20	Crucell Holland B.V.	Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
GB9924721D0 (en)	1999-10-19	1999-12-22	Craig Roger	Protein production system
ES2241665T5 (es) *	1999-10-19	2008-09-01	Minos Biosystems Limited	Sistema de produccion de proteinas.
US7527961B2 (en)	1999-11-26	2009-05-05	Crucell Holland B.V.	Production of vaccines
US7192759B1 (en)	1999-11-26	2007-03-20	Crucell Holland B.V.	Production of vaccines
US7521220B2 (en)	1999-11-26	2009-04-21	Crucell Holland B.V.	Production of vaccines
US6444214B1 (en)	2000-05-04	2002-09-03	Kimberly-Clark Worldwide, Inc.	Ion-sensitive, water-dispersible polymers, a method of making same and items using same
US6835678B2 (en)	2000-05-04	2004-12-28	Kimberly-Clark Worldwide, Inc.	Ion sensitive, water-dispersible fabrics, a method of making same and items using same
DE10056059A1 (de)	2000-11-11	2002-07-25	Univ Eberhard Karls	Differenzierung auslösende Substanzen
AU2002224199A1 (en) *	2001-10-29	2003-06-23	Crucell Holland B.V.	Methods and means for producing proteins with predetermined post-translational modifications
EA008220B1 (ru) *	2001-10-29	2007-04-27	Круселл Холланд Б.В.	Композиция, включающая эритропоэтинподобные молекулы, и способы ее применения
ATE384785T1 (de)	2001-12-07	2008-02-15	Crucell Holland Bv	Herstellung von viren, virusisolaten, und impfstoffen
NZ542585A (en)	2003-05-09	2007-11-30	Crucell Holland Bv	Cultures of PER.C6-immortalized cells and processes for culturing the same to increase product yields therefrom
SG170802A1 (en)	2006-03-31	2011-05-30	Solexa Inc	Systems and devices for sequence by synthesis analysis
RU2626590C2 (ru) *	2015-12-18	2017-07-28	федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ)	Генетическая конструкция для экспрессии генов в клетках насекомого polypedilum vanderplanki
US20190390221A1 (en) *	2016-11-02	2019-12-26	David Kiewlich	Plasmid vectors for expression of large nucleic acid transgenes
RU2766887C1 (ru) *	2021-03-29	2022-03-16	федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ)	Генетическая конструкция c геном белка-ингибитора апоптоза, предназначенная для экспрессии чужеродных генов в клетках насекомого Polypedilum vanderplanki в условиях повышенного радиационного фона
CN114480496B (zh) *	2022-02-23	2024-05-07	新乡医学院	一种昆虫细胞用双荧光素酶报告基因载体、构建方法、重组载体及应用

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EP0127839B1 (en) *	1983-05-27	1992-07-15	THE TEXAS A&M UNIVERSITY SYSTEM	Method for producing a recombinant baculovirus expression vector
AU5351494A (en) *	1993-10-07	1995-05-01	G.D. Searle & Co.	Method of producing recombinant eukaryotic viruses in bacteria
US5627048A (en) *	1994-11-04	1997-05-06	Research Corporation Technologies, Inc.	Aedes aegypti densovirus expression system

1998
- 1998-03-26 AT AT98913479T patent/ATE290091T1/de not_active IP Right Cessation
- 1998-03-26 AU AU68174/98A patent/AU736334B2/en not_active Ceased
- 1998-03-26 ES ES98913479T patent/ES2239387T3/es not_active Expired - Lifetime
- 1998-03-26 DE DE69829189T patent/DE69829189T2/de not_active Expired - Fee Related
- 1998-03-26 WO PCT/CA1998/000282 patent/WO1998044141A2/en not_active Ceased
- 1998-03-26 DK DK98913479T patent/DK1012319T3/da active
- 1998-03-26 EP EP98913479A patent/EP1012319B1/en not_active Expired - Lifetime
- 1998-03-26 JP JP54101098A patent/JP3688718B2/ja not_active Expired - Fee Related
- 1998-03-26 PT PT98913479T patent/PT1012319E/pt unknown

Also Published As

Publication number	Publication date
DE69829189T2 (de)	2006-02-16
WO1998044141A2 (en)	1998-10-08
WO1998044141A3 (en)	1999-01-07
AU736334B2 (en)	2001-07-26
EP1012319A2 (en)	2000-06-28
EP1012319B1 (en)	2005-03-02
ES2239387T3 (es)	2005-09-16
AU6817498A (en)	1998-10-22
JP2001516225A (ja)	2001-09-25
JP3688718B2 (ja)	2005-08-31
DK1012319T3 (da)	2005-06-13
DE69829189D1 (de)	2005-04-07
ATE290091T1 (de)	2005-03-15

Publication	Publication Date	Title
DK1012319T3 (da)	2005-06-13	Insektekspressionsvektorer
IL143596A0 (en)	2002-04-21	Vascular endothelial cell growth factor antagonists and uses thereof
WO1998049286A3 (en)	1999-03-25	Directed evolution of enzymes and antibodies
AU4639396A (en)	1996-06-26	Cytokine designated lerk-7
AR018023A1 (es)	2001-10-31	Procedimiento para la fabricacion de polipeptidos con glicosilacion apropiada
IL137178A0 (en)	2001-07-24	Il-18 receptors
AU5579099A (en)	2000-03-14	Electrochemical affinity assay
PT694042E (pt)	2005-02-28	Inibidor do factor de crescimento de celulas endoteliais vasculares
EP1325932A3 (en)	2003-10-29	Anti-vegf antibodies
ATE313640T1 (de)	2006-01-15	Adenovirales fiberprotein mit einem kurzen schaft und seine verwendung
BR9206578A (pt)	1995-04-11	Seqüência de DNA sintético tendo melhorada atividade inseticida em milho.
AU6954398A (en)	1998-11-11	Antagonistic anti-avb3 integrin antibodies
ATE255420T1 (de)	2003-12-15	Verwendung von tumorzellen zeitversetzt in kombination mit intakten antikörpern zur immunisierung
DE69934241D1 (de)	2007-01-11	Agonistische antikörper gegen tie2
AU2098997A (en)	1997-09-10	Modified nuclear glucocorticoid receptor, fusion protein, and dna fragments coding for said receptor and said fusion protein
BR0317160A (pt)	2005-11-01	Diversidade de transmissão de antena comutada
DK1190079T3 (da)	2006-10-09	Regulering af genekspression i eukaryote celler
ES2196298T3 (es)	2003-12-16	Antena omnidireccional.
WO2001023412A3 (en)	2001-08-23	Methods of screening for agents which inhibit aggregation of polypeptides
DK1051502T3 (da)	2007-02-26	Meget effektiv styret ekspression af eksogene gener i E. coli
MX9802730A (es)	1998-09-30	Agonistas receptores hematopoyeticos multifuncionales.
WO1998017810A3 (en)	1998-10-15	Multi-functional chimeric hematopoietic receptor agonists
DE69933679D1 (de)	2006-11-30	Darstellung des profils und katalogisierung von exprimierten proteinmarkern
WO2000050570A3 (en)	2000-12-14	Compositions and methods for modulating growth or differentiation of growth-factor dependent cells
DK0745122T3 (da)	2009-03-30	Galninreceptor, nukleinsyrer, transformerede celler og anvendelser heraf