PT102294A - Processo para a preparacao de esteres de acido 7-beta-¬(z)-(2)-aminotiazol-4-il)-2-(metoxicarbonilmetoxiimino)acetamido|-3-vinil-3-cefeme-4-carboxilico para utilizacao na preparacao de cefixima - Google Patents

Processo para a preparacao de esteres de acido 7-beta-¬(z)-(2)-aminotiazol-4-il)-2-(metoxicarbonilmetoxiimino)acetamido|-3-vinil-3-cefeme-4-carboxilico para utilizacao na preparacao de cefixima Download PDF

Info

Publication number: PT102294A
Authority: PT; Portugal
Prior art keywords: formula; compound; preparation; aliphatic halogenated; image
Prior art date: 1999-01-29

Application number

PT102294A

Other languages

English (en)

Other versions

PT102294B (pt

Inventor

Anil Kumar Sharma

Baldev Raj

Kumar Sethi Dr Madhuresh

Debashis Das

Original Assignee

J K Drugs & Pharmaceuticals Lt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-29

Filing date

1999-04-26

Publication date

2000-02-29

1999-04-26 Application filed by J K Drugs & Pharmaceuticals Lt filed Critical J K Drugs & Pharmaceuticals Lt

2000-02-29 Publication of PT102294A publication Critical patent/PT102294A/pt

2001-05-31 Publication of PT102294B publication Critical patent/PT102294B/pt

Links

238000002360 preparation method Methods 0.000 title abstract 5
OKBVVJOGVLARMR-QSWIMTSFSA-N cefixime Chemical compound S1C(N)=NC(C(=N\OCC(O)=O)\C(=O)N[C@@H]2C(N3C(=C(C=C)CS[C@@H]32)C(O)=O)=O)=C1 OKBVVJOGVLARMR-QSWIMTSFSA-N 0.000 title abstract 2
229960002129 cefixime Drugs 0.000 title abstract 2
150000002148 esters Chemical class 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 6
-1 aliphatic halogenated hydrocarbons Chemical class 0.000 abstract 5
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
QQVDYSUDFZZPSU-UHFFFAOYSA-M chloromethylidene(dimethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)=CCl QQVDYSUDFZZPSU-UHFFFAOYSA-M 0.000 abstract 2
XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 2
UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 1
238000013019 agitation Methods 0.000 abstract 1
238000001035 drying Methods 0.000 abstract 1
238000000605 extraction Methods 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000007530 organic bases Chemical class 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
239000012047 saturated solution Substances 0.000 abstract 1
238000005406 washing Methods 0.000 abstract 1

Classifications

- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Cephalosporin Compounds (AREA)

PT102294A 1999-01-29 1999-04-26 Processo para a preparacao de esteres de acido 7-beta-¬(z)-(2)-aminotiazol-4-il)-2-(metoxicarbonilmetoxiimino)acetamido|-3-vinil-3-cefeme-4-carboxilico para utilizacao na preparacao de cefixima PT102294B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IN76BO1999 IN185090B (pt)	1999-01-29	1999-01-29

Publications (2)

Publication Number	Publication Date
PT102294A true PT102294A (pt)	2000-02-29
PT102294B PT102294B (pt)	2001-05-31

Family

ID=11077362

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT102294A PT102294B (pt)	1999-01-29	1999-04-26	Processo para a preparacao de esteres de acido 7-beta-¬(z)-(2)-aminotiazol-4-il)-2-(metoxicarbonilmetoxiimino)acetamido\|-3-vinil-3-cefeme-4-carboxilico para utilizacao na preparacao de cefixima

Country Status (2)

Country	Link
IN (1)	IN185090B (pt)
PT (1)	PT102294B (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN117430526A (zh) *	2023-12-20	2024-01-23	山东金城柯瑞化学有限公司	头孢克肟侧链开环酸杂质及其制备方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN115710282A (zh) *	2022-11-23	2023-02-24	湖北凌晟药业股份有限公司	一种头孢克肟甲酯杂质及其制备方法

1999
- 1999-01-29 IN IN76BO1999 patent/IN185090B/en unknown
- 1999-04-26 PT PT102294A patent/PT102294B/pt not_active IP Right Cessation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN117430526A (zh) *	2023-12-20	2024-01-23	山东金城柯瑞化学有限公司	头孢克肟侧链开环酸杂质及其制备方法
CN117430526B (zh) *	2023-12-20	2024-04-02	山东金城柯瑞化学有限公司	头孢克肟侧链开环酸杂质及其制备方法

Also Published As

Publication number	Publication date
PT102294B (pt)	2001-05-31
IN185090B (pt)	2000-11-11

Similar Documents

Publication	Publication Date	Title
NL930130I1 (nl)	1993-11-01	Nieuwe cefalosporine-derivaten werkwijze ter bereiding daarvan en als antibiotica bruikbare geneesmiddelen deze derivaten bevatten
US4476308B1 (pt)	1987-03-10
GB1046506A (en)	1966-10-26	Guanidine compounds and process for their manufacture
KR860007265A (ko)	1986-10-10	β-락탐 항생물질의 제조방법
BRPI0409471B8 (pt)	2021-05-25	processo para preparação de 2-cianopirrolidinas n-substituídas
DE3363545D1 (en)	1986-06-19	Substituted 1,4-dihydropyridines, method for their preparation and their use as pharmaceuticals
ZA832044B (en)	1983-12-28	Imidazolyphenyl-tetrahydropyridazines,processes for their preparation and pharmaceutical preparation containing them
JPS5645464A (en)	1981-04-25	Substituted oxiranecarboxylic acid* drug containing it* its manufacture and alphaamethylenecarboxylic acid and drug containing alphaamethylenecarboxylic acid
DK159441C (da)	1991-03-18	11-substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-on-derivater, laegemidler indeholdende disse forbindelser og analogifremgangsmaade til forbindelsernes fremstilling
PT102294A (pt)	2000-02-29	Processo para a preparacao de esteres de acido 7-beta-¬(z)-(2)-aminotiazol-4-il)-2-(metoxicarbonilmetoxiimino)acetamido\|-3-vinil-3-cefeme-4-carboxilico para utilizacao na preparacao de cefixima
ES8107192A1 (es)	1981-10-01	Un procedimiento para la preparacion de un compuesto sele- ccionado entre el grupo formado por una imidazolilurea
CA2379974A1 (en)	2001-02-01	Preparation of compounds useful for the detection of hypoxia
JPS5724389A (en)	1982-02-08	Novel cephem compound, its preparation, and preventive and remedy for bacteriosis
IL86723A (en)	1993-01-14	Guanidine-related compounds comprising a tetraphenyl- borate ion and process for their preparation
GB1009477A (en)	1965-11-10	Novel process for preparing heterocyclic compounds
DE60325631D1 (de)	2009-02-12	Verfahren zur herstellung von 2,6-dihalo-para-trifluoromethylanilin
ATE101391T1 (de)	1994-02-15	Verfahren zur herstellung von in stellung 3 durch eine halogenierte gesaettigte kette substituierten cyclopropancarbonsaeurederivaten.
DK161069C (da)	1991-11-18	Fremgangsmaade til fremstilling af eventuelt halogenerede anilinderivater ved ammonolyse af halogenerede benzenforbindelser
KR840005107A (ko)	1984-11-03	피리미디온 및 그의 산부가염의 제조방법
CA2296902A1 (en)	2000-08-19	Process for the preparation of organic azides
DK0426557T3 (da)	1995-03-27	Fremgangsmåde til fremstilling af (1R,2R)-2-(3-pyridyl)tetrahydrothiopyran-2-carbothioamid-1-oxider, mellemprodukter anvendt ved denne fremgangsmåde og fremstilling af disse mellemprodukter
SE7603640L (sv)	1976-09-28	Sett for framstellning av olosliga, biologiskt aktiva foreningar
JPS5282791A (en)	1977-07-11	Preparation of 7-amino compounds
ES2043784T3 (es)	1994-01-01	Procedimiento de preparacion de compuestos guanidinicos.
EP0128437A3 (en)	1985-10-30	Nortropine derivative, process for its preparation and its use

Legal Events

Date

Code

Title

Description

2000-02-29

BB1A

Laying open of patent application

Effective date: 19990630

2001-05-31

FG3A

Patent granted, date of granting

Effective date: 20010223

2003-01-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20021031