PT101446A - Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes. - Google Patents

Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes.

Info

Publication number: PT101446A
Authority: PT; Portugal
Prior art keywords: chloramphenicol; solutions; solubility; stability; increasing
Prior art date: 1994-01-24

Application number

PT10144694A

Other languages

English (en)

Other versions

PT101446B (pt

Inventor

Manuel Torres Marques

Ana Maria Jorge Baptista

Helena Maria Cabral Marques

Isabel Joglar Chitas

Manuel Rodrigues De Carvalho

Original Assignee

Oftalder Especialidades Dermo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-24

Filing date

1994-01-24

Publication date

1995-08-09

1994-01-24 Application filed by Oftalder Especialidades Dermo filed Critical Oftalder Especialidades Dermo

1994-01-24 Priority to PT10144694A priority Critical patent/PT101446B/pt

1995-08-09 Publication of PT101446A publication Critical patent/PT101446A/pt

1996-11-29 Publication of PT101446B publication Critical patent/PT101446B/pt

Links

WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 title abstract 6
229960005091 chloramphenicol Drugs 0.000 title abstract 6
229920000858 Cyclodextrin Polymers 0.000 title abstract 5
238000000034 method Methods 0.000 title abstract 4
230000015572 biosynthetic process Effects 0.000 title 1
229940097362 cyclodextrins Drugs 0.000 title 1
HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 4
WPRAXAOJIODQJR-UHFFFAOYSA-N 1-(3,4-dimethylphenyl)ethanone Chemical compound CC(=O)C1=CC=C(C)C(C)=C1 WPRAXAOJIODQJR-UHFFFAOYSA-N 0.000 abstract 1
239000002671 adjuvant Substances 0.000 abstract 1
229910021538 borax Inorganic materials 0.000 abstract 1
KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
239000004327 boric acid Substances 0.000 abstract 1
235000010339 sodium tetraborate Nutrition 0.000 abstract 1
BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Landscapes

Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

PT10144694A 1994-01-24 1994-01-24 Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes. PT101446B (pt)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
PT10144694A PT101446B (pt)	1994-01-24	1994-01-24	Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes.

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PT10144694A PT101446B (pt)	1994-01-24	1994-01-24	Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes.

Publications (2)

Publication Number	Publication Date
PT101446A true PT101446A (pt)	1995-08-09
PT101446B PT101446B (pt)	1996-11-29

Family

ID=20085362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT10144694A PT101446B (pt)	1994-01-24	1994-01-24	Metodo para aumentar a solubilidade e estabilidade do cloranfenicol, atraves da formacao de complexos de inclusao com ciclodextrinas, solucoes contendo o referido complexo de inclusao e processo para a preparacao dessas solucoes.

Country Status (1)

Country	Link
PT (1)	PT101446B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101549159B (zh) *	2009-05-25	2012-02-29	昆明振华制药厂有限公司	羟丙基-β-环糊精在氯霉素滴眼剂中的应用及方法

1994
- 1994-01-24 PT PT10144694A patent/PT101446B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT101446B (pt)	1996-11-29

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Legal Events

Date	Code	Title	Description
1995-08-09	BB1A	Laying open of patent application	Effective date: 19950307
1996-11-29	FG3A	Patent granted, date of granting	Effective date: 19960820
2005-09-30	PC3A	Transfer or assignment	Owner name: LABORATORIO EDOL - PRODUTOS FARMACEUTICOS, S.A, PT Effective date: 20050802
2010-08-03	MM4A	Annulment/lapse due to non-payment of fees;searched & examined patent	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20100726